{"id":28206,"date":"2026-08-24T09:35:33","date_gmt":"2026-08-24T09:35:33","guid":{"rendered":"https:\/\/www.dlongwood.com\/?post_type=productos&#038;p=28206"},"modified":"2026-08-24T09:41:20","modified_gmt":"2026-08-24T09:41:20","slug":"homologous-recombination-solutions-hrs","status":"publish","type":"productos","link":"https:\/\/www.dlongwood.com\/en\/product-catalog\/homologous-recombination-solutions-hrs\/","title":{"rendered":"Homologous Recombination Solutions (HRS)"},"content":{"rendered":"\n<!-- Complete HTML ready for WordPress \/ Bricks -->\n<style>\n.dlw-prod-wrapper{\n  --dlw-blue-dark:#003a70;\n  --dlw-blue-cyan:#00a1e0;\n  --dlw-light-bg:#f9fbfd;\n  --dlw-grey-bg:#f4f6f8;\n  --dlw-border:#e1e8f0;\n  --dlw-grey:#939598;\n  width:100%!important;\n  max-width:720px!important;\n  margin:0 auto;\n  color:#24364b;\n  font-family:\"Raleway\",Arial,sans-serif;\n  font-size:16px;\n  line-height:1.7;\n}\n.dlw-prod-wrapper *{box-sizing:border-box}\n.dlw-prod-wrapper h2,\n.dlw-prod-wrapper h3{\n  margin:0 0 18px;\n  font-family:\"Playfair Display\",Georgia,serif;\n  line-height:1.25;\n}\n.dlw-prod-wrapper h2{\n  padding-bottom:10px;\n  border-bottom:2px solid var(--dlw-blue-cyan);\n  color:var(--dlw-blue-dark);\n  font-size:30px;\n}\n.dlw-prod-wrapper h3{\n  color:var(--dlw-blue-cyan);\n  font-size:23px;\n}\n.dlw-prod-wrapper p{\n  margin:0 0 18px;\n  text-align:justify;\n}\n.dlw-section{margin:0 0 46px}\n.dlw-intro{\n  margin-bottom:42px;\n  padding:24px;\n  border-left:5px solid var(--dlw-blue-cyan);\n  background:var(--dlw-light-bg);\n  color:var(--dlw-blue-dark);\n  font-size:18px;\n}\n.dlw-prod-img{\n  display:block;\n  width:auto;\n  max-width:90%!important;\n  height:auto!important;\n  margin:28px auto;\n  border-radius:6px;\n  cursor:zoom-in;\n}\n.dlw-list{\n  display:grid;\n  gap:11px;\n  margin:0 0 22px;\n}\n.dlw-list-item{\n  position:relative;\n  display:block;\n  padding-left:22px;\n}\n.dlw-list-item::before{\n  position:absolute;\n  top:.1em;\n  left:0;\n  color:var(--dlw-blue-cyan);\n  content:\"\u2022\";\n  font-size:22px;\n  font-weight:700;\n}\n.dlw-meta{\n  margin-bottom:28px;\n  padding:20px;\n  border:1px solid var(--dlw-border);\n  border-radius:8px;\n  background:var(--dlw-grey-bg);\n}\n.dlw-meta-row{margin-bottom:10px}\n.dlw-meta-row:last-child{margin-bottom:0}\n.dlw-meta-label{\n  color:var(--dlw-blue-dark);\n  font-weight:700;\n}\n.dlw-table-wrap{\n  width:100%;\n  margin:26px 0 30px;\n}\n.dlw-table{\n  width:100%;\n  table-layout:fixed;\n  border-collapse:collapse;\n  font-size:12.5px;\n  line-height:1.45;\n}\n.dlw-table th,\n.dlw-table td{\n  padding:12px 9px;\n  border:1px solid var(--dlw-border);\n  vertical-align:top;\n  overflow-wrap:anywhere;\n}\n.dlw-table thead th{\n  background:var(--dlw-blue-dark);\n  color:#fff;\n  text-align:left;\n}\n.dlw-table tbody th{\n  width:20%;\n  background:var(--dlw-grey-bg);\n  color:var(--dlw-blue-dark);\n  text-align:left;\n}\n.dlw-cell-list{\n  display:grid;\n  gap:5px;\n}\n.dlw-cell-list span{\n  position:relative;\n  padding-left:12px;\n}\n.dlw-cell-list span::before{\n  position:absolute;\n  left:0;\n  color:var(--dlw-blue-cyan);\n  content:\"\u2022\";\n}\n.dlw-panel-cards{display:none}\n.dlw-panel-card{\n  margin-bottom:20px;\n  overflow:hidden;\n  border:1px solid var(--dlw-border);\n  border-radius:8px;\n  