{"id":27767,"date":"2026-06-17T11:24:04","date_gmt":"2026-06-17T11:24:04","guid":{"rendered":"https:\/\/www.dlongwood.com\/?post_type=productos&#038;p=27767"},"modified":"2026-06-17T11:45:33","modified_gmt":"2026-06-17T11:45:33","slug":"hedera-profiling-1-ffpe-test-panel-hp1","status":"publish","type":"productos","link":"https:\/\/www.dlongwood.com\/en\/product-catalog\/hedera-profiling-1-ffpe-test-panel-hp1\/","title":{"rendered":"Hedera Profiling 1 FFPE Test Panel (HP1)"},"content":{"rendered":"\n<!-- Scoped Styles Block (Isolated, Shielded, and Scaled to 14px) -->\n\n<style>\n\n    \/* Corporate font import *\/\n\n    @import url('https:\/\/fonts.googleapis.com\/css2?family=Playfair+Display:ital,wght@0,400;0,700;1,400&family=Raleway:wght@300;400;500;600;700&display=swap');\n\n\n\n    \/* Main Isolated Container *\/\n\n    .dlw-prod-wrapper {\n\n        font-family: 'Raleway', sans-serif !important;\n\n        color: #000000 !important;\n\n        line-height: 1.6 !important;\n\n        background-color: transparent !important;\n\n        padding: 0 !important;\n\n        max-width: 100% !important;\n\n        text-align: left !important;\n\n        display: block !important;\n\n        font-size: 14px !important; \/* ANCHOR: Ignores defective root size from Bricks *\/\n\n    }\n\n\n\n    \/* Local CSS Variables *\/\n\n    .dlw-prod-wrapper {\n\n        --dlw-blue-dark: #003a70;\n\n        --dlw-blue-cyan: #00a1e0;\n\n        --dlw-light-bg: #f9fbfd;\n\n        --dlw-grey-bg: #f4f6f8;\n\n        --dlw-border: #e1e8f0;\n\n        --dlw-grey: #939598;\n\n    }\n\n\n\n    \/* H2 Headings *\/\n\n    .dlw-prod-wrapper h2 {\n\n        font-family: 'Playfair Display', serif !important;\n\n        color: var(--dlw-blue-dark) !important;\n\n        margin-top: 2em !important;\n\n        margin-bottom: 0.8em !important;\n\n        font-size: 1.8em !important;\n\n        font-weight: 700 !important;\n\n        border-bottom: 2px solid var(--dlw-border) !important;\n\n        padding-bottom: 10px !important;\n\n        display: block !important;\n\n    }\n\n\n\n    \/* H3 Headings *\/\n\n    .dlw-prod-wrapper h3 {\n\n        font-family: 'Playfair Display', serif !important;\n\n        color: var(--dlw-blue-cyan) !important;\n\n        margin-top: 1.5em !important;\n\n        margin-bottom: 0.5em !important;\n\n        font-size: 1.4em !important;\n\n        font-weight: 700 !important;\n\n        display: block !important;\n\n    }\n\n\n\n    \/* Standard paragraphs *\/\n\n    .dlw-prod-wrapper p {\n\n        font-weight: 400 !important;\n\n        margin-bottom: 1.2em !important;\n\n        text-align: justify !important;\n\n        font-size: 1.25em !important;\n\n        color: #333333 !important;\n\n    }\n\n\n\n    \/* Corporate bold text *\/\n\n    .dlw-prod-wrapper strong {\n\n        color: var(--dlw-blue-dark) !important;\n\n        font-weight: 700 !important;\n\n    }\n\n\n\n    \/* Lead \/ Short Description (Corporate Blue Box) *\/\n\n    .dlw-lead-box {\n\n        background-color: var(--dlw-blue-dark) !important;\n\n        color: #ffffff !important;\n\n        padding: 2.5em 3em !important;\n\n        margin-bottom: 2.5em !important;\n\n        border-radius: 8px !important;\n\n        box-shadow: 0 6px 25px rgba(0, 58, 112, 0.2) !important;\n\n    }\n\n\n\n    .dlw-lead-box p {\n\n        color: #ffffff !important;\n\n        font-size: 1.35em !important;\n\n        font-weight: 500 !important;\n\n        margin-bottom: 0 !important;\n\n        text-align: left !important;\n\n    }\n\n\n\n    \/* Single inserted images (centered) *\/\n\n    .dlw-prod-img {\n\n        width: auto !important;\n\n        max-width: 90% !important;\n\n        height: auto !important;\n\n        display: block !important;\n\n        margin: 2.5em auto !important;\n\n        margin-left: auto !important;\n\n        margin-right: auto !important;\n\n        float: none !important;\n\n        