{"id":27025,"date":"2025-10-07T13:38:26","date_gmt":"2025-10-07T13:38:26","guid":{"rendered":"https:\/\/www.dlongwood.com\/?post_type=productos&#038;p=27025"},"modified":"2026-04-09T10:27:04","modified_gmt":"2026-04-09T10:27:04","slug":"trusight-hereditary-cancer-panel","status":"publish","type":"productos","link":"https:\/\/www.dlongwood.com\/en\/product-catalog\/trusight-hereditary-cancer-panel\/","title":{"rendered":"TruSight&#x2122; Hereditary Cancer Panel"},"content":{"rendered":"\n<!-- Bloque de Estilos Scoped (Aislados, Blindados y Escalados a 14px) -->\n<style>\n    \/* Importaci\u00f3n de fuentes corporativas *\/\n    @import url('https:\/\/fonts.googleapis.com\/css2?family=Playfair+Display:wght@400;700&family=Raleway:wght@300;400;500;600;700&display=swap');\n\n    \/* Contenedor Principal Aislado *\/\n    .dlw-prod-wrapper {\n        font-family: 'Raleway', sans-serif !important;\n        color: #000000 !important;\n        line-height: 1.6 !important;\n        background-color: transparent !important;\n        padding: 0 !important;\n        max-width: 100% !important;\n        text-align: left !important;\n        display: block !important;\n        font-size: 14px !important; 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}\n        .dlw-check-list { grid-template-columns: 1fr !important; padding: 1.5em !important; }\n        .dlw-prod-img { max-width: 100% !important; }\n    }\n<\/style>\n\n<!-- ==========================================\n     CONTENIDO UNIFICADO Y BLINDADO\n     ========================================== -->\n<div class=\"dlw-prod-wrapper\">\n\n    <!-- Descripci\u00f3n Corta (Lead Box) -->\n    <div class=\"dlw-lead-box\">\n        <p>NGS panel for hereditary cancer studies integrating the analysis of <strong>113 clinically relevant genes<\/strong> with a rapid workflow and high coverage uniformity for the consistent detection of SNVs, indels, and CNVs.<\/p>\n    <\/div>\n\n    <!-- Descripci\u00f3n Detallada -->\n    <h2>Detailed Description<\/h2>\n\n    <h3>Operating Principle<\/h3>\n    <p>An <em>end-to-end<\/em> solution based on hybrid capture of 113 genes (all exons covered plus \u00b120 bp regions) and library preparation via bead-linked transposome (eBLT) tagmentation, delivering ready-to-sequence libraries in 6.5 hours. Compatible with Illumina benchtop sequencing systems. Data processing is performed via BaseSpace&#x2122; or DRAGEN&#x2122;, and features compatibility for tertiary analysis in Emedgene.<\/p>\n\n    <!-- Imagen 1: Workflow -->\n    <img decoding=\"async\" src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/03\/workfloweng.webp\" alt=\"Library preparation workflow\" class=\"dlw-prod-img\" title=\"\">\n\n    <h3>Clinical Applications<\/h3>\n    <p>Designed to support genetic counseling units, oncology, and oncogenetics laboratories in enhancing the diagnosis and risk stratification of patients with hereditary cancer predisposition syndromes through a comprehensive assessment of germline variants associated with these pathologies.<\/p>\n\n    <!-- Imagen 2: Genes incluidos -->\n    <img decoding=\"async\" src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/04\/2.webp\" alt=\"Genes included in key clinical guidelines\" class=\"dlw-prod-img\" title=\"\">\n\n    <h3>Benefits<\/h3>\n    <p>This panel stands out as a reference solution for laboratories seeking efficiency without compromising quality: a fast, streamlined workflow takes you from sample to data in ~48 hours, with only ~2 hours of hands-on time, while excellent coverage uniformity supports the accurate detection of SNVs, indels, and CNVs.<\/p>\n    <p>Furthermore, its high flexibility allows easy scaling to meet different laboratory needs, enabling high-throughput clinical routines.<\/p>\n\n    <!-- Imagen 3: Tabla T\u00e9cnica -->\n    <img decoding=\"async\" src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/04\/row-43-table-3-trusight-hereditary-cancer-panel-022624.webp\" alt=\"TruSight Hereditary Cancer Panel Table\" class=\"dlw-prod-img\" title=\"\">\n\n    <!-- P\u00fablico\/usuario previsto -->\n    <h2>Intended Audience \/ User<\/h2>\n    <p>Laboratories and research groups studying genetic predisposition to cancer that require a multi-gene germline panel with high uniformity and scaling flexibility.<\/p>\n\n    <!-- Aspectos Clave -->\n    <h2>Key Features<\/h2>\n    <div class=\"dlw-check-list\">\n        <div class=\"dlw-check-item\">\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n            <span><strong>Expert-designed coverage:<\/strong> 403 kb total footprint covering 113 genes (all exons \u00b120 bp) with 10,341 probes for curated, comprehensive content, ready for clinical performance.<\/span>\n        <\/div>\n        <div class=\"dlw-check-item\">\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n            <span><strong>Risk stratification capabilities:<\/strong> The panel features 125 integrated SNPs (48 for sample tracking and 77 for polygenic risk score in breast cancer).<\/span>\n        <\/div>\n        <div class=\"dlw-check-item\">\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n            <span><strong>Consistent data quality:<\/strong> Comprehensive and uniform coverage across 113 cancer predisposition genes (\u00b120 bp intronic).<\/span>\n        <\/div>\n        <div class=\"dlw-check-item\">\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n            <span><strong>Analytical confidence:<\/strong> Reliable detection of SNVs, indels, and CNVs with high uniformity and concordance in validations against reference standards.<\/span>\n        <\/div>\n        <div class=\"dlw-check-item\">\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n            <span><strong>Flexible scalability:<\/strong> From 2 to 256 samples per run with an average depth of 300x (minimum 100x).<\/span>\n        <\/div>\n        <div class=\"dlw-check-item\">\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n            <span><strong>Full compatibility:<\/strong> Works with automation systems and all Illumina sequencing instruments.<\/span>\n        <\/div>\n        <div class=\"dlw-check-item\">\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n            <span><strong>High sample input versatility:<\/strong> From genomic DNA to direct blood or saliva samples using the Flex Lysis Reagent kit.<\/span>\n        <\/div>\n    <\/div>\n\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>NGS panel for hereditary cancer studies integrating the analysis of 113 clinically relevant genes with a rapid workflow and high coverage uniformity for the consistent detection of SNVs, indels, and CNVs. Detailed Description Operating Principle An end-to-end solution based on hybrid capture of 113 genes (all exons covered plus \u00b120 bp regions) and library preparation [&hellip;]<\/p>\n","protected":false},"featured_media":27026,"template":"","tecnologias":[36],"marcas":[232],"familias":[283,445,441],"class_list":["post-27025","productos","type-productos","status-publish","has-post-thumbnail","hentry","tecnologias-next-generation-sequencing-ngs","marcas-illumina-en","familias-molecular-genetics","familias-hereditary_cancer","familias-targeted_study_of_specific_pathologies"],"_links":{"self":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/27025","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos"}],"about":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/types\/productos"}],"version-history":[{"count":2,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/27025\/revisions"}],"predecessor-version":[{"id":27031,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/27025\/revisions\/27031"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media\/27026"}],"wp:attachment":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media?parent=27025"}],"wp:term":[{"taxonomy":"tecnologias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/tecnologias?post=27025"},{"taxonomy":"marcas","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/marcas?post=27025"},{"taxonomy":"familias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/familias?post=27025"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}