{"id":27806,"date":"2026-06-17T11:55:00","date_gmt":"2026-06-17T11:55:00","guid":{"rendered":"https:\/\/www.dlongwood.com\/?post_type=productos&#038;p=27806"},"modified":"2026-06-17T11:57:38","modified_gmt":"2026-06-17T11:57:38","slug":"hedera-profiling-rna-test-panel","status":"publish","type":"productos","link":"https:\/\/www.dlongwood.com\/en\/product-catalog\/hedera-profiling-rna-test-panel\/","title":{"rendered":"Hedera Profiling RNA Test Panel"},"content":{"rendered":"\n<!-- Scoped Styles Block (Isolated, Shielded, and Scaled to 14px) -->\n\n<style>\n\n    \/* Corporate font import *\/\n\n    @import url('https:\/\/fonts.googleapis.com\/css2?family=Playfair+Display:ital,wght@0,400;0,700;1,400&family=Raleway:wght@300;400;500;600;700&display=swap');\n\n\n\n    \/* Main Isolated Container *\/\n\n    .dlw-prod-wrapper {\n\n        font-family: 'Raleway', sans-serif !important;\n\n        color: #000000 !important;\n\n        line-height: 1.6 !important;\n\n        background-color: transparent !important;\n\n        padding: 0 !important;\n\n        max-width: 100% !important;\n\n        text-align: left !important;\n\n        display: block !important;\n\n        font-size: 14px !important; \/* ANCHOR: Ignores defective root size from Bricks *\/\n\n    }\n\n\n\n    \/* Local CSS Variables *\/\n\n    .dlw-prod-wrapper {\n\n        --dlw-blue-dark: #003a70;\n\n        --dlw-blue-cyan: #00a1e0;\n\n        --dlw-light-bg: #f9fbfd;\n\n        --dlw-grey-bg: #f4f6f8;\n\n        --dlw-border: #e1e8f0;\n\n        --dlw-grey: #939598;\n\n    }\n\n\n\n    \/* H2 Headings *\/\n\n    .dlw-prod-wrapper h2 {\n\n        font-family: 'Playfair Display', serif !important;\n\n        color: var(--dlw-blue-dark) !important;\n\n        margin-top: 2em !important;\n\n        margin-bottom: 0.8em !important;\n\n        font-size: 1.8em !important;\n\n        font-weight: 700 !important;\n\n        border-bottom: 2px solid var(--dlw-border) !important;\n\n        padding-bottom: 10px !important;\n\n        display: block !important;\n\n    }\n\n\n\n    \/* H3 Headings *\/\n\n    .dlw-prod-wrapper h3 {\n\n        font-family: 'Playfair Display', serif !important;\n\n        color: var(--dlw-blue-cyan) !important;\n\n        margin-top: 1.5em !important;\n\n        margin-bottom: 0.5em !important;\n\n        font-size: 1.4em !important;\n\n        font-weight: 700 !important;\n\n        display: block !important;\n\n    }\n\n\n\n    \/* Standard paragraphs *\/\n\n    .dlw-prod-wrapper p {\n\n        font-weight: 400 !important;\n\n        margin-bottom: 1.2em !important;\n\n        text-align: justify !important;\n\n        font-size: 1.25em !important;\n\n        color: #333333 !important;\n\n    }\n\n\n\n    \/* Corporate bold text *\/\n\n    .dlw-prod-wrapper strong {\n\n        color: var(--dlw-blue-dark) !important;\n\n        font-weight: 700 !important;\n\n    }\n\n\n\n    \/* Lead \/ Short Description (Corporate Blue Box) *\/\n\n    .dlw-lead-box {\n\n        background-color: var(--dlw-blue-dark) !important;\n\n        color: #ffffff !important;\n\n        padding: 2.5em 3em !important;\n\n        margin-bottom: 2.5em !important;\n\n        border-radius: 8px !important;\n\n        box-shadow: 0 6px 25px rgba(0, 58, 112, 0.2) !important;\n\n    }\n\n\n\n    .dlw-lead-box p {\n\n        color: #ffffff !important;\n\n        font-size: 1.35em !important;\n\n        font-weight: 500 !important;\n\n        margin-bottom: 0 !important;\n\n        text-align: left !important;\n\n    }\n\n\n\n    \/* Single inserted images (centered) *\/\n\n    .dlw-prod-img {\n\n        width: auto !important;\n\n        max-width: 90% !important;\n\n        height: auto !important;\n\n        display: block !important;\n\n        margin: 2.5em auto !important;\n\n        