border-radius: 6px !important;\n\n        box-shadow: none !important;\n\n        transition: transform 0.4s cubic-bezier(0.165, 0.84, 0.44, 1) !important;\n\n        cursor: zoom-in !important;\n\n    }\n\n\n\n    .dlw-prod-img:hover {\n\n        transform: scale(1.03) !important;\n\n    }\n\n\n\n    \/* Standard lists (bullets) *\/\n\n    .dlw-list {\n\n        display: flex !important;\n\n        flex-direction: column !important;\n\n        margin-bottom: 2em !important;\n\n        padding-left: 0 !important;\n\n    }\n\n\n\n    .dlw-list-item {\n\n        position: relative !important;\n\n        padding-left: 1.5em !important;\n\n        margin-bottom: 0.8em !important;\n\n        text-align: left !important;\n\n        font-size: 1.25em !important;\n\n        color: #333333 !important;\n\n        display: block !important;\n\n    }\n\n\n\n    .dlw-list-item::before {\n\n        content: \"\u2022\" !important;\n\n        position: absolute !important;\n\n        left: 0 !important;\n\n        color: var(--dlw-blue-cyan) !important;\n\n        font-weight: bold !important;\n\n        font-size: 1.2em !important;\n\n        top: -2px !important;\n\n    }\n\n\n\n    \/* Nested sub-lists *\/\n\n    .dlw-sub-list {\n\n        margin-top: 0.5em !important;\n\n        margin-bottom: 0.5em !important;\n\n        padding-left: 1.5em !important;\n\n    }\n\n\n\n    .dlw-sub-list-item {\n\n        position: relative !important;\n\n        padding-left: 1.2em !important;\n\n        margin-bottom: 0.4em !important;\n\n        font-size: 0.95em !important;\n\n        color: #555555 !important;\n\n        display: block !important;\n\n    }\n\n\n\n    .dlw-sub-list-item::before {\n\n        content: \"-\" !important;\n\n        position: absolute !important;\n\n        left: 0 !important;\n\n        color: var(--dlw-grey) !important;\n\n        font-weight: bold !important;\n\n    }\n\n\n\n    \/* Check lists (Key Features) *\/\n\n    .dlw-check-list {\n\n        display: grid !important;\n\n        grid-template-columns: 1fr 1fr !important;\n\n        gap: 1.5em 2em !important;\n\n        margin: 2em 0 !important;\n\n        background-color: var(--dlw-light-bg) !important;\n\n        padding: 2.5em !important;\n\n        border-radius: 8px !important;\n\n        border-left: 6px solid var(--dlw-blue-cyan) !important;\n\n    }\n\n\n\n    .dlw-check-item {\n\n        display: flex !important;\n\n        align-items: flex-start !important;\n\n        gap: 12px !important;\n\n        font-size: 1.2em !important;\n\n        color: #333333 !important;\n\n        line-height: 1.4 !important;\n\n    }\n\n\n\n    .dlw-check-icon {\n\n        width: 24px !important;\n\n        height: 24px !important;\n\n        min-width: 24px !important;\n\n        fill: var(--dlw-blue-cyan) !important;\n\n        margin-top: 2px !important;\n\n        flex-shrink: 0 !important;\n\n    }\n\n    \n\n    .dlw-check-item:last-child:nth-child(odd) {\n\n        grid-column: 1 \/ -1 !important;\n\n    }\n\n\n\n    \/* Corporate Tables (References) *\/\n\n    .dlw-table {\n\n        width: 100% !important;\n\n        border-collapse: collapse !important;\n\n        margin-bottom: 2.5em !important;\n\n        background-color: #ffffff !important;\n\n        box-shadow: 0 2px 10px rgba(0,0,0,0.03) !important;\n\n        border-radius: 6px !important;\n\n        overflow: hidden !important;\n\n    }\n\n\n\n    .dlw-table th {\n\n        background-color: var(--dlw-blue-dark) !important;\n\n        color: #ffffff !important;\n\n        text-align: left !important;\n\n        padding: 15px 20px !important;\n\n        font-family: 'Raleway', sans-serif !important;\n\n        font-weight: 600 !important;\n\n        text-transform: uppercase !important;\n\n        font-size: 1.1em !important;\n\n        letter-spacing: 0.5px !important;\n\n    }\n\n\n\n    .dlw-table td {\n\n        padding: 15px 20px !important;\n\n        border-bottom: 1px solid var(--dlw-border) !important;\n\n        vertical-align: middle !important;\n\n        font-size: 1.2em !important;\n\n        color: #333333 !important;\n\n    }\n\n    \n\n    .dlw-table tr:hover td {\n\n        background-color: var(--dlw-light-bg) !important;\n\n    }\n\n\n\n    .dlw-table tr:last-child td {\n\n        border-bottom: 2px solid var(--dlw-blue-cyan) !important;\n\n    }\n\n\n\n    .dlw-ref-code {\n\n        font-family: 'Courier New', Courier, monospace !important;\n\n        font-weight: 700 !important;\n\n        color: var(--dlw-blue-dark) !important;\n\n    }\n\n\n\n    \/* Accordions *\/\n\n    .dlw-accordion {\n\n        background-color: #ffffff !important;\n\n        border: 1px solid var(--dlw-border) !important;\n\n        border-radius: 6px !important;\n\n        margin-bottom: 1.5em !important;\n\n        overflow: hidden !important;\n\n        transition: all 0.3s ease !important;\n\n    }\n\n\n\n    .dlw-accordion-header {\n\n        background-color: var(--dlw-blue-dark) !important;\n\n        color: #ffffff !important;\n\n        padding: 15px 20px !important;\n\n        font-family: 'Raleway', sans-serif !important;\n\n        font-weight: 600 !important;\n\n        text-transform: uppercase !important;\n\n        font-size: 1.1em !important;\n\n        letter-spacing: 0.5px !important;\n\n        cursor: pointer !important;\n\n        list-style: none !important;\n\n        position: relative !important;\n\n        display: flex !important;\n\n        justify-content: space-between !important;\n\n        align-items: center !important;\n\n        transition: background-color 0.3s ease !important;\n\n    }\n\n\n\n    \/* Hide default details\/summary arrow *\/\n\n    .dlw-accordion-header::-webkit-details-marker {\n\n        display: none !important;\n\n    }\n\n\n\n    \/* Custom + \/ x icon *\/\n\n    .dlw-accordion-header::after {\n\n        content: '+' !important;\n\n        font-size: 1.8em !important;\n\n        line-height: 1 !important;\n\n        color: var(--dlw-blue-cyan) !important;\n\n        transition: transform 0.3s ease !important;\n\n    }\n\n\n\n    .dlw-accordion[open] .dlw-accordion-header::after {\n\n        transform: rotate(45deg) !important;\n\n    }\n\n\n\n    .dlw-accordion[open] .dlw-accordion-header {\n\n        border-bottom: 2px solid var(--dlw-blue-cyan) !important;\n\n    }\n\n\n\n    \/* Adjustment for lists\/tables inside accordion *\/\n\n    .dlw-accordion-content {\n\n        padding: 20px !important;\n\n        background-color: #ffffff !important;\n\n    }\n\n\n\n    .dlw-accordion-content .dlw-table {\n\n        margin-bottom: 0 !important;\n\n        box-shadow: none !important;\n\n        border-radius: 0 !important;\n\n        border-top: none !important;\n\n    }\n\n\n\n    .dlw-accordion-content .dlw-list {\n\n        margin-bottom: 0 !important;\n\n    }\n\n    \n\n    .dlw-accordion-content p {\n\n        margin-bottom: 0 !important;\n\n    }\n\n\n\n    \/* Modal \/ Lightbox *\/\n\n    .dlw-modal {\n\n        display: none;\n\n        position: fixed !important;\n\n        z-index: 999999 !important;\n\n        left: 0 !important;\n\n        top: 0 !important;\n\n        width: 100vw !important;\n\n        height: 100vh !important;\n\n        background-color: rgba(0, 20, 40, 0.85) !important;\n\n        backdrop-filter: blur(5px) !important;\n\n        align-items: center !important;\n\n        justify-content: center !important;\n\n    }\n\n\n\n    .dlw-modal.dlw-active {\n\n        display: flex !important;\n\n        animation: dlw-fade-in 0.3s ease-out forwards;\n\n    }\n\n\n\n    @keyframes dlw-fade-in {\n\n        from { opacity: 0; }\n\n        to { opacity: 1; }\n\n    }\n\n\n\n    .dlw-modal-img {\n\n        max-width: 90vw !important;\n\n        max-height: 90vh !important;\n\n        width: auto !important;\n\n        