{"id":26784,"date":"2025-10-06T09:53:26","date_gmt":"2025-10-06T09:53:26","guid":{"rendered":"https:\/\/www.dlongwood.com\/?post_type=productos&#038;p=26784"},"modified":"2026-03-18T12:58:55","modified_gmt":"2026-03-18T12:58:55","slug":"devyser-cftr-for-ngs","status":"publish","type":"productos","link":"https:\/\/www.dlongwood.com\/en\/product-catalog\/devyser-cftr-for-ngs\/","title":{"rendered":"Devyser CFTR for NGS"},"content":{"rendered":"\n<!-- Bloque de Estilos Scoped (Aislados, Blindados y Escalados a 14px) -->\n<style>\n    \/* Importaci\u00f3n de fuentes corporativas *\/\n    @import url('https:\/\/fonts.googleapis.com\/css2?family=Playfair+Display:wght@400;700&family=Raleway:wght@300;400;500;600;700&display=swap');\n\n    \/* Contenedor Principal Aislado *\/\n    .dlw-prod-wrapper {\n        font-family: 'Raleway', sans-serif !important;\n        color: #000000 !important;\n        line-height: 1.6 !important;\n        background-color: transparent !important;\n        padding: 0 !important;\n        max-width: 100% !important;\n        text-align: left !important;\n        display: block !important;\n        font-size: 14px !important; \/* ANCLAJE: Ignora el tama\u00f1o root defectuoso de Bricks *\/\n    }\n\n    \/* Variables CSS locales *\/\n    .dlw-prod-wrapper {\n        --dlw-blue-dark: #003a70;\n        --dlw-blue-cyan: #00a1e0;\n        --dlw-light-bg: #f9fbfd;\n        --dlw-grey-bg: #f4f6f8;\n        --dlw-border: #e1e8f0;\n    }\n\n    \/* Titulares H2 *\/\n    .dlw-prod-wrapper h2 {\n        font-family: 'Playfair Display', serif !important;\n        color: var(--dlw-blue-dark) !important;\n        margin-top: 2em !important;\n        margin-bottom: 0.8em !important;\n        font-size: 1.8em !important;\n        font-weight: 700 !important;\n        border-bottom: 2px solid var(--dlw-border) !important;\n        padding-bottom: 10px !important;\n        display: block !important;\n    }\n\n    \/* P\u00e1rrafos est\u00e1ndar *\/\n    .dlw-prod-wrapper p {\n        font-weight: 400 !important;\n        margin-bottom: 1.2em !important;\n        text-align: justify !important;\n        font-size: 1.25em !important; \/* 1.25em sobre 14px = 17.5px reales *\/\n        color: #333333 !important;\n    }\n\n    \/* Negritas corporativas *\/\n    .dlw-prod-wrapper strong {\n        color: var(--dlw-blue-dark) !important;\n        font-weight: 700 !important;\n    }\n\n    \/* Lead \/ Descripci\u00f3n Corta (Caja Azul Corporativa) *\/\n    .dlw-lead-box {\n        background-color: var(--dlw-blue-dark) !important;\n        color: #ffffff !important;\n        padding: 2.5em 3em !important;\n        margin-bottom: 2.5em !important;\n        border-radius: 8px !important;\n        box-shadow: 0 6px 25px rgba(0, 58, 112, 0.2) !important;\n    }\n\n    .dlw-lead-box p {\n        color: #ffffff !important;\n        font-size: 1.35em !important;\n        font-weight: 500 !important;\n        margin-bottom: 0 !important;\n        text-align: left !important;\n    }\n\n    .dlw-lead-box strong {\n        color: var(--dlw-blue-cyan) !important;\n    }\n\n    \/* Im\u00e1genes insertadas *\/\n    .dlw-prod-img {\n        width: 100% !important;\n        height: auto !important;\n        display: block !important;\n        margin: 2.5em auto !important;\n        max-width: 90% !important;\n        border-radius: 6px !important;\n        box-shadow: none !important;\n        transition: transform 0.4s cubic-bezier(0.165, 0.84, 0.44, 1) !important;\n    }\n\n    .dlw-prod-img:hover {\n        transform: scale(1.04) !important;\n        cursor: zoom-in !important;\n    }\n\n    \/* Listas est\u00e1ndar (Puntos) *\/\n    .dlw-list {\n        display: flex !important;\n        flex-direction: column !important;\n        margin-bottom: 2em !important;\n        padding-left: 0 !important;\n    }\n\n    .dlw-list-item {\n        position: relative !important;\n        padding-left: 1.5em !important;\n        margin-bottom: 0.8em !important;\n        