margin-left: auto !important;\n\n        margin-right: auto !important;\n\n        float: none !important;\n\n        border-radius: 6px !important;\n\n        box-shadow: none !important;\n\n        transition: transform 0.4s cubic-bezier(0.165, 0.84, 0.44, 1) !important;\n\n        cursor: zoom-in !important;\n\n    }\n\n\n\n    .dlw-prod-img:hover {\n\n        transform: scale(1.03) !important;\n\n    }\n\n\n\n    \/* Standard lists (bullets) *\/\n\n    .dlw-list {\n\n        display: flex !important;\n\n        flex-direction: column !important;\n\n        margin-bottom: 2em !important;\n\n        padding-left: 0 !important;\n\n    }\n\n\n\n    .dlw-list-item {\n\n        position: relative !important;\n\n        padding-left: 1.5em !important;\n\n        margin-bottom: 0.8em !important;\n\n        text-align: left !important;\n\n        font-size: 1.25em !important;\n\n        color: #333333 !important;\n\n        display: block !important;\n\n    }\n\n\n\n    .dlw-list-item::before {\n\n        content: \"\u2022\" !important;\n\n        position: absolute !important;\n\n        left: 0 !important;\n\n        color: var(--dlw-blue-cyan) !important;\n\n        font-weight: bold !important;\n\n        font-size: 1.2em !important;\n\n        top: -2px !important;\n\n    }\n\n\n\n    \/* Nested sub-lists *\/\n\n    .dlw-sub-list {\n\n        margin-top: 0.5em !important;\n\n        margin-bottom: 0.5em !important;\n\n        padding-left: 1.5em !important;\n\n    }\n\n\n\n    .dlw-sub-list-item {\n\n        position: relative !important;\n\n        padding-left: 1.2em !important;\n\n        margin-bottom: 0.4em !important;\n\n        font-size: 0.95em !important;\n\n        color: #555555 !important;\n\n        display: block !important;\n\n    }\n\n\n\n    .dlw-sub-list-item::before {\n\n        content: \"-\" !important;\n\n        position: absolute !important;\n\n        left: 0 !important;\n\n        color: var(--dlw-grey) !important;\n\n        font-weight: bold !important;\n\n    }\n\n\n\n    \/* Check lists (Key Features) *\/\n\n    .dlw-check-list {\n\n        display: grid !important;\n\n        grid-template-columns: 1fr 1fr !important;\n\n        gap: 1.5em 2em !important;\n\n        margin: 2em 0 !important;\n\n        background-color: var(--dlw-light-bg) !important;\n\n        padding: 2.5em !important;\n\n        border-radius: 8px !important;\n\n        border-left: 6px solid var(--dlw-blue-cyan) !important;\n\n    }\n\n\n\n    .dlw-check-item {\n\n        display: flex !important;\n\n        align-items: flex-start !important;\n\n        gap: 12px !important;\n\n        font-size: 1.2em !important;\n\n        color: #333333 !important;\n\n        line-height: 1.4 !important;\n\n    }\n\n\n\n    .dlw-check-icon {\n\n        width: 24px !important;\n\n        height: 24px !important;\n\n        min-width: 24px !important;\n\n        fill: var(--dlw-blue-cyan) !important;\n\n        margin-top: 2px !important;\n\n        flex-shrink: 0 !important;\n\n    }\n\n    \n\n    .dlw-check-item:last-child:nth-child(odd) {\n\n        grid-column: 1 \/ -1 !important;\n\n    }\n\n\n\n    \/* Corporate Tables (References) *\/\n\n    .dlw-table {\n\n        width: 100% !important;\n\n        border-collapse: collapse !important;\n\n        margin-bottom: 2.5em !important;\n\n        background-color: #ffffff !important;\n\n        box-shadow: 0 2px 10px rgba(0,0,0,0.03) !important;\n\n        border-radius: 6px !important;\n\n        overflow: hidden !important;\n\n    }\n\n\n\n    .dlw-table th {\n\n        background-color: var(--dlw-blue-dark) !important;\n\n        color: #ffffff !important;\n\n        text-align: left !important;\n\n        padding: 15px 20px !important;\n\n        font-family: 'Raleway', sans-serif !important;\n\n        font-weight: 600 !important;\n\n        text-transform: uppercase !important;\n\n        font-size: 1.1em !important;\n\n        letter-spacing: 0.5px !important;\n\n    }\n\n\n\n    .dlw-table td {\n\n        padding: 15px 20px !important;\n\n        border-bottom: 1px solid var(--dlw-border) !important;\n\n        vertical-align: middle !important;\n\n        font-size: 1.2em !important;\n\n        color: #333333 !important;\n\n    }\n\n    \n\n    .dlw-table tr:hover td {\n\n        background-color: var(--dlw-light-bg) !important;\n\n    }\n\n\n\n    .dlw-table tr:last-child td {\n\n        border-bottom: 2px solid var(--dlw-blue-cyan) !important;\n\n    }\n\n\n\n    .dlw-ref-code {\n\n        font-family: 'Courier New', Courier, monospace !important;\n\n        font-weight: 700 !important;\n\n        color: var(--dlw-blue-dark) !important;\n\n    }\n\n\n\n    \/* Accordions *\/\n\n    .dlw-accordion {\n\n        background-color: #ffffff !important;\n\n        border: 1px solid var(--dlw-border) !important;\n\n        border-radius: 6px !important;\n\n        margin-bottom: 1.5em !important;\n\n        overflow: hidden !important;\n\n        transition: all 0.3s ease !important;\n\n    }\n\n\n\n    .dlw-accordion-header {\n\n        background-color: var(--dlw-blue-dark) !important;\n\n        color: #ffffff !important;\n\n        padding: 15px 20px !important;\n\n        font-family: 'Raleway', sans-serif !important;\n\n        font-weight: 600 !important;\n\n        text-transform: uppercase !important;\n\n        font-size: 1.1em !important;\n\n        letter-spacing: 0.5px !important;\n\n        cursor: pointer !important;\n\n        list-style: none !important;\n\n        position: relative !important;\n\n        display: flex !important;\n\n        justify-content: space-between !important;\n\n        align-items: center !important;\n\n        transition: background-color 0.3s ease !important;\n\n    }\n\n\n\n    \/* Hide default details\/summary arrow *\/\n\n    .dlw-accordion-header::-webkit-details-marker {\n\n        display: none !important;\n\n    }\n\n\n\n    \/* Custom + \/ x icon *\/\n\n    .dlw-accordion-header::after {\n\n        content: '+' !important;\n\n        font-size: 1.8em !important;\n\n        line-height: 1 !important;\n\n        color: var(--dlw-blue-cyan) !important;\n\n        transition: transform 0.3s ease !important;\n\n    }\n\n\n\n    .dlw-accordion[open] .dlw-accordion-header::after {\n\n        transform: rotate(45deg) !important;\n\n    }\n\n\n\n    .dlw-accordion[open] .dlw-accordion-header {\n\n        border-bottom: 2px solid var(--dlw-blue-cyan) !important;\n\n    }\n\n\n\n    \/* Adjustment for lists\/tables inside accordion *\/\n\n    .dlw-accordion-content {\n\n        padding: 20px !important;\n\n        background-color: #ffffff !important;\n\n    }\n\n\n\n    .dlw-accordion-content .dlw-table {\n\n        margin-bottom: 0 !important;\n\n        box-shadow: none !important;\n\n        border-radius: 0 !important;\n\n        border-top: none !important;\n\n    }\n\n\n\n    .dlw-accordion-content .dlw-list {\n\n        margin-bottom: 0 !important;\n\n    }\n\n    \n\n    .dlw-accordion-content p {\n\n        margin-bottom: 0 !important;\n\n    }\n\n\n\n    \/* Modal \/ Lightbox *\/\n\n    .dlw-modal {\n\n        display: none;\n\n        position: fixed !important;\n\n        z-index: 999999 !important;\n\n        left: 0 !important;\n\n        top: 0 !important;\n\n        width: 100vw !important;\n\n        height: 100vh !important;\n\n        background-color: rgba(0, 20, 40, 0.85) !important;\n\n        backdrop-filter: blur(5px) !important;\n\n        align-items: center !important;\n\n        justify-content: center !important;\n\n    }\n\n\n\n    .dlw-modal.dlw-active {\n\n        display: flex !important;\n\n        animation: dlw-fade-in 0.3s ease-out forwards;\n\n    }\n\n\n\n    @keyframes dlw-fade-in {\n\n        from { opacity: 0; }\n\n        to { opacity: 1; }\n\n    }\n\n\n\n    .dlw-modal-img {\n\n        max-width: 90vw !important;\n\n        max-height: 90vh !important;\n\n        width: auto !important;\n\n        height: auto !important;\n\n        border-radius: 6px !important;\n\n        box-shadow: 0 10px 40px rgba(0,0,0,0.5) !important;\n\n        object-fit: contain !important;\n\n    }\n\n\n\n    .dlw-modal-close {\n\n        position: absolute !important;\n\n        top: 25px !important;\n\n        right: 35px !important;\n\n        color: #ffffff !important;\n\n        font-size: 45px !important;\n\n        font-weight: 300 !important;\n\n        cursor: pointer !important;\n\n        transition: color 0.3s ease !important;\n\n        line-height: 1 !important;\n\n        z-index: 9999999 !important;\n\n    }\n\n\n\n    .dlw-modal-close:hover {\n\n        color: var(--dlw-blue-cyan) !important;\n\n    }\n\n\n\n    \/* Responsive *\/\n\n    @media (max-width: 768px) {\n\n        .dlw-lead-box { padding: 1.8em !important; }\n\n        .dlw-check-list { grid-template-columns: 1fr !important; padding: 1.5em !important; }\n\n        .dlw-prod-img { max-width: 100% !important; }\n\n        \n\n        \/* Responsive Tables *\/\n\n        .dlw-table, .dlw-table thead, .dlw-table tbody, .dlw-table th, .dlw-table td, .dlw-table tr { display: block !important; }\n\n        .dlw-table thead tr { position: absolute !important; top: -9999px !important; left: -9999px !important; }\n\n        .dlw-table tr { border-bottom: 2px solid var(--dlw-blue-cyan) !important; margin-bottom: 15px !important; }\n\n        .dlw-table td { border: none !important; position: relative !important; padding-left: 45% !important; }\n\n        .dlw-table td::before { position: absolute !important; top: 15px !important; left: 15px !important; width: 40% !important; white-space: nowrap !important; font-weight: bold !important; color: var(--dlw-blue-dark) !important; font-size: 0.9em !important; text-transform: uppercase !important; }\n\n        .dlw-table td:nth-of-type(1)::before { content: \"Reference\" !important; }\n\n        .dlw-table td:nth-of-type(2)::before { content: \"Description\" !important; }\n\n    }\n\n<\/style>\n\n\n\n<!-- ==========================================\n\n     UNIFIED AND SHIELDED CONTENT\n\n     ========================================== -->\n\n<div class=\"dlw-prod-wrapper\">\n\n\n\n    <!-- Short Description (Lead Box) -->\n\n    <div class=\"dlw-lead-box\">\n\n        <p>In\u2011house targeted enrichment NGS panel for RNA profiling from tissue samples (FFPE). It analyzes 43 genes using a splice\u2011aware probe design anchored to exon boundaries. Detects fusions in a partner-agnostic manner, complex splicing variants, and gene expression profiles in a single workflow.<\/p>\n\n    <\/div>\n\n\n\n    <!-- Detailed Description -->\n\n    <h2>Detailed Description<\/h2>\n\n\n\n    <h3>Principle of operation<\/h3>\n\n    <p>End\u2011to\u2011end solution based on hybrid capture enrichment chemistry for RNA analysis. The assay starts with a specific repair step for RNA derived from FFPE samples. Next, the workflow proceeds through fragmentation, cDNA synthesis (first and second strand), end repair, dA\u2011tailing, and adapter ligation. It stands out for requiring sample inputs of <strong>30 ng<\/strong> of RNA (with <strong>50 ng<\/strong> recommended for tissues with >30% tumor content).<\/p>\n\n    <p>The assay allows simultaneous detection of fusions without prior knowledge of the partner (e.g. ALK, ROS1, RET, NTRK1\/2\/3), characterized splicing variants (e.g. METex14 skipping, EGFR vII\/vIII\/vIVa\/vIVb), and expression levels of selected genes (e.g. CD274, ERBB2).