height: auto !important;\n\n        border-radius: 6px !important;\n\n        box-shadow: 0 10px 40px rgba(0,0,0,0.5) !important;\n\n        object-fit: contain !important;\n\n    }\n\n\n\n    .dlw-modal-close {\n\n        position: absolute !important;\n\n        top: 25px !important;\n\n        right: 35px !important;\n\n        color: #ffffff !important;\n\n        font-size: 45px !important;\n\n        font-weight: 300 !important;\n\n        cursor: pointer !important;\n\n        transition: color 0.3s ease !important;\n\n        line-height: 1 !important;\n\n        z-index: 9999999 !important;\n\n    }\n\n\n\n    .dlw-modal-close:hover {\n\n        color: var(--dlw-blue-cyan) !important;\n\n    }\n\n\n\n    \/* Responsive *\/\n\n    @media (max-width: 768px) {\n\n        .dlw-lead-box { padding: 1.8em !important; }\n\n        .dlw-check-list { grid-template-columns: 1fr !important; padding: 1.5em !important; }\n\n        .dlw-prod-img { max-width: 100% !important; }\n\n        \n\n        \/* Responsive Tables *\/\n\n        .dlw-table, .dlw-table thead, .dlw-table tbody, .dlw-table th, .dlw-table td, .dlw-table tr { display: block !important; }\n\n        .dlw-table thead tr { position: absolute !important; top: -9999px !important; left: -9999px !important; }\n\n        .dlw-table tr { border-bottom: 2px solid var(--dlw-blue-cyan) !important; margin-bottom: 15px !important; }\n\n        .dlw-table td { border: none !important; position: relative !important; padding-left: 45% !important; }\n\n        .dlw-table td::before { position: absolute !important; top: 15px !important; left: 15px !important; width: 40% !important; white-space: nowrap !important; font-weight: bold !important; color: var(--dlw-blue-dark) !important; font-size: 0.9em !important; text-transform: uppercase !important; }\n\n        .dlw-table td:nth-of-type(1)::before { content: \"Reference\" !important; }\n\n        .dlw-table td:nth-of-type(2)::before { content: \"Description\" !important; }\n\n    }\n\n<\/style>\n\n\n\n<!-- ==========================================\n\n     UNIFIED AND SHIELDED CONTENT\n\n     ========================================== -->\n\n<div class=\"dlw-prod-wrapper\">\n\n\n\n    <!-- Short Description (Lead Box) -->\n\n    <div class=\"dlw-lead-box\">\n\n        <p>In\u2011house targeted enrichment NGS panel for pan\u2011cancer solid tumor profiling. It analyzes 115 genes (79 with complete CDS) with ESCAT I, II and III clinical evidence. Includes library preparation through a flexible workflow that allows processing FFPE and cfDNA samples together or separately. Detects SNVs, Indels, CNVs, fusions, structural variants and MSI.<\/p>\n\n    <\/div>\n\n\n\n    <!-- Detailed Description -->\n\n    <h2>Detailed Description<\/h2>\n\n\n\n    <h3>PRINCIPLE OF OPERATION<\/h3>\n\n    <p>End\u2011to\u2011end solution based on hybridisation and capture enrichment chemistry for the analysis of 115 genes (79 with complete CDS). The assay consolidates processing into a single dual workflow: it applies initial enzymatic fragmentation for genomic DNA from FFPE tissue and proceeds directly with cfDNA samples. It stands out for requiring highly competitive minimum inputs of <strong>30 ng<\/strong> and <strong>10 ng<\/strong>, respectively.<\/p>\n\n    <p>The assay allows analysis of SNVs, Indels, copy number variations (CNVs), fusions, structural variants and 119 microsatellite instability (MSI) markers. In addition, it has incorporated specific tumour fraction estimation for cfDNA analyses.<\/p>\n\n    <p><strong>Analytical Sensitivity:<\/strong><\/p>\n\n    <p>\u2022 <strong>FFPE samples:<\/strong> Detects variants with allelic frequencies (VAF) up to 5%.<\/p>\n\n    <p>\u2022 <strong>cfDNA samples (Liquid Biopsy):<\/strong> Detects variants with allelic frequencies (VAF) down to 0.5%.<\/p>\n\n\n\n    <!