text-align: left !important;\n        font-size: 1.25em !important;\n        color: #333333 !important;\n        display: block !important;\n    }\n\n    .dlw-list-item::before {\n        content: \"\u2022\" !important;\n        position: absolute !important;\n        left: 0 !important;\n        color: var(--dlw-blue-cyan) !important;\n        font-weight: bold !important;\n    }\n\n    \/* Sub-listas anidadas para limpieza visual *\/\n    .dlw-sub-list {\n        margin-top: 0.5em !important;\n        margin-bottom: 0.5em !important;\n        padding-left: 1.5em !important;\n    }\n\n    .dlw-sub-list-item {\n        position: relative !important;\n        padding-left: 1.2em !important;\n        margin-bottom: 0.4em !important;\n        font-size: 0.95em !important;\n        color: #555555 !important;\n        display: block !important;\n    }\n\n    .dlw-sub-list-item::before {\n        content: \"-\" !important;\n        position: absolute !important;\n        left: 0 !important;\n        color: var(--dlw-grey) !important;\n        font-weight: bold !important;\n    }\n\n    \/* Listas Check (Aspectos Clave) *\/\n    .dlw-check-list {\n        display: grid !important;\n        grid-template-columns: 1fr 1fr !important;\n        gap: 1.5em 2em !important;\n        margin: 2em 0 !important;\n        background-color: var(--dlw-light-bg) !important;\n        padding: 2.5em !important;\n        border-radius: 8px !important;\n        border-left: 6px solid var(--dlw-blue-cyan) !important;\n    }\n\n    .dlw-check-item {\n        display: flex !important;\n        align-items: flex-start !important;\n        gap: 12px !important;\n        font-size: 1.2em !important;\n        color: var(--dlw-blue-dark) !important;\n        font-weight: 500 !important;\n        line-height: 1.4 !important;\n    }\n\n    .dlw-check-icon {\n        width: 24px !important;\n        height: 24px !important;\n        min-width: 24px !important;\n        fill: var(--dlw-blue-cyan) !important;\n        margin-top: 2px !important;\n    }\n\n    \/* Tablas Corporativas (Referencias) *\/\n    .dlw-table {\n        width: 100% !important;\n        border-collapse: collapse !important;\n        margin-bottom: 2.5em !important;\n        background-color: #ffffff !important;\n        box-shadow: 0 2px 10px rgba(0,0,0,0.03) !important;\n        border-radius: 6px !important;\n        overflow: hidden !important;\n    }\n\n    .dlw-table th {\n        background-color: var(--dlw-blue-dark) !important;\n        color: #ffffff !important;\n        text-align: left !important;\n        padding: 15px 20px !important;\n        font-family: 'Raleway', sans-serif !important;\n        font-weight: 600 !important;\n        text-transform: uppercase !important;\n        font-size: 1.1em !important;\n        letter-spacing: 0.5px !important;\n    }\n\n    .dlw-table td {\n        padding: 15px 20px !important;\n        border-bottom: 1px solid var(--dlw-border) !important;\n        vertical-align: middle !important;\n        font-size: 1.2em !important;\n        color: #333333 !important;\n    }\n    \n    .dlw-table tr:hover td {\n        background-color: var(--dlw-light-bg) !important;\n    }\n\n    .dlw-table tr:last-child td {\n        border-bottom: 2px solid var(--dlw-blue-cyan) !important;\n    }\n\n    .dlw-ref-code {\n        font-family: 'Courier New', Courier, monospace !important;\n        font-weight: 700 !important;\n        color: var(--dlw-blue-dark) !important;\n    }\n\n    \/* Acordeones (Tablas Desplegables) *\/\n    .dlw-accordion {\n        background-color: #ffffff !important;\n        border: 1px solid var(--dlw-border) !important;\n        border-radius: 6px !important;\n        margin-bottom: 1.5em !important;\n        overflow: hidden !important;\n        transition: all 0.3s ease !important;\n    }\n\n    .dlw-accordion-header {\n        background-color: var(--dlw-blue-dark) !important;\n        color: #ffffff !important;\n        padding: 15px 20px !important;\n        