<\/p>\n\n    <p><strong>Analytical Sensitivity:<\/strong><\/p>\n\n    <p>\u2022 <strong>FFPE samples:<\/strong> Detects variants with ><strong>95%<\/strong> sensitivity at 4 copies\/ng levels and ><strong>99%<\/strong> specificity.<\/p>\n\n    <p>\u2022 Shows ><strong>90%<\/strong> concordance against characterized orthogonal assays.<\/p>\n\n\n\n    <!-- Image 1 -->\n\n    <img decoding=\"async\" src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/06\/Imagen-1-1.webp\" alt=\"Hedera Profiling RNA principle of operation\" class=\"dlw-prod-img\" onclick=\"openDlwModal(this.src)\" title=\"\">\n\n\n\n    <p>Library preparation integrates UMI adapters and UDI primers with duplex consensus reading to maximise data reliability, correcting errors and preventing index hopping. After an overnight 16\u2011hour hybridisation, the system delivers sequencing\u2011ready libraries for compatible platforms in just 2 days, allowing multiplexing of up to 8 samples per capture.<\/p>\n\n\n\n    <!-- Image 2 (English) -->\n\n    <img decoding=\"async\" src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/06\/imagen-2-eng.webp\" alt=\"Hedera Profiling RNA workflow\" class=\"dlw-prod-img\" onclick=\"openDlwModal(this.src)\" title=\"\">\n\n\n\n    <p>The analysis is comprehensively completed through <strong>Hedera Prime (CE\u2011IVDR)<\/strong>, a secondary and tertiary analysis software that automates quality control and variant interpretation, presenting results through specific interfaces optimised for each type of genomic alteration.<\/p>\n\n\n\n    <!-- Image 3 (English) -->\n\n    <img decoding=\"async\" src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/06\/Imagen-3-eng-1.webp\" alt=\"Hedera Prime software\" class=\"dlw-prod-img\" onclick=\"openDlwModal(this.src)\" title=\"\">\n\n\n\n    <h3>Clinical applications<\/h3>\n\n    <p>Tool designed exclusively for oncology research environments (RUO) focused on solid tumors. Its multiparametric capability allows laboratories to concurrently evaluate structural and expression evidence, investigating novel or known fusion events, complex splicing alterations, and critical gene expression signatures in the evaluation of tumor biomarkers.<\/p>\n\n\n\n    <h3>Benefits<\/h3>\n\n    <div class=\"dlw-list\">\n\n        <span class=\"dlw-list-item\">Simultaneous analysis of a targeted panel of 43 oncologically relevant genes in a single assay.<\/span>\n\n        <span class=\"dlw-list-item\">Partner-agnostic discovery of relevant oncogenic fusions.<\/span>\n\n        <span class=\"dlw-list-item\">High\u2011resolution detection of alternative splicing through a probe design anchored to exon boundaries.<\/span>\n\n        <span class=\"dlw-list-item\">Low sequencing footprint: requires only 0.25 Gb (~1.6 M reads) per sample, allowing integration into DNA runs without the need for dedicated RNA flow cells.<\/span>\n\n        <span class=\"dlw-list-item\">Consolidated workflow with integrated FFPE repair and minimum inputs of 30 ng of RNA.<\/span>\n\n        <span class=\"dlw-list-item\">Incorporation of UMI technology and UDI primers for read error correction.<\/span>\n\n        <span class=\"dlw-list-item\">Validated compatibility for sequencing runs on Illumina and Element Biosciences AVITI platforms.<\/span>\n\n        <span class=\"dlw-list-item\">Integration of secondary and tertiary bioinformatic analysis through Hedera Prime software with CE\u2011IVDR marking.<\/span>\n\n    <\/div>\n\n\n\n    <h3>Intended user \/ audience<\/h3>\n\n    <div class=\"dlw-list\">\n\n        <span class=\"dlw-list-item\">Laboratories and research groups dedicated to the study, diagnosis, and monitoring of fusions in solid tumors.