-- Image 1 -->\n\n    <img decoding=\"async\" src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/06\/Imagen1.webp\" alt=\"Hedera Profiling 1 principle of operation\" class=\"dlw-prod-img\" onclick=\"openDlwModal(this.src)\" title=\"\">\n\n\n\n    <p>Library preparation integrates UMI adapters and UDI primers with duplex consensus reading to maximise data reliability, correcting errors and preventing index hopping. After an overnight 16\u2011hour hybridisation, the system delivers sequencing\u2011ready libraries for Illumina or Element Biosciences platforms in just 2 days, with less than 4 hours of hands\u2011on time and automation option.<\/p>\n\n\n\n    <!-- Image 2 (English) -->\n\n    <img decoding=\"async\" src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/06\/Imagen-2-eng.webp\" alt=\"Hedera Profiling 1 workflow\" class=\"dlw-prod-img\" onclick=\"openDlwModal(this.src)\" title=\"\">\n\n\n\n    <p>The analysis is comprehensively completed through <strong>Hedera Prime (CE\u2011IVDR)<\/strong>, a secondary and tertiary analysis software that automates quality control and variant interpretation, presenting results through specific interfaces optimised for each type of genomic alteration.<\/p>\n\n\n\n    <!-- Image 3 (English) -->\n\n    <img decoding=\"async\" src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/06\/Imagen-3-eng.webp\" alt=\"Hedera Prime software\" class=\"dlw-prod-img\" onclick=\"openDlwModal(this.src)\" title=\"\">\n\n\n\n    <h3>CLINICAL APPLICATIONS<\/h3>\n\n    <p>This tool has been designed for molecular profiling of solid tumours by NGS in oncology research workflows, covering tissue (FFPE) and liquid biopsy (cfDNA) samples. The assay has validated biomarkers in multiple tumour types (non\u2011small cell lung cancer [NSCLC], colorectal, cholangiocarcinoma, gastric, thyroid, breast, prostate, pancreatic, hepatocellular, ovarian, endometrial, urothelial and soft tissue sarcomas). The panel includes genes corresponding to ESCAT I, II and III evidence levels.<\/p>\n\n\n\n    <!-- Image 4 (English) -->\n\n    <img decoding=\"async\" src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/06\/Imagen4-eng.webp\" alt=\"Hedera Profiling 1 clinical applications\" class=\"dlw-prod-img\" onclick=\"openDlwModal(this.src)\" title=\"\">\n\n\n\n    <h3>BENEFITS<\/h3>\n\n    <div class=\"dlw-list\">\n\n        <span class=\"dlw-list-item\">Consolidated workflow for dual processing of FFPE and cfDNA samples.<\/span>\n\n        <span class=\"dlw-list-item\">Comprehensive genomic coverage of SNVs, Indels, CNVs, fusions, structural variants and MSI markers.<\/span>\n\n        <span class=\"dlw-list-item\">Integrated tumour fraction estimation in liquid biopsy samples.<\/span>\n\n        <span class=\"dlw-list-item\">Incorporation of UMI technology and UDI primers for error correction and index hopping prevention.<\/span>\n\n        <span class=\"dlw-list-item\">Performance optimisation with minimum sample inputs of 10 ng (cfDNA) and 30 ng (FFPE).<\/span>\n\n        <span class=\"dlw-list-item\">Validated compatibility for sequencing runs on Illumina and Element Biosciences AVITI platforms.<\/span>\n\n        <span class=\"dlw-list-item\">Integration of secondary and tertiary bioinformatic analysis through Hedera Prime software with CE\u2011IVDR marking.<\/span>\n\n    <\/div>\n\n\n\n    <h3>INTENDED USER \/ AUDIENCE<\/h3>\n\n    <div class=\"dlw-list\">\n\n        <span class=\"dlw-list-item\">Laboratories and research groups dedicated to the study, diagnosis and monitoring of solid tumours, regardless of whether the starting material is FFPE or Plasma.<\/span>\n\n    <\/div>\n\n\n\n    <!-- Key Features -->\n\n    <h2>Key Features<\/h2>\n\n    \n\n    <div class=\"dlw-check-list\">\n\n        <div class=\"dlw-check-item\">\n\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n\n            <span>Genomic coverage of 115 unique genes (79 with complete CDS) with RUO marking.