font-family: 'Raleway', sans-serif !important;\n        font-weight: 600 !important;\n        text-transform: uppercase !important;\n        font-size: 1.1em !important;\n        letter-spacing: 0.5px !important;\n        cursor: pointer !important;\n        list-style: none !important;\n        position: relative !important;\n        display: flex !important;\n        justify-content: space-between !important;\n        align-items: center !important;\n        transition: background-color 0.3s ease !important;\n    }\n\n    \/* Ocultar la flecha por defecto de details\/summary *\/\n    .dlw-accordion-header::-webkit-details-marker {\n        display: none !important;\n    }\n\n    \/* Icono + \/ x personalizado *\/\n    .dlw-accordion-header::after {\n        content: '+' !important;\n        font-size: 1.8em !important;\n        line-height: 1 !important;\n        color: var(--dlw-blue-cyan) !important;\n        transition: transform 0.3s ease !important;\n    }\n\n    .dlw-accordion[open] .dlw-accordion-header::after {\n        transform: rotate(45deg) !important; \/* Gira el + para que parezca una x *\/\n    }\n\n    .dlw-accordion[open] .dlw-accordion-header {\n        border-bottom: 2px solid var(--dlw-blue-cyan) !important;\n    }\n\n    \/* Ajuste de la tabla dentro del acorde\u00f3n *\/\n    .dlw-accordion-content .dlw-table {\n        margin-bottom: 0 !important;\n        box-shadow: none !important;\n        border-radius: 0 !important;\n        border-top: none !important;\n    }\n\n    \/* Responsive *\/\n    @media (max-width: 768px) {\n        .dlw-lead-box { padding: 1.8em !important; }\n        .dlw-check-list { grid-template-columns: 1fr !important; padding: 1.5em !important; }\n        .dlw-prod-img { max-width: 100% !important; }\n        \n        \/* Tablas Responsive *\/\n        .dlw-table, .dlw-table thead, .dlw-table tbody, .dlw-table th, .dlw-table td, .dlw-table tr { display: block !important; }\n        .dlw-table thead tr { position: absolute !important; top: -9999px !important; left: -9999px !important; }\n        .dlw-table tr { border-bottom: 2px solid var(--dlw-blue-cyan) !important; margin-bottom: 15px !important; }\n        .dlw-table td { border: none !important; position: relative !important; padding-left: 45% !important; }\n        .dlw-table td::before { position: absolute !important; top: 15px !important; left: 15px !important; width: 40% !important; white-space: nowrap !important; font-weight: bold !important; color: var(--dlw-blue-dark) !important; font-size: 0.9em !important; text-transform: uppercase !important; }\n        .dlw-table td:nth-of-type(1)::before { content: \"Reference\" !important; }\n        .dlw-table td:nth-of-type(2)::before { content: \"Description\" !important; }\n    }\n<\/style>\n\n<!-- ==========================================\n     CONTENIDO UNIFICADO Y BLINDADO\n     ========================================== -->\n<div class=\"dlw-prod-wrapper\">\n\n    <!-- Operating Principle (Lead Box) -->\n    <div class=\"dlw-lead-box\">\n        <p><strong>Operating Principle:<\/strong> The Devyser CFTR NGS kit redefines the genetic diagnosis of cystic fibrosis by offering a comprehensive and precise solution, validated for clinical use. With a unique single-tube library preparation approach, this kit optimizes the CFTR gene analysis process, significantly reducing hands-on time and contamination risk while improving diagnostic accuracy.<\/p>\n    <\/div>\n\n    <!-- Clinical applications -->\n    <h2>Clinical Applications<\/h2>\n    <p>Advances in NGS techniques allow laboratories to perform a comprehensive diagnosis by analyzing the entire CFTR gene, covering known and novel variants. The integrated analysis software, along with databases such as CFTR2, ensures that variants are classified with high reliability.<\/p>\n\n    <!-- Benefits -->\n    <h2>Benefits<\/h2>\n    <div class=\"dlw-list\">\n        <span class=\"dlw-list-item\"><strong>High efficiency and optimal performance:<\/strong> A single tube per sample minimizes the risk of pre-analytical errors and contamination.