<\/span>\n\n    <\/div>\n\n\n\n    <!-- Key Features -->\n\n    <h2>Key Features<\/h2>\n\n    \n\n    <div class=\"dlw-check-list\">\n\n        <div class=\"dlw-check-item\">\n\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n\n            <span>Coverage of 43 genes through a splice\u2011aware NGS panel for FFPE tissue RNA with RUO marking.<\/span>\n\n        <\/div>\n\n        <div class=\"dlw-check-item\">\n\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n\n            <span>Simultaneous detection of fusions (partner-agnostic), splicing events (including METex14 skipping and EGFR variant vIII), and gene expression profiling.<\/span>\n\n        <\/div>\n\n        <div class=\"dlw-check-item\">\n\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n\n            <span>Optimized as a high\u2011efficiency sequencing add\u2011on (0.25 Gb per sample).<\/span>\n\n        <\/div>\n\n        <div class=\"dlw-check-item\">\n\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n\n            <span>Hybrid capture enrichment with UMI adapters and duplex consensus UDI primers.<\/span>\n\n        <\/div>\n\n        <div class=\"dlw-check-item\">\n\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n\n            <span>Workflow that allows processing up to 8 samples per capture (24 reactions per kit).<\/span>\n\n        <\/div>\n\n        <div class=\"dlw-check-item\">\n\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n\n            <span>Sample input requirements starting from a minimum of 30 ng of RNA, with a recommendation of 50 ng for tissues with more than 30% tumor content.<\/span>\n\n        <\/div>\n\n        <div class=\"dlw-check-item\">\n\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n\n            <span>Processing capability for sequencing runs on Illumina (NextSeq, NovaSeq) and Element Biosciences AVITI systems.<\/span>\n\n        <\/div>\n\n        <div class=\"dlw-check-item\">\n\n            <svg class=\"dlw-check-icon\" viewBox=\"0 0 24 24\"><path d=\"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2zm-2 15l-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8l-9 9z\"\/><\/svg>\n\n            <span>Automated analysis through the Hedera Prime platform, CE\u2011IVDR marked software that centralises secondary quality control and tertiary variant interpretation.<\/span>\n\n        <\/div>\n\n    <\/div>\n\n\n\n    <!-- Presentation Details (Accordions) -->\n\n    <h2>Presentation Details<\/h2>\n\n\n\n    <details class=\"dlw-accordion\">\n\n        <summary class=\"dlw-accordion-header\">Product identification<\/summary>\n\n        <div class=\"dlw-accordion-content\">\n\n            <div class=\"dlw-list\">\n\n                <span class=\"dlw-list-item\">Commercial name: Hedera Profiling RNA Test Panel.<\/span>\n\n                <span class=\"dlw-list-item\">Product type: Full Solution.<\/span>\n\n                <span class=\"dlw-list-item\">Product family: Assay Enrichment Kit + Hedera Prime Analytics.<\/span>\n\n                <span class=\"dlw-list-item\">Product ID: T40-16SP125IF.<\/span>\n\n                <span class=\"dlw-list-item\">Product version: 1.0.<\/span>\n\n                <span class=\"dlw-list-item\">Sample type: Total RNA (FFPE tissue).<\/span>\n\n            <\/div>\n\n        <\/div>\n\n    <\/details>\n\n\n\n    <details class=\"dlw-accordion\">\n\n        <summary class=\"dlw-accordion-header\">Kit contents<\/summary>\n\n        <div class=\"dlw-accordion-content\">\n\n            <div class=\"dlw-list\">\n\n                <span class=\"dlw-list-item\">Library preparation, Indexing, Purification and isolation.