{"id":27222,"date":"2026-04-14T08:21:57","date_gmt":"2026-04-14T08:21:57","guid":{"rendered":"https:\/\/www.dlongwood.com\/?post_type=productos&#038;p=27222"},"modified":"2026-04-14T08:21:57","modified_gmt":"2026-04-14T08:21:57","slug":"devyser-brca-palb2-ngs","status":"publish","type":"productos","link":"https:\/\/www.dlongwood.com\/en\/product-catalog\/devyser-brca-palb2-ngs\/","title":{"rendered":"Devyser BRCA PALB2 NGS"},"content":{"rendered":"\n<!-- Bloque de Estilos Scoped (Aislados, Blindados y Escalados a 14px) -->\n<style>\n    \/* Importaci\u00f3n de fuentes corporativas *\/\n    @import url('https:\/\/fonts.googleapis.com\/css2?family=Playfair+Display:ital,wght@0,400;0,700;1,400&family=Raleway:wght@300;400;500;600;700&display=swap');\n\n    \/* Contenedor Principal Aislado *\/\n    .dlw-prod-wrapper {\n        font-family: 'Raleway', sans-serif !important;\n        color: #000000 !important;\n        line-height: 1.6 !important;\n        background-color: transparent !important;\n        padding: 0 !important;\n        max-width: 100% !important;\n        text-align: left !important;\n        display: block !important;\n        font-size: 14px !important; \/* ANCLAJE: Ignora el tama\u00f1o root defectuoso de Bricks *\/\n    }\n\n    \/* Variables CSS locales *\/\n    .dlw-prod-wrapper {\n        --dlw-blue-dark: #003a70;\n        --dlw-blue-cyan: #00a1e0;\n        --dlw-light-bg: #f9fbfd;\n        --dlw-grey-bg: #f4f6f8;\n        --dlw-border: #e1e8f0;\n    }\n\n    \/* Titulares H2 *\/\n    .dlw-prod-wrapper h2 {\n        font-family: 'Playfair Display', serif !important;\n        color: var(--dlw-blue-dark) !important;\n        margin-top: 2em !important;\n        margin-bottom: 0.8em !important;\n        font-size: 1.8em !important;\n        font-weight: 700 !important;\n        border-bottom: 2px solid var(--dlw-border) !important;\n        padding-bottom: 10px !important;\n        display: block !important;\n    }\n\n    \/* P\u00e1rrafos est\u00e1ndar *\/\n    .dlw-prod-wrapper p {\n        font-weight: 400 !important;\n        margin-bottom: 1.2em !important;\n        text-align: justify !important;\n        font-size: 1.25em !important; \/* 1.25em sobre 14px = 17.5px reales *\/\n        color: #333333 !important;\n    }\n\n    \/* Negritas corporativas *\/\n    .dlw-prod-wrapper strong {\n        color: var(--dlw-blue-dark) !important;\n        font-weight: 700 !important;\n    }\n\n    \/* Lead \/ Descripci\u00f3n Corta (Caja Azul Corporativa) *\/\n    .dlw-lead-box {\n        background-color: var(--dlw-blue-dark) !important;\n        color: #ffffff !important;\n        padding: 2.5em 3em !important;\n        margin-bottom: 2.5em !important;\n        border-radius: 8px !important;\n        box-shadow: 0 6px 25px rgba(0, 58, 112, 0.2) !important;\n    }\n\n    .dlw-lead-box p {\n        color: #ffffff !important;\n        font-size: 1.35em !important;\n        font-weight: 500 !important;\n        margin-bottom: 0 !important;\n        text-align: left !important;\n    }\n\n    \/* Im\u00e1genes insertadas individuales (Centradas) *\/\n    .dlw-prod-img {\n        width: 100% !important;\n        height: auto !important;\n        display: block !important;\n        margin: 2.5em auto !important;\n        max-width: 85% !important;\n        border-radius: 6px !important;\n        box-shadow: 0 4px 15px rgba(0,0,0,0.06) !important;\n        transition: transform 0.4s cubic-bezier(0.165, 0.84, 0.44, 1) !important;\n    }\n\n    .dlw-prod-img:hover {\n        transform: scale(1.03) !important;\n        cursor: zoom-in !important;\n    }\n\n    \/* Listas est\u00e1ndar (Puntos) *\/\n    .dlw-list {\n        display: flex !important;\n        flex-direction: column !important;\n        margin-bottom: 2em !important;\n        padding-left: 0 !important;\n    }\n\n    .dlw-list-item {\n        position: relative !important;\n        padding-left: 1.5em !important;\n        margin-bottom: 0.8em !important;\n        text-align: left !important;\n        font-size: 1.25em !important;\n        color: #333333 !important;\n        display: block !important;\n    }\n\n    .dlw-list-item::before {\n        content: \"\u2022\" !important;\n        position: absolute !important;\n        left: 0 !important;\n        color: var(--dlw-blue-cyan) !important;\n        font-weight: bold !important;\n        font-size: 1.2em !important;\n        top: -2px !important;\n    }\n\n    \/* Listas Check (Aspectos Clave) *\/\n    .dlw-check-list {\n        display: grid !important;\n        grid-template-columns: 1fr 1fr !important;\n        gap: 1.5em 2em !important;\n        margin: 2em 0 !important;\n        background-color: var(--dlw-light-bg) !important;\n        padding: 2.5em !important;\n        border-radius: 8px !important;\n        border-left: 6px solid var(--dlw-blue-cyan) !important;\n    }\n\n    .dlw-check-item {\n        display: flex !important;\n        align-items: flex-start !important;\n        gap: 12px !important;\n        font-size: 1.2em !important;\n        color: #333333 !important;\n        line-height: 1.4 !important;\n    }\n\n    .dlw-check-icon {\n        width: 24px !important;\n        height: 24px !important;\n        min-width: 24px !important;\n        fill: var(--dlw-blue-cyan) !important;\n        margin-top: 2px !important;\n        flex-shrink: 0 !important;\n    }\n\n    .dlw-check-item:last-child:nth-child(odd) {\n        grid-column: 1 \/ -1 !important;\n    }\n\n    \/* Tablas Corporativas (Referencias) *\/\n    .dlw-table {\n        width: 100% !important;\n        border-collapse: collapse !important;\n        margin-bottom: 2.5em !important;\n        background-color: #ffffff !important;\n        box-shadow: 0 2px 10px rgba(0,0,0,0.03) !important;\n        border-radius: 6px !important;\n        overflow: hidden !important;\n    }\n\n    .dlw-table th {\n        background-color: var(--dlw-blue-dark) !important;\n        color: #ffffff !important;\n        text-align: left !important;\n        padding: 15px 20px !important;\n        font-family: 'Raleway', sans-serif !important;\n        font-weight: 600 !important;\n        text-transform: uppercase !important;\n        font-size: 1.1em !important;\n        letter-spacing: 0.5px !important;\n    }\n\n    .dlw-table td {\n        padding: 15px 20px !important;\n        border-bottom: 1px solid var(--dlw-border) !important;\n        vertical-align: middle !important;\n        font-size: 1.2em !important;\n        color: #333333 !important;\n    }\n    \n    .dlw-table tr:hover td {\n        background-color: var(--dlw-light-bg) !important;\n    }\n\n    .dlw-table tr:last-child td {\n        border-bottom: 2px solid var(--dlw-blue-cyan) !important;\n    }\n\n    .dlw-ref-code {\n        font-family: 'Courier New', Courier, monospace !important;\n        font-weight: 700 !important;\n        color: var(--dlw-blue-dark) !important;\n    }\n\n    \/* Acordeones (Tablas Desplegables) *\/\n    .dlw-accordion {\n        background-color: #ffffff !important;\n        border: 1px solid var(--dlw-border) !important;\n        border-radius: 6px !important;\n        margin-bottom: 1.5em !important;\n        overflow: hidden !important;\n        transition: all 0.3s ease !important;\n    }\n\n    .dlw-accordion-header {\n        background-color: var(--dlw-blue-dark) !important;\n        color: #ffffff !important;\n        padding: 15px 20px !important;\n        font-family: 'Raleway', sans-serif !important;\n        font-weight: 600 !important;\n        text-transform: uppercase !important;\n        font-size: 1.1em !important;\n        letter-spacing: 0.5px !important;\n        cursor: pointer !important;\n        list-style: none !important;\n        position: relative !important;\n        display: flex !important;\n        justify-content: space-between !important;\n        align-items: center !important;\n        transition: background-color 0.3s ease !important;\n    }\n\n    \/* Ocultar la flecha por defecto de details\/summary *\/\n    .dlw-accordion-header::-webkit-details-marker {\n        display: none !important;\n    }\n\n    \/* Icono + \/ x personalizado *\/\n    .dlw-accordion-header::after {\n        content: '+' !important;\n        font-size: 1.8em !important;\n        line-height: 1 !important;\n        color: var(--dlw-blue-cyan) !important;\n        transition: transform 0.3s ease !important;\n    }\n\n    .dlw-accordion[open] .dlw-accordion-header::after {\n        transform: rotate(45deg) !important; \/* Gira el + para que parezca una x *\/\n    }\n\n    .dlw-accordion[open] .dlw-accordion-header {\n        border-bottom: 2px solid var(--dlw-blue-cyan) !important;\n    }\n\n    \/* Ajuste de la tabla dentro del acorde\u00f3n *\/\n    .dlw-accordion-content .dlw-table {\n        margin-bottom: 0 !important;\n        box-shadow: none !important;\n        border-radius: 0 !important;\n        border-top: none !important;\n    }\n\n    \/* Responsive *\/\n    @media (max-width: 768px) {\n        .dlw-lead-box { padding: 1.8em !important; }\n        .dlw-check-list { grid-template-columns: 1fr !important; padding: 1.5em !important; }\n        .dlw-prod-img { max-width: 100% !important; }\n        \n        \/* Tablas Responsive *\/\n        .dlw-table, .dlw-table thead, .dlw-table tbody, .dlw-table th, .dlw-table td, .dlw-table tr { display: block !important; }\n        .dlw-table thead tr { position: absolute !important; top: -9999px !important; left: -9999px !important; }\n        .dlw-table tr { border-bottom: 2px solid var(--dlw-blue-cyan) !important; margin-bottom: 15px !important; }\n        .dlw-table td { border: none !important; position: relative !important; padding-left: 45% !important; }\n        .dlw-table td::before { position: absolute !important; top: 15px !important; left: 15px !important; width: 40% !important; white-space: nowrap !important; font-weight: bold !important; color: var(--dlw-blue-dark) !important; font-size: 0.9em !important; text-transform: uppercase !important; }\n        .dlw-table td:nth-of-type(1)::before { content: \"Reference\" !important; }\n        .dlw-table td:nth-of-type(2)::before { content: \"Description\" !important; }\n    }\n<\/style>\n\n<!-- ==========================================\n     CONTENIDO UNIFICADO Y BLINDADO\n     ========================================== -->\n<div class=\"dlw-prod-wrapper\">\n\n    <!-- Descripci\u00f3n Corta (Lead Box) -->\n    <div class=\"dlw-lead-box\">\n        <p>Devyser BRCA PALB2 NGS is a fast and robust NGS solution designed for the detection of genetic variants in the BRCA1, BRCA2, and PALB2 genes. It offers comprehensive and uniform coverage of all coding exons and exon\/intron junctions of both genes. In addition, it includes the detection of single nucleotide variants (SNVs), insertions\/deletions (Indels), and copy number variations (CNVs), in both germline and somatic contexts.<\/p>\n    <\/div>\n\n    <!-- Aspectos clave -->\n    <h2>Key Features<\/h2>\n    <div class=\"dlw-check-list\">\n        <div class=\"dlw-check-item\">\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n            <span>Comprehensive variant detection: Identifies relevant genetic variants in the BRCA1, BRCA2, and PALB2 genes, including CNVs.<\/span>\n        <\/div>\n        <div class=\"dlw-check-item\">\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n            <span>Fast workflow: optimized for rapid results with same-day library preparation and less than 45 minutes of hands-on time.<\/span>\n        <\/div>\n        <div class=\"dlw-check-item\">\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n            <span>A single workflow is easily and effectively applied to two applications: germline and somatic analysis.<\/span>\n        <\/div>\n        <div class=\"dlw-check-item\">\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n            <span>Dedicated software: Provides automated, user-friendly analysis, with options for batch export and efficient variant analysis without the need for bioinformatics expertise.<\/span>\n        <\/div>\n    <\/div>\n\n    <!-- Imagen 1 Actualizada -->\n    <img decoding=\"async\" src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/04\/Imagen1-6.webp\" alt=\"Devyser BRCA PALB2 NGS Workflow\" class=\"dlw-prod-img\" title=\"\">\n\n    <!-- P\u00fablico\/usuario previsto -->\n    <h2>Intended Audience \/ User<\/h2>\n    <p>Ideal for laboratories that need to comprehensively analyze the BRCA1, BRCA2, and PALB2 genes in a streamlined workflow. The targeted sequencing approach and uniform coverage of target regions maximize the retrieval of relevant data in every sequencing run.<\/p>\n\n    <!-- Beneficios -->\n    <h2>Benefits<\/h2>\n    <div class=\"dlw-list\">\n        <span class=\"dlw-list-item\">Streamlined workflow: easy to implement and suitable for laboratories with varying sample volume needs.<\/span>\n        <span class=\"dlw-list-item\">Ready-to-use reagents, ensuring a reproducible process and reducing the risk of sample mix-ups or contamination.<\/span>\n        <span class=\"dlw-list-item\">Compatible with germline and somatic analysis under the same workflow.