background:#fff;\n}\n.dlw-panel-title{\n  padding:14px 16px;\n  background:var(--dlw-blue-dark);\n  color:#fff;\n  font-weight:700;\n}\n.dlw-panel-field{\n  padding:14px 16px;\n  border-bottom:1px solid var(--dlw-border);\n}\n.dlw-panel-field:last-child{border-bottom:0}\n.dlw-panel-label{\n  display:block;\n  margin-bottom:5px;\n  color:var(--dlw-blue-dark);\n  font-size:13px;\n  font-weight:700;\n  text-transform:uppercase;\n}\n.dlw-modal{\n  position:fixed;\n  z-index:999999;\n  inset:0;\n  display:none;\n  align-items:center;\n  justify-content:center;\n  padding:30px;\n  background:rgba(0,25,48,.92);\n}\n.dlw-modal.dlw-modal-open{display:flex}\n.dlw-modal-image{\n  max-width:95vw;\n  max-height:90vh;\n  object-fit:contain;\n}\n.dlw-modal-close{\n  position:absolute;\n  top:16px;\n  right:20px;\n  padding:4px 12px;\n  border:0;\n  background:transparent;\n  color:#fff;\n  cursor:pointer;\n  font-size:40px;\n  line-height:1;\n}\nbody.dlw-no-scroll{overflow:hidden}\n\n@media (max-width:768px){\n  .dlw-prod-wrapper{\n    width:100%!important;\n    font-size:15px;\n  }\n  .dlw-prod-wrapper h2{font-size:25px}\n  .dlw-prod-wrapper h3{font-size:21px}\n  .dlw-prod-wrapper p{text-align:left}\n  .dlw-intro{padding:19px;font-size:16px}\n  .dlw-prod-img{max-width:100%!important}\n  .dlw-table-wrap{display:none}\n  .dlw-panel-cards{\n    display:block;\n    margin:24px 0 30px;\n  }\n  .dlw-section{margin-bottom:38px}\n  .dlw-modal{padding:15px}\n}\n<\/style>\n\n<div class=\"dlw-prod-wrapper\">\n\n  <!-- EDITORIAL REVIEW: The sequencing platforms assigned to mini HRS and HRS differ between the two tables in the source text. Please verify before publication. The names \u201cExHRS\u201d and \u201cExtHRS\u201d also both appear in the source. -->\n\n  <div class=\"dlw-intro\">\n    Portfolio of hybrid capture-based NGS solutions for the analysis of genes involved in homologous recombination repair (HRR) and the study of alterations associated with the homologous recombination pathway in different types of cancer. The range includes three scalable panels designed to meet different analytical needs: mini HRS, HRS and Extended HRS (ExtHRS).\n  <\/div>\n\n  <section class=\"dlw-section\">\n    <h2>Detailed description<\/h2>\n    <h3>Operating principle<\/h3>\n\n    <p>Comprehensive solution based on hybrid capture technology for the targeted analysis of genes involved in the homologous recombination repair (HRR) pathway.<\/p>\n\n    <img decoding=\"async\"\n      src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/08\/1-eng-2.webp\"\n      alt=\"Operating principle of the SOPHiA DDM HRS solutions\"\n      class=\"dlw-prod-img\"\n      loading=\"lazy\"\n      onclick=\"openDlwModal(this.src,this.alt)\"\n    >\n\n    <p>The assay provides an efficient workflow starting with a recommended input of 50 ng of DNA extracted from formalin-fixed, paraffin-embedded (FFPE) tumour tissue or fresh-frozen tissue. Library preparation produces sequencing-ready libraries in just 1.5 days, with an automation option and minimal hands-on time.