{"id":27323,"date":"2026-05-14T11:56:25","date_gmt":"2026-05-14T11:56:25","guid":{"rendered":"https:\/\/www.dlongwood.com\/?post_type=productos&#038;p=27323"},"modified":"2026-05-14T12:01:07","modified_gmt":"2026-05-14T12:01:07","slug":"cellscape-precise-spatial-proteomics","status":"publish","type":"productos","link":"https:\/\/www.dlongwood.com\/en\/product-catalog\/cellscape-precise-spatial-proteomics\/","title":{"rendered":"CellScape&#x2122; Precise Spatial Proteomics"},"content":{"rendered":"\n<!-- Bloque de Estilos Scoped (Aislados, Blindados y Escalados a 14px) -->\n<style>\n    \/* Importaci\u00f3n de fuentes corporativas *\/\n    @import url('https:\/\/fonts.googleapis.com\/css2?family=Playfair+Display:ital,wght@0,400;0,700;1,400&family=Raleway:wght@300;400;500;600;700&display=swap');\n\n    \/* Contenedor Principal Aislado *\/\n    .dlw-prod-wrapper {\n        font-family: 'Raleway', sans-serif !important;\n        color: #000000 !important;\n        line-height: 1.6 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(max-width: 768px) {\n        .dlw-lead-box { padding: 1.8em !important; }\n        .dlw-check-list { grid-template-columns: 1fr !important; padding: 1.5em !important; }\n        .dlw-prod-img { max-width: 100% !important; }\n        .dlw-prod-wrapper a.dlw-btn { width: 100% !important; box-sizing: border-box !important; text-align: center !important; }\n    }\n<\/style>\n\n<!-- ==========================================\n     CONTENIDO UNIFICADO Y BLINDADO\n     ========================================== -->\n<div class=\"dlw-prod-wrapper\">\n\n    <!-- Descripci\u00f3n Corta (Lead Box) -->\n    <div class=\"dlw-lead-box\">\n        <p>The CellScape&#x2122; Precise Spatial Proteomics platform is an optimized multiplexed immunofluorescence (mIF) solution for high-plex spatial protein detection and quantitative phenotyping. By combining an advanced imaging system with integrated microfluidics for &#8220;walk-away&#8221; automation, and an open ecosystem based on simple chemistry and robust throughput, the CellScape platform accelerates biological discovery and translational research across multiple disciplines.<\/p>\n    <\/div>\n\n    <!-- Imagen 1 -->\n    <img decoding=\"async\" src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/05\/Imagen1-1.webp\" alt=\"CellScape Platform\" class=\"dlw-prod-img\" title=\"\">\n\n    <!-- Aspectos Clave -->\n    <h2>Key Features<\/h2>\n    \n    <div class=\"dlw-check-list\">\n        <div class=\"dlw-check-item\">\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n            <span>High-resolution imaging with 182 nm\/pixel digital sampling.<\/span>\n        <\/div>\n        <div class=\"dlw-check-item\">\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n            <span>Spatial proteomics at single-cell and subcellular levels.<\/span>\n        <\/div>\n        <div class=\"dlw-check-item\">\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n            <span>High dynamic range (HDR) imaging for accurate detection of low- and high-expressing biomarkers.<\/span>\n        <\/div>\n        <div class=\"dlw-check-item\">\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n            <span>Whole-slide imaging across tissue areas >700 mm\u00b2.<\/span>\n        <\/div>\n        <div class=\"dlw-check-item\">\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n            <span>&#8220;Walk-away&#8221; automated workflow with integrated microfluidics.<\/span>\n        <\/div>\n        <div class=\"dlw-check-item\">\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n            <span>Open assay design using commercially available fluorophore-conjugated primary antibodies.<\/span>\n        <\/div>\n        <div class=\"dlw-check-item\">\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n            <span>Compatibility with over 6,000 validated antibodies.<\/span>\n        <\/div>\n        <div class=\"dlw-check-item\">\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n            <span>Scalable assays through iterative staining and imaging cycles.