<\/span>\n        <span class=\"dlw-list-item\">Intuitive software: facilitates the interpretation of obtained data, reducing the need for bioinformatics intervention.<\/span>\n    <\/div>\n\n    <!-- Consideraciones adicionales -->\n    <h2>Additional Considerations<\/h2>\n    <div class=\"dlw-list\">\n        <span class=\"dlw-list-item\">Starting material: Human genomic DNA extracted from whole blood or FFPE tissue.<\/span>\n        <span class=\"dlw-list-item\">In FFPE samples, it is necessary to previously evaluate concentration and integrity, as initial sample quality can compromise the assay results.<\/span>\n    <\/div>\n\n    <!-- Detalles de Presentaci\u00f3n -->\n    <h2>Ordering Information<\/h2>\n\n    <details class=\"dlw-accordion\">\n        <summary class=\"dlw-accordion-header\">Devyser BRCA PALB2 Kits<\/summary>\n        <div class=\"dlw-accordion-content\">\n            <table class=\"dlw-table\">\n                <tbody>\n                    <tr>\n                        <td width=\"30%\" class=\"dlw-ref-code\">8-A408-8<\/td>\n                        <td width=\"70%\">8 tests<\/td>\n                    <\/tr>\n                    <tr>\n                        <td class=\"dlw-ref-code\">8-A408-24<\/td>\n                        <td>24 tests<\/td>\n                    <\/tr>\n                    <tr>\n                        <td class=\"dlw-ref-code\">8-A408-96<\/td>\n                        <td>96 tests<\/td>\n                    <\/tr>\n                <\/tbody>\n            <\/table>\n        <\/div>\n    <\/details>\n\n    <details class=\"dlw-accordion\">\n        <summary class=\"dlw-accordion-header\">Purification, Sequencing, and Analysis<\/summary>\n        <div class=\"dlw-accordion-content\">\n            <table class=\"dlw-table\">\n                <tbody>\n                    <tr>\n                        <td width=\"30%\" class=\"dlw-ref-code\">Purification<\/td>\n                        <td width=\"70%\">Devyser Library Clean (8-A204) for library purification.<\/td>\n                    <\/tr>\n                    <tr>\n                        <td class=\"dlw-ref-code\">Sequencing<\/td>\n                        <td>Sequencing on Illumina MiSeq.<\/td>\n                    <\/tr>\n                    <tr>\n                        <td class=\"dlw-ref-code\">Analysis<\/td>\n                        <td>Analysis in Amplicon Suite with Devyser BRCA PALB2 pipeline.<\/td>\n                    <\/tr>\n                <\/tbody>\n            <\/table>\n        <\/div>\n    <\/details>\n\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Devyser BRCA PALB2 NGS is a fast and robust NGS solution designed for the detection of genetic variants in the BRCA1, BRCA2, and PALB2 genes. It offers comprehensive and uniform coverage of all coding exons and exon\/intron junctions of both genes. In addition, it includes the detection of single nucleotide variants (SNVs), insertions\/deletions (Indels), and [&hellip;]<\/p>\n","protected":false},"featured_media":27215,"template":"","tecnologias":[36],"marcas":[514],"familias":[347,445,283,441],"class_list":["post-27222","productos","type-productos","status-publish","has-post-thumbnail","hentry","tecnologias-next-generation-sequencing-ngs","marcas-dvysr_en","familias-solid-tumor","familias-hereditary_cancer","familias-molecular-genetics","familias-targeted_study_of_specific_pathologies"],"_links":{"self":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/27222","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos"}],"about":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/types\/productos"}],"version-history":[{"count":2,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/27222\/revisions"}],"predecessor-version":[{"id":27225,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/27222\/revisions\/27225"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media\/27215"}],"wp:attachment":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media?parent=27222"}],"wp:term":[{"taxonomy":"tecnologias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/tecnologias?post=27222"},{"taxonomy":"marcas","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/marcas?post=27222"},{"taxonomy":"familias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/familias?post=27222"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}