<\/span>\n\n        <\/div>\n\n        <div class=\"dlw-check-item\">\n\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n\n            <span>Detection of single nucleotide variants (SNVs), insertions\/deletions (Indels), copy number variations (CNVs), fusions, structural variants and 119 microsatellite instability (MSI) markers.<\/span>\n\n        <\/div>\n\n        <div class=\"dlw-check-item\">\n\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n\n            <span>Design focused on pan\u2011cancer solid tumour studies, integrating biomarkers with ESCAT I, II and III clinical evidence levels for multiple indications.<\/span>\n\n        <\/div>\n\n        <div class=\"dlw-check-item\">\n\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n\n            <span>Hybrid capture enrichment for tumour profile generation, integrating UMI adapters and duplex consensus UDI primers for read error correction.<\/span>\n\n        <\/div>\n\n        <div class=\"dlw-check-item\">\n\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n\n            <span>Compatible with tissue (FFPE) and liquid biopsy (cfDNA) samples, offering the flexibility to process mixed pools of both sample types in the same workflow, with minimum input requirements of 30 ng and 10 ng, respectively.<\/span>\n\n        <\/div>\n\n        <div class=\"dlw-check-item\">\n\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n\n            <span>Sequencing processing capability on Illumina and Element Biosciences AVITI systems.<\/span>\n\n        <\/div>\n\n        <div class=\"dlw-check-item\">\n\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n\n            <span>Automated analysis through the Hedera Prime platform, CE\u2011IVDR marked software that centralises secondary quality control and tertiary variant interpretation.<\/span>\n\n        <\/div>\n\n    <\/div>\n\n\n\n    <!-- Presentation Details (Accordions) -->\n\n    <h2>Presentation Details<\/h2>\n\n\n\n    <details class=\"dlw-accordion\">\n\n        <summary class=\"dlw-accordion-header\">Product identification<\/summary>\n\n        <div class=\"dlw-accordion-content\">\n\n            <div class=\"dlw-list\">\n\n                <span class=\"dlw-list-item\">Commercial name: Hedera Profiling 1 FFPE Test Panel (HP1 FFPE), and Hedera Profiling 1 ctDNA Test Panel.<\/span>\n\n                <span class=\"dlw-list-item\">Product type: Bundle solution.<\/span>\n\n                <span class=\"dlw-list-item\">Product family: Assay Enrichment Kit + Hedera Prime Analytics.<\/span>\n\n                <span class=\"dlw-list-item\">Product ID:<\/span>\n\n                <div class=\"dlw-sub-list\">\n\n                    <span class=\"dlw-sub-list-item\">FFPE MANUAL: A48-8TP126IRM<\/span>\n\n                    <span class=\"dlw-sub-list-item\">FFPE AUTOMATION: A48-8TP126IRA<\/span>\n\n                    <span class=\"dlw-sub-list-item\">PLASMA MANUAL: A24-4LP126IRM<\/span>\n\n                <\/div>\n\n                <span class=\"dlw-list-item\">Product version: 1.0.<\/span>\n\n                <span class=\"dlw-list-item\">Sample type: gDNA (FFPE tissue) and cfDNA (liquid biopsy).<\/span>\n\n            <\/div>\n\n        <\/div>\n\n    <\/details>\n\n\n\n    <details class=\"dlw-accordion\">\n\n        <summary class=\"dlw-accordion-header\">Kit contents<\/summary>\n\n        <div class=\"dlw-accordion-content\">\n\n            <div class=\"dlw-list\">\n\n                <span class=\"dlw-list-item\">Library preparation, Indexing, Purification and isolation:<\/span>\n\n                <div class=\"dlw-sub-list\">\n\n                    <span class=\"dlw-sub-list-item\">Reagents and materials for NGS library preparation.<\/span>\n\n                    <span class=\"dlw-sub-list-item\">Reagents for sample indexing.<\/span>\n\n                    <span class=\"dlw-sub-list-item\">Materials for library purification and isolation.