<\/span>\n        <\/div>\n        <div class=\"dlw-check-item\">\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n            <span>EpicIF&#x2122; signal-removal chemistry to gently erase fluorescence while preserving tissue.<\/span>\n        <\/div>\n        <div class=\"dlw-check-item\">\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n            <span>Standard OME-TIFF outputs compatible with common image analysis software.<\/span>\n        <\/div>\n        <div class=\"dlw-check-item\">\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n            <span>Compatible with FFPE tissues, fresh frozen tissues, and cell suspensions.<\/span>\n        <\/div>\n    <\/div>\n\n    <!-- \u00bfC\u00f3mo funciona? -->\n    <h2>How does it work?<\/h2>\n    <p>CellScape&#x2122; uses an iterative workflow based on cyclic immunofluorescence. Samples are stained with directly conjugated fluorescent antibodies, high-resolution images are acquired, and then subjected to EpicIF&#x2122; signal-removal chemistry to erase fluorescent signals without damaging tissue morphology or epitopes. The process can be repeated multiple times to generate highly multiplexed spatial proteomics datasets from the same sample.<\/p>\n    \n    <p>The platform integrates:<\/p>\n    <div class=\"dlw-list\">\n        <span class=\"dlw-list-item\">Automated microfluidics for reagent dispensing.<\/span>\n        <span class=\"dlw-list-item\">HDR optical imaging for quantitative biomarker detection.<\/span>\n        <span class=\"dlw-list-item\">Automatic image alignment between cycles.<\/span>\n        <span class=\"dlw-list-item\">Flexible assay expansion with additional biomarkers at any stage of the experiment.<\/span>\n    <\/div>\n\n    <p>This workflow enables precise quantitative phenotyping and spatial analysis of complex tissues at single-cell resolution.<\/p>\n    <p>Simple and straightforward workflow from sample preparation to image generation:<\/p>\n\n    <!-- Imagen 2 -->\n    <img decoding=\"async\" src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/05\/Imagen2-eng-1.webp\" alt=\"CellScape Workflow\" class=\"dlw-prod-img\" title=\"\">\n\n    <!-- Aplicaciones -->\n    <h2>Applications<\/h2>\n    <div class=\"dlw-list\">\n        <span class=\"dlw-list-item\">Spatial profiling of tumor microenvironments.<\/span>\n        <span class=\"dlw-list-item\">Immuno-oncology research.<\/span>\n        <span class=\"dlw-list-item\">Biomarker discovery and validation.<\/span>\n        <span class=\"dlw-list-item\">Translational and clinical research.<\/span>\n        <span class=\"dlw-list-item\">Immune cell phenotyping.<\/span>\n        <span class=\"dlw-list-item\">Neuroscience research.<\/span>\n        <span class=\"dlw-list-item\">Infectious disease studies.<\/span>\n        <span class=\"dlw-list-item\">Cell-cell interaction analysis.<\/span>\n        <span class=\"dlw-list-item\">Longitudinal and hypothesis-driven studies in spatial biology.<\/span>\n        <span class=\"dlw-list-item\">Multi-omics workflows integrating transcriptomics and proteomics.<\/span>\n    <\/div>\n\n    <!-- Paneles disponibles -->\n    <h2>Available Panels: VistaPlex&#x2122; Assay Kits<\/h2>\n    <p>Multiplexed panels of pre-validated antibodies designed for rapid implementation and streamlined assay development.<\/p>\n\n    <!-- Imagen 3 con enlace -->\n    <div style=\"text-align: center !important; width: 100% !important; margin: 2em 0 !important;\">\n        <a href=\"https:\/\/brukerspatialbiology.com\/products\/cellscape-precise-spatial-proteomics\/vistaplex-multiplexing-assay-kits\/\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"display: inline-block !important; max-width: 400px !important; width: 100% !important;\">\n            <img decoding=\"async\" src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/05\/Imagen3.webp\" alt=\"VistaPlex Assay Kits\" class=\"dlw-prod-img\" style=\"margin: 0 auto !important;\" title=\"\">\n        <\/a>\n    <\/div>\n\n    <!