<\/p>\n\n    <p>The portfolio can be flexibly scaled across three capture-panel configurations according to the laboratory\u2019s objectives:<\/p>\n\n    <div class=\"dlw-table-wrap\">\n      <table class=\"dlw-table\">\n        <thead>\n          <tr>\n            <th scope=\"col\">Feature<\/th>\n            <th scope=\"col\">mini HRS<\/th>\n            <th scope=\"col\">HRS<\/th>\n            <th scope=\"col\">Extended HRS (ExtHRS)<\/th>\n          <\/tr>\n        <\/thead>\n        <tbody>\n          <tr>\n            <th scope=\"row\">Genes included<\/th>\n            <td><strong>4 genes<\/strong><br>BRCA1, BRCA2, RAD51C, TP53<\/td>\n            <td><strong>16 genes<\/strong><br>ATM, BARD1, BRCA1, BRCA2, BRIP1, CDK12, CHEK1, CHEK2, FANCL, PALB2, PPP2R2A, RAD51B, RAD51C, RAD51D, RAD54L, TP53<\/td>\n            <td><strong>28 genes<\/strong><br>AKT1*, ATM, BARD1, BRCA1, BRCA2, BRIP1, CCNE1, CDK12, CHEK1, CHEK2, ESR1*, FANCA, FANCD2, FANCL, FGFR1*, FGFR2*, FGFR3*, MRE11, NBN, PALB2, PIK3CA*, PPP2R2A, PTEN, RAD51B, RAD51C, RAD51D, RAD54L, TP53<\/td>\n          <\/tr>\n          <tr>\n            <th scope=\"row\">Sample type<\/th>\n            <td>FFPE, fresh-frozen tissue<\/td>\n            <td>FFPE, fresh-frozen tissue<\/td>\n            <td>FFPE, fresh-frozen tissue<\/td>\n          <\/tr>\n          <tr>\n            <th scope=\"row\">DNA input<\/th>\n            <td>50 ng recommended<\/td>\n            <td>50 ng recommended<\/td>\n            <td>50 ng recommended<\/td>\n          <\/tr>\n          <tr>\n            <th scope=\"row\">Reads per sample (2\u00d7150 bp)<\/th>\n            <td>1.6 million<\/td>\n            <td>4.7 million<\/td>\n            <td>8 million<\/td>\n          <\/tr>\n          <tr>\n            <th scope=\"row\">Compatible sequencing platforms<\/th>\n            <td>\n              <div class=\"dlw-cell-list\">\n                <span>Illumina MiSeq\u00ae (v3)<\/span>\n                <span>Illumina MiSeq\u00ae (v2)<\/span>\n                <span>Ion Torrent&#x2122; Ion S5&#x2122; System<\/span>\n              <\/div>\n            <\/td>\n            <td>\n              <div class=\"dlw-cell-list\">\n                <span>Illumina MiniSeq&#x2122;<\/span>\n                <span>Illumina MiSeq\u00ae (v3)<\/span>\n                <span>Illumina MiSeq\u00ae (v2)<\/span>\n              <\/div>\n            <\/td>\n            <td>Illumina\u00ae NextSeq\u00ae 500\/550<sup>a<\/sup><br>Also compatible with NovaSeq\u00ae sequencers<\/td>\n          <\/tr>\n        <\/tbody>\n      <\/table>\n    <\/div>\n\n    <div class=\"dlw-panel-cards\">\n      <div class=\"dlw-panel-card\">\n        <div class=\"dlw-panel-title\">mini HRS<\/div>\n        <div class=\"dlw-panel-field\">\n          <span class=\"dlw-panel-label\">Genes included<\/span>\n          <strong>4 genes:<\/strong> BRCA1, BRCA2, RAD51C, TP53\n        <\/div>\n        <div class=\"dlw-panel-field\">\n          <span class=\"dlw-panel-label\">Sample type<\/span>\n          FFPE, fresh-frozen tissue\n        <\/div>\n        <div class=\"dlw-panel-field\">\n          <span class=\"dlw-panel-label\">DNA input<\/span>\n          50 ng recommended\n        <\/div>\n        <div class=\"dlw-panel-field\">\n          <span class=\"dlw-panel-label\">Reads per sample<\/span>\n          1.6 million (2\u00d7150 bp)\n        <\/div>\n        <div class=\"dlw-panel-field\">\n          <span class=\"dlw-panel-label\">Compatible platforms<\/span>\n          <div class=\"dlw-cell-list\">\n            <span>Illumina MiSeq\u00ae (v3)<\/span>\n            <span>Illumina