<\/span>\n\n                <\/div>\n\n            <\/div>\n\n        <\/div>\n\n    <\/details>\n\n\n\n    <details class=\"dlw-accordion\">\n\n        <summary class=\"dlw-accordion-header\">Required materials (Not included)<\/summary>\n\n        <div class=\"dlw-accordion-content\">\n\n            <div class=\"dlw-list\">\n\n                <span class=\"dlw-list-item\">Quantification and Quality Control (QC): Fluorometric quantification kits and fragment size assessment kits.<\/span>\n\n                <span class=\"dlw-list-item\">Sequencing: Reagents for sequencing runs on Illumina platforms and Illumina PhiX v3 control.<\/span>\n\n            <\/div>\n\n        <\/div>\n\n    <\/details>\n\n\n\n    <!-- Modal Structure (Lightbox) -->\n\n    <div id=\"dlw-image-modal\" class=\"dlw-modal\">\n\n        <span class=\"dlw-modal-close\" onclick=\"closeDlwModal()\">&times;<\/span>\n\n        <img decoding=\"async\" class=\"dlw-modal-img\" id=\"dlw-modal-img-target\" src=\"\" alt=\"\" title=\"\">\n\n    <\/div>\n\n\n\n<\/div>\n\n\n\n<!-- Modal Script (Vanilla JS, no dependencies) -->\n\n<script>\n\n    function openDlwModal(src) {\n\n        var modal = document.getElementById('dlw-image-modal');\n\n        var modalImg = document.getElementById('dlw-modal-img-target');\n\n        modalImg.src = src;\n\n        modal.classList.add('dlw-active');\n\n        document.body.style.overflow = 'hidden'; \/\/ Locks background scroll\n\n    }\n\n\n\n    function closeDlwModal() {\n\n        var modal = document.getElementById('dlw-image-modal');\n\n        modal.classList.remove('dlw-active');\n\n        document.body.style.overflow = 'auto'; \/\/ Restores scroll\n\n    }\n\n\n\n    \/\/ Closes modal if clicking outside the image\n\n    document.getElementById('dlw-image-modal').addEventListener('click', function(e) {\n\n        if (e.target === this) {\n\n            closeDlwModal();\n\n        }\n\n    });\n\n\n\n    \/\/ Closes modal with ESC key\n\n    document.addEventListener('keydown', function(e) {\n\n        if (e.key === \"Escape\" && document.getElementById('dlw-image-modal').classList.contains('dlw-active')) {\n\n            closeDlwModal();\n\n        }\n\n    });\n\n<\/script>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>In\u2011house targeted enrichment NGS panel for pan\u2011cancer solid tumor profiling. It analyzes 115 genes (79 with complete CDS) with ESCAT I, II and III clinical evidence. Includes library preparation through a flexible workflow that allows processing FFPE and cfDNA samples together or separately. Detects SNVs, Indels, CNVs, fusions, structural variants and MSI. Detailed Description PRINCIPLE [&hellip;]<\/p>\n","protected":false},"featured_media":27790,"template":"","tecnologias":[36],"marcas":[249],"familias":[347,459,462],"class_list":["post-27767","productos","type-productos","status-publish","has-post-thumbnail","hentry","tecnologias-next-generation-sequencing-ngs","marcas-hederadx-en","familias-solid-tumor","familias-liquid-biopsy","familias-pan-cancer"],"_links":{"self":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/27767","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos"}],"about":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/types\/productos"}],"version-history":[{"count":1,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/27767\/revisions"}],"predecessor-version":[{"id":27768,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/27767\/revisions\/27768"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media\/27790"}],"wp:attachment":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media?parent=27767"}],"wp:term":[{"taxonomy":"tecnologias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/tecnologias?post=27767"},{"taxonomy":"marcas","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/marcas?post=27767"},{"taxonomy":"familias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/familias?post=27767"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}