-- CellScape Data Explorer -->\n    <h2>CellScape&#x2122; Data Explorer<\/h2>\n    <p>CellScape&#x2122; Data Explorer is an interactive browser-based platform that allows you to explore real high-plex spatial proteomics datasets generated with CellScape&#x2122; and VistaPlex&#x2122; Assay kits.<\/p>\n    \n    <p>The Data Explorer enables:<\/p>\n    <div class=\"dlw-list\">\n        <span class=\"dlw-list-item\">Interactive visualization of spatial proteomics datasets directly in the browser.<\/span>\n        <span class=\"dlw-list-item\">Smooth zooming from full tissue architecture to single-cell details.<\/span>\n        <span class=\"dlw-list-item\">Individual marker visualization and overlap analysis.<\/span>\n        <span class=\"dlw-list-item\">Exploration of tissue regions at multiple spatial scales.<\/span>\n        <span class=\"dlw-list-item\">Phenotype overlay and segmentation for cellular organization analysis.<\/span>\n        <span class=\"dlw-list-item\">Evaluation of staining specificity and marker localization.<\/span>\n        <span class=\"dlw-list-item\">Assessment of spatial relationships within tissues.<\/span>\n    <\/div>\n\n    <p>The representative datasets demonstrate the platform&#8217;s ability to combine:<\/p>\n    <div class=\"dlw-list\">\n        <span class=\"dlw-list-item\">Best-in-class spatial resolution.<\/span>\n        <span class=\"dlw-list-item\">High dynamic range imaging.<\/span>\n        <span class=\"dlw-list-item\">Quantitative biomarker analysis.<\/span>\n        <span class=\"dlw-list-item\">Broad tissue coverage with cell-level detail.<\/span>\n    <\/div>\n\n    <p>Commercially available image datasets:<\/p>\n    <div class=\"dlw-list\">\n        <span class=\"dlw-list-item dlw-interactive-list-item\"><a href=\"https:\/\/minerva-cellscape-bc-vistaplex.s3.us-east-2.amazonaws.com\/index.html#s=0#w=0#g=0#m=-1#a=-100_-100#v=0.5327_0.4254_0.5#o=-100_-100_1_1#p=Q#r=100\" target=\"_blank\" rel=\"noopener noreferrer\">Human FFPE Breast Cancer<\/a><\/span>\n        <span class=\"dlw-list-item dlw-interactive-list-item\"><a href=\"https:\/\/minerva-cellscape-crc-vistaplex.s3.us-east-2.amazonaws.com\/index.html#s=0#w=0#g=0#m=-1#a=-100_-100#v=0.4796_0.4245_0.5#o=-100_-100_1_1#p=Q#r=100\" target=\"_blank\" rel=\"noopener noreferrer\">Human FFPE Colorectal Cancer<\/a><\/span>\n        <span class=\"dlw-list-item dlw-interactive-list-item\"><a href=\"https:\/\/minerva-cellscape-hnc-vistaplex.s3.us-east-2.amazonaws.com\/index.html#s=0#w=0#g=0#m=-1#a=-100_-100#v=0.4792_0.4534_0.4447#o=-100_-100_1_1#p=Q#r=100\" target=\"_blank\" rel=\"noopener noreferrer\">Human FFPE Head &#038; Neck Cancer<\/a><\/span>\n        <span class=\"dlw-list-item dlw-interactive-list-item\"><a href=\"https:\/\/minerva-cellscape-mmsc-vistaplex.s3.us-east-2.amazonaws.com\/index.html#s=0#w=0#g=0#m=-1#a=-100_-100#v=0.4623_0.367_0.5017#o=-100_-100_1_1#p=Q#r=100\" target=\"_blank\" rel=\"noopener noreferrer\">Human FFPE Melanoma<\/a><\/span>\n    <\/div>\n\n    <p>CellScape&#x2122; Data Explorer provides a hands-on preview of the depth, quality, and biological insights that the CellScape&#x2122; platform can generate across multiple sample types and research applications.<\/p>\n\n    <!-- Imagen 4 -->\n    <img decoding=\"async\" src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/05\/Imagen4.webp\" alt=\"CellScape Data Explorer\" class=\"dlw-prod-img\" title=\"\">\n\n    <!-- Bot\u00f3n CTA Final -->\n    <div class=\"dlw-btn-wrapper\">\n        <a href=\"https:\/\/brukerspatialbiology.com\/products\/cellscape-precise-spatial-proteomics\/cellscape-psp-overview\/?utm_source=chatgpt.com\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"dlw-btn\">\n            Learn more: CellScape&#x2122; Precise Spatial Proteomics Overview\n        <\/a>\n    <\/div>\n\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>The CellScape&#x2122; Precise Spatial Proteomics platform is an optimized multiplexed immunofluorescence (mIF) solution for high-plex spatial protein detection and quantitative phenotyping. 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