<\/span>\n        <span class=\"dlw-list-item\"><strong>Ease of use:<\/strong> &lt;45 minutes of hands-on time and a total turnaround time of less than 5 hours, accelerating diagnostic turnaround times.<\/span>\n        <span class=\"dlw-list-item\"><strong>Broad coverage including:<\/strong>\n            <div class=\"dlw-sub-list\">\n                <span class=\"dlw-sub-list-item\">All exonic regions of the gene + a minimum of 20 bp at the 5&#8242; end and 10 bp at the 3&#8242; end of the exon\/intron junctions.<\/span>\n                <span class=\"dlw-sub-list-item\">Promoter region.<\/span>\n                <span class=\"dlw-sub-list-item\">Clinically relevant deep intronic variants.<\/span>\n            <\/div>\n        <\/span>\n        <span class=\"dlw-list-item\"><strong>Complete solution:<\/strong> Allows the analysis of SNVs and indels, as well as CNVs and identification of specific variants such as poly-T and TG repeats.<\/span>\n        <span class=\"dlw-list-item\"><strong>Adaptability:<\/strong> Integration with validated analysis software increases flexibility for laboratories with different needs.<\/span>\n        <span class=\"dlw-list-item\"><strong>Compatible<\/strong> with DNA samples extracted from peripheral blood and dried blood spots.<\/span>\n    <\/div>\n\n    <!-- Image -->\n    <img decoding=\"async\" src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2025\/10\/Dvysr_Imagen-1-768x432.webp\" alt=\"Devyser CFTR for NGS\" class=\"dlw-prod-img\" title=\"\">\n\n    <!-- Technology used -->\n    <h2>Technology Used<\/h2>\n    <p>Multiplex PCR technology with targeted enrichment and subsequent library preparation for NGS workflows. The indices added to the samples come pre-dispensed in strip or plate format, minimizing the risk of contamination. Furthermore, the process includes a post-pooling library cleanup for all samples. The entire workflow is CE-IVD validated and supported by validated software solutions, including CNV analysis, enabling you to obtain precise and reliable results.<\/p>\n\n    <!-- Intended audience\/user -->\n    <h2>Intended Audience\/User<\/h2>\n    <p>Ideal for genetics and molecular biology laboratories requiring comprehensive and reliable analysis of the CFTR gene, especially in newborn screening programs, prenatal testing, and genetic counseling.<\/p>\n\n    <!-- Key Features -->\n    <h2>Key Features<\/h2>\n    <div class=\"dlw-check-list\">\n        <div class=\"dlw-check-item\">\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n            <span>Comprehensive coverage of the CFTR gene, including deep intronic variants and the promoter region.<\/span>\n        <\/div>\n        <div class=\"dlw-check-item\">\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n            <span>Direct detection of CNVs and identification of poly-T variants and TG repeats.<\/span>\n        <\/div>\n        <div class=\"dlw-check-item\">\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n            <span>Standardized and validated CE-IVD workflow.<\/span>\n        <\/div>\n        <div class=\"dlw-check-item\">\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n            <span>Less than 45 minutes of hands-on time.<\/span>\n        <\/div>\n        <div class=\"dlw-check-item\">\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n            <span>Minimal risk of sample mix-ups or contamination.<\/span>\n        <\/div>\n        <div class=\"dlw-check-item\">\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n            <span>Compatible with validated bioinformatics analysis software.<\/span>\n        <\/div>\n    <\/div>\n\n    <!