MiSeq\u00ae (v2)<\/span>\n            <span>Ion Torrent&#x2122; Ion S5&#x2122; System<\/span>\n          <\/div>\n        <\/div>\n      <\/div>\n\n      <div class=\"dlw-panel-card\">\n        <div class=\"dlw-panel-title\">HRS<\/div>\n        <div class=\"dlw-panel-field\">\n          <span class=\"dlw-panel-label\">Genes included<\/span>\n          <strong>16 genes:<\/strong> ATM, BARD1, BRCA1, BRCA2, BRIP1, CDK12, CHEK1, CHEK2, FANCL, PALB2, PPP2R2A, RAD51B, RAD51C, RAD51D, RAD54L, TP53\n        <\/div>\n        <div class=\"dlw-panel-field\">\n          <span class=\"dlw-panel-label\">Sample type<\/span>\n          FFPE, fresh-frozen tissue\n        <\/div>\n        <div class=\"dlw-panel-field\">\n          <span class=\"dlw-panel-label\">DNA input<\/span>\n          50 ng recommended\n        <\/div>\n        <div class=\"dlw-panel-field\">\n          <span class=\"dlw-panel-label\">Reads per sample<\/span>\n          4.7 million (2\u00d7150 bp)\n        <\/div>\n        <div class=\"dlw-panel-field\">\n          <span class=\"dlw-panel-label\">Compatible platforms<\/span>\n          <div class=\"dlw-cell-list\">\n            <span>Illumina MiniSeq&#x2122;<\/span>\n            <span>Illumina MiSeq\u00ae (v3)<\/span>\n            <span>Illumina MiSeq\u00ae (v2)<\/span>\n          <\/div>\n        <\/div>\n      <\/div>\n\n      <div class=\"dlw-panel-card\">\n        <div class=\"dlw-panel-title\">Extended HRS (ExtHRS)<\/div>\n        <div class=\"dlw-panel-field\">\n          <span class=\"dlw-panel-label\">Genes included<\/span>\n          <strong>28 genes:<\/strong> AKT1*, ATM, BARD1, BRCA1, BRCA2, BRIP1, CCNE1, CDK12, CHEK1, CHEK2, ESR1*, FANCA, FANCD2, FANCL, FGFR1*, FGFR2*, FGFR3*, MRE11, NBN, PALB2, PIK3CA*, PPP2R2A, PTEN, RAD51B, RAD51C, RAD51D, RAD54L, TP53\n        <\/div>\n        <div class=\"dlw-panel-field\">\n          <span class=\"dlw-panel-label\">Sample type<\/span>\n          FFPE, fresh-frozen tissue\n        <\/div>\n        <div class=\"dlw-panel-field\">\n          <span class=\"dlw-panel-label\">DNA input<\/span>\n          50 ng recommended\n        <\/div>\n        <div class=\"dlw-panel-field\">\n          <span class=\"dlw-panel-label\">Reads per sample<\/span>\n          8 million (2\u00d7150 bp)\n        <\/div>\n        <div class=\"dlw-panel-field\">\n          <span class=\"dlw-panel-label\">Compatible platforms<\/span>\n          Illumina\u00ae NextSeq\u00ae 500\/550<sup>a<\/sup>. Also compatible with NovaSeq\u00ae sequencers.\n        <\/div>\n      <\/div>\n    <\/div>\n\n    <img decoding=\"async\"\n      src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/08\/2-eng.webp\"\n      alt=\"Comparison of the mini HRS, HRS and Extended HRS panels\"\n      class=\"dlw-prod-img\"\n      loading=\"lazy\"\n      onclick=\"openDlwModal(this.src,this.alt)\"\n    >\n  <\/section>\n\n  <section class=\"dlw-section\">\n    <h2>HRD analysis and how GIInger&#x2122; works<\/h2>\n\n    <p>Although all three panels can identify point mutations and indels in HRR pathway genes, <strong>only the Extended HRS (ExtHRS) solution can assess overall Homologous Recombination Deficiency (HRD) status<\/strong>. This assessment requires the complementary use of <strong>GIInger&#x2122;<\/strong>, an advanced algorithm based on deep learning.