<\/span>\n\n            <\/div>\n\n        <\/div>\n\n    <\/details>\n\n\n\n    <details class=\"dlw-accordion\">\n\n        <summary class=\"dlw-accordion-header\">Required materials (Not included)<\/summary>\n\n        <div class=\"dlw-accordion-content\">\n\n            <div class=\"dlw-list\">\n\n                <span class=\"dlw-list-item\">Quantification and Quality Control (QC): Fluorometric quantification kits and fragment size assessment kits.<\/span>\n\n                <span class=\"dlw-list-item\">Sequencing: Reagents for sequencing runs on Illumina platforms and Illumina PhiX v3 control.<\/span>\n\n            <\/div>\n\n        <\/div>\n\n    <\/details>\n\n\n\n    <!-- Modal Structure (Lightbox) -->\n\n    <div id=\"dlw-image-modal\" class=\"dlw-modal\">\n\n        <span class=\"dlw-modal-close\" onclick=\"closeDlwModal()\">&times;<\/span>\n\n        <img decoding=\"async\" class=\"dlw-modal-img\" id=\"dlw-modal-img-target\" src=\"\" alt=\"\" title=\"\">\n\n    <\/div>\n\n\n\n<\/div>\n\n\n\n<!-- Modal Script (Vanilla JS, no dependencies) -->\n\n<script>\n\n    function openDlwModal(src) {\n\n        var modal = document.getElementById('dlw-image-modal');\n\n        var modalImg = document.getElementById('dlw-modal-img-target');\n\n        modalImg.src = src;\n\n        modal.classList.add('dlw-active');\n\n        document.body.style.overflow = 'hidden'; \/\/ Locks background scroll\n\n    }\n\n\n\n    function closeDlwModal() {\n\n        var modal = document.getElementById('dlw-image-modal');\n\n        modal.classList.remove('dlw-active');\n\n        document.body.style.overflow = 'auto'; \/\/ Restores scroll\n\n    }\n\n\n\n    \/\/ Closes modal if clicking outside the image\n\n    document.getElementById('dlw-image-modal').addEventListener('click', function(e) {\n\n        if (e.target === this) {\n\n            closeDlwModal();\n\n        }\n\n    });\n\n\n\n    \/\/ Closes modal with ESC key\n\n    document.addEventListener('keydown', function(e) {\n\n        if (e.key === \"Escape\" && document.getElementById('dlw-image-modal').classList.contains('dlw-active')) {\n\n            closeDlwModal();\n\n        }\n\n    });\n\n<\/script>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>In\u2011house targeted enrichment NGS panel for RNA profiling from tissue samples (FFPE). It analyzes 43 genes using a splice\u2011aware probe design anchored to exon boundaries. Detects fusions in a partner-agnostic manner, complex splicing variants, and gene expression profiles in a single workflow. Detailed Description Principle of operation End\u2011to\u2011end solution based on hybrid capture enrichment chemistry [&hellip;]<\/p>\n","protected":false},"featured_media":27803,"template":"","tecnologias":[36],"marcas":[249],"familias":[347,460],"class_list":["post-27806","productos","type-productos","status-publish","has-post-thumbnail","hentry","tecnologias-next-generation-sequencing-ngs","marcas-hederadx-en","familias-solid-tumor","familias-fusions"],"_links":{"self":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/27806","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos"}],"about":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/types\/productos"}],"version-history":[{"count":1,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/27806\/revisions"}],"predecessor-version":[{"id":27807,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/27806\/revisions\/27807"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media\/27803"}],"wp:attachment":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media?parent=27806"}],"wp:term":[{"taxonomy":"tecnologias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/tecnologias?post=27806"},{"taxonomy":"marcas","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/marcas?post=27806"},{"taxonomy":"familias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/familias?post=27806"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}