-- Presentation Details (Accordions) -->\n    <h2>Ordering Information<\/h2>\n\n    <details class=\"dlw-accordion\">\n        <summary class=\"dlw-accordion-header\">CE-IVD Devyser CFTR Kits<\/summary>\n        <div class=\"dlw-accordion-content\">\n            <table class=\"dlw-table\">\n                <tbody>\n                    <tr>\n                        <td width=\"30%\" class=\"dlw-ref-code\">8-A101-8<\/td>\n                        <td width=\"70%\">8 tests<\/td>\n                    <\/tr>\n                    <tr>\n                        <td class=\"dlw-ref-code\">8-A101-24<\/td>\n                        <td>24 tests<\/td>\n                    <\/tr>\n                    <tr>\n                        <td class=\"dlw-ref-code\">8-A101-96<\/td>\n                        <td>96 tests<\/td>\n                    <\/tr>\n                <\/tbody>\n            <\/table>\n        <\/div>\n    <\/details>\n\n    <details class=\"dlw-accordion\">\n        <summary class=\"dlw-accordion-header\">RUO Devyser CFTR Kits<\/summary>\n        <div class=\"dlw-accordion-content\">\n            <table class=\"dlw-table\">\n                <tbody>\n                    <tr>\n                        <td width=\"30%\" class=\"dlw-ref-code\">8-A103-8<\/td>\n                        <td width=\"70%\">8 tests<\/td>\n                    <\/tr>\n                    <tr>\n                        <td class=\"dlw-ref-code\">8-A103-24<\/td>\n                        <td>24 tests<\/td>\n                    <\/tr>\n                    <tr>\n                        <td class=\"dlw-ref-code\">8-A103-96<\/td>\n                        <td>96 tests<\/td>\n                    <\/tr>\n                <\/tbody>\n            <\/table>\n        <\/div>\n    <\/details>\n\n    <details class=\"dlw-accordion\">\n        <summary class=\"dlw-accordion-header\">Accessories<\/summary>\n        <div class=\"dlw-accordion-content\">\n            <table class=\"dlw-table\">\n                <tbody>\n                    <tr>\n                        <td width=\"30%\" class=\"dlw-ref-code\">8-A200<\/td>\n                        <td width=\"70%\">Devyser Index Plate A<\/td>\n                    <\/tr>\n                    <tr>\n                        <td class=\"dlw-ref-code\">8-A204<\/td>\n                        <td>Devyser Library Clean<\/td>\n                    <\/tr>\n                <\/tbody>\n            <\/table>\n        <\/div>\n    <\/details>\n\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Operating Principle: The Devyser CFTR NGS kit redefines the genetic diagnosis of cystic fibrosis by offering a comprehensive and precise solution, validated for clinical use. With a unique single-tube library preparation approach, this kit optimizes the CFTR gene analysis process, significantly reducing hands-on time and contamination risk while improving diagnostic accuracy. Clinical Applications Advances in [&hellip;]<\/p>\n","protected":false},"featured_media":26790,"template":"","tecnologias":[36],"marcas":[514],"familias":[283,293,441],"class_list":["post-26784","productos","type-productos","status-publish","has-post-thumbnail","hentry","tecnologias-next-generation-sequencing-ngs","marcas-dvysr_en","familias-molecular-genetics","familias-cystic-fibrosis","familias-targeted_study_of_specific_pathologies"],"_links":{"self":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/26784","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos"}],"about":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/types\/productos"}],"version-history":[{"count":1,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/26784\/revisions"}],"predecessor-version":[{"id":26787,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/26784\/revisions\/26787"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media\/26790"}],"wp:attachment":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media?parent=26784"}],"wp:term":[{"taxonomy":"tecnologias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/tecnologias?post=26784"},{"taxonomy":"marcas","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/marcas?post=26784"},{"taxonomy":"familias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/familias?post=26784"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}