<\/p>\n\n    <p>GIInger&#x2122; has been specifically trained to recognise genomic signatures and \u201cscars\u201d characteristic of DNA damage (<em>genomic scars<\/em>).<\/p>\n\n    <p>The algorithm analyses genomic instability (GI) profiles obtained through low-coverage whole-genome sequencing (lpWGS, <em>low-pass Whole Genome Sequencing<\/em>).<\/p>\n\n    <p>Based on these large-scale structural instability patterns, the system objectively calculates genomic integrity status and classifies the sample as <strong>HRD-positive<\/strong> or <strong>HRD-negative<\/strong>. This provides key predictive information that goes beyond the isolated detection of variants in susceptibility genes.<\/p>\n\n    <img decoding=\"async\"\n      src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/08\/3-eng-1.webp\"\n      alt=\"HRD analysis using GIInger and low-pass whole-genome sequencing\"\n      class=\"dlw-prod-img\"\n      loading=\"lazy\"\n      onclick=\"openDlwModal(this.src,this.alt)\"\n    >\n  <\/section>\n\n  <section class=\"dlw-section\">\n    <h2>Clinical applications<\/h2>\n\n    <p>This tool is intended for research into the mutational profile of the homologous recombination repair (HRR) pathway in FFPE or fresh-frozen tissue samples. Its applications include in-depth molecular characterisation of several types of cancer, such as ovarian, breast, prostate, colorectal, lung and pancreatic cancer.<\/p>\n\n    <img decoding=\"async\"\n      src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/08\/imagen-4.webp\"\n      alt=\"Applications of HRS panels across different cancer types\"\n      class=\"dlw-prod-img\"\n      loading=\"lazy\"\n      onclick=\"openDlwModal(this.src,this.alt)\"\n    >\n  <\/section>\n\n  <section class=\"dlw-section\">\n    <h2>Benefits<\/h2>\n\n    <div class=\"dlw-list\">\n      <span class=\"dlw-list-item\">Scalable portfolio comprising three gene panels.<\/span>\n      <span class=\"dlw-list-item\">Complete coverage of the coding regions and splice junctions of the included genes.<\/span>\n      <span class=\"dlw-list-item\">Optimised probe design to maximise coverage and uniformity.<\/span>\n      <span class=\"dlw-list-item\">Library preparation in approximately 1.5 days.<\/span>\n      <span class=\"dlw-list-item\">Integrated sample-to-report solution.<\/span>\n      <span class=\"dlw-list-item\">Compatibility with multiple Illumina\u00ae platforms.<\/span>\n      <span class=\"dlw-list-item\">Automation available to support implementation.<\/span>\n      <span class=\"dlw-list-item\">Advanced interpretation and report-generation tools.<\/span>\n      <span class=\"dlw-list-item\">Access to the SOPHiA GENETICS community for support with variant interpretation.<\/span>\n    <\/div>\n  <\/section>\n\n  <section class=\"dlw-section\">\n    <h2>Technology<\/h2>\n\n    <p>SOPHiA DDM&#x2122; HRS solutions use targeted hybrid capture technology and next-generation sequencing (NGS) to analyse genes involved in the homologous recombination repair (HRR) pathway. The assays incorporate SOPHiA GENETICS&#x2122; Universal Library Prep for library preparation and specific capture probes to enrich the coding regions and splice sites of the genes included in each panel. Bioinformatic analysis is performed using the SOPHiA DDM&#x2122; platform, enabling the detection of SNVs, indels and gene amplifications, as well as automated interpretation of the identified alterations.<\/p>\n  <\/section>\n\n  <section class=\"dlw-section\">\n    <h2>Intended users<\/h2>\n\n    <div class=\"dlw-list\">\n      <span class=\"dlw-list-item\">Molecular genetics laboratories.<\/span>\n      <span class=\"dlw-list-item\">Molecular oncology laboratories.<\/span>\n      <span class=\"dlw-list-item\">Oncology research centres.<\/span>\n      <span class=\"dlw-list-item\">Institutions conducting HRR\/HRD biomarker studies using NGS.<\/span>\n    <\/div>\n  <\/section>\n\n  <section class=\"dlw-section\">\n    <h2>Additional considerations<\/h2>\n\n    <div class=\"dlw-list\">\n      <span class=\"dlw-list-item\">For Research Use Only (RUO).<\/span>\n      <span class=\"dlw-list-item\">Not intended for diagnostic procedures.<\/span>\n      <span class=\"dlw-list-item\">Performance may vary depending on the sequencing platform used.<\/span>\n      <span class=\"dlw-list-item\">Analysis time depends on the number of samples processed and the system workload.<\/span>\n    <\/div>\n  <\/section>\n\n  <section class=\"dlw-section\">\n    <h2>Key features<\/h2>\n\n    <div class=\"dlw-list\">\n      <span class=\"dlw-list-item\">Portfolio comprising three panels: mini HRS, HRS and ExtHRS.<\/span>\n      <span class=\"dlw-list-item\">Analysis of genes involved in homologous recombination repair (HRR).<\/span>\n      <span class=\"dlw-list-item\">Complete coverage of coding regions and relevant splice regions.<\/span>\n      <span class=\"dlw-list-item\">Detection of SNVs, indels and gene amplifications.<\/span>\n      <span class=\"dlw-list-item\">Integrated workflow from library preparation to final report.<\/span>\n      <span class=\"dlw-list-item\">SOPHiA DDM&#x2122; platform for analysis and interpretation.<\/span>\n      <span class=\"dlw-list-item\">Compatible with multiple Illumina\u00ae platforms.<\/span>\n      <span class=\"dlw-list-item\">Library preparation in approximately 1.5 days.<\/span>\n      <span class=\"dlw-list-item\">Access to advanced interpretation and report-generation tools.<\/span>\n    <\/div>\n  <\/section>\n\n  <section class=\"dlw-section\">\n    <h2>Product details<\/h2>\n\n    <div class=\"dlw-meta\">\n      <div class=\"dlw-meta-row\">\n        <span class=\"dlw-meta-label\">Product type:<\/span>\n        Bundle solution (wet-lab reagents + analytical credits for the cloud-based SOPHiA DDM&#x2122; platform).\n      <\/div>\n      <div class=\"dlw-meta-row\">\n        <span class=\"dlw-meta-label\">Sample type:<\/span>\n        FFPE.\n      <\/div>\n    <\/div>\n\n    <div class=\"dlw-table-wrap\">\n      <table class=\"dlw-table\">\n        <thead>\n          <tr>\n            <th scope=\"col\">Feature<\/th>\n            <th scope=\"col\">SOPHiA DDM&#x2122; mini HRS<\/th>\n            <th scope=\"col\">SOPHiA DDM&#x2122; HRS<\/th>\n            <th scope=\"col\">SOPHiA DDM&#x2122; ExHRS<\/th>\n          <\/tr>\n        <\/thead>\n        <tbody>\n          <tr>\n            <th scope=\"row\">Samples<\/th>\n            <td>\n              <div class=\"dlw-cell-list\">\n                <span>Up to 24 samples for Illumina MiniSeq&#x2122; kit<\/span>\n                <span>Up to 32 samples for Illumina MiSeq\u00ae kit v3<\/span>\n                <span>Up to 24 samples for Illumina MiSeq\u00ae kit v2<\/span>\n              <\/div>\n            <\/td>\n            <td>\n              <div class=\"dlw-cell-list\">\n                <span>Up to 8 samples for Illumina MiSeq\u00ae kit v3<\/span>\n                <span>Up to 4 samples for Illumina MiSeq\u00ae kit v2<\/span>\n                <span>Up to 16 samples for Ion Torrent&#x2122; Ion S5&#x2122; System<\/span>\n              <\/div>\n            <\/td>\n            <td>Up to 32 samples for Illumina\u00ae NextSeq\u00ae 500\/550 Mid Output Kit<sup>a<\/sup><\/td>\n          <\/tr>\n          <tr>\n            <th scope=\"row\">Product codes<\/th>\n            <td>\n              BS0111ILLRSMY05-16;<br>\n              BS0111ILLRSMY05-32;<br>\n              BS0111ILLRSMY05-48\n            <\/td>\n            <td>\n              <strong>MiSeq\u00ae:<\/strong><br>\n              BS0108ILLRSMY05-16;<br>\n              BS0108ILLRSMY05-32;<br>\n              BS0108ILLRSMY05-48<br><br>\n              <strong>IonTorrent&#x2122;:<\/strong><br>\n              BS0108TFSRSML03-016;<br>\n              BS0108TFSRSML03-032\n            <\/td>\n            <td>\n              BS0128ILLRSMY10-16;<br>\n              BS0128ILLRSMY10-32;<br>\n              BS0128ILLRSMY10-48;<br>\n              BS0128ILLRSMY10-96\n            <\/td>\n          <\/tr>\n        <\/tbody>\n      <\/table>\n    <\/div>\n\n    <div class=\"dlw-panel-cards\">\n      <div class=\"dlw-panel-card\">\n        <div class=\"dlw-panel-title\">SOPHiA DDM&#x2122; mini HRS<\/div>\n        <div class=\"dlw-panel-field\">\n          <span class=\"dlw-panel-label\">Samples<\/span>\n          <div class=\"dlw-cell-list\">\n            <span>Up to 24 samples for Illumina MiniSeq&#x2122; kit<\/span>\n            <span>Up to 32 samples for Illumina MiSeq\u00ae kit v3<\/span>\n            <span>Up to 24 samples for Illumina MiSeq\u00ae kit v2<\/span>\n          <\/div>\n        <\/div>\n        <div class=\"dlw-panel-field\">\n          <span class=\"dlw-panel-label\">Product codes<\/span>\n          BS0111ILLRSMY05-16;<br>\n          BS0111ILLRSMY05-32;<br>\n          BS0111ILLRSMY05-48\n        <\/div>\n      <\/div>\n\n      <div class=\"dlw-panel-card\">\n        <div class=\"dlw-panel-title\">SOPHiA DDM&#x2122; HRS<\/div>\n        <div class=\"dlw-panel-field\">\n          <span class=\"dlw-panel-label\">Samples<\/span>\n          <div class=\"dlw-cell-list\">\n            <span>Up to 8 samples for Illumina MiSeq\u00ae kit v3<\/span>\n            <span>Up to 4 samples for Illumina MiSeq\u00ae kit v2<\/span>\n            <span>Up to 16 samples for Ion Torrent&#x2122; Ion S5&#x2122; System<\/span>\n          <\/div>\n        <\/div>\n        <div class=\"dlw-panel-field\">\n          <span class=\"dlw-panel-label\">Product codes<\/span>\n          <strong>MiSeq\u00ae:<\/strong><br>\n          BS0108ILLRSMY05-16;<br>\n          BS0108ILLRSMY05-32;<br>\n          BS0108ILLRSMY05-48<br><br>\n          <strong>IonTorrent&#x2122;:<\/strong><br>\n          BS0108TFSRSML03-016;<br>\n          BS0108TFSRSML03-032\n        <\/div>\n      <\/div>\n\n      <div class=\"dlw-panel-card\">\n        <div class=\"dlw-panel-title\">SOPHiA DDM&#x2122; ExHRS<\/div>\n        <div class=\"dlw-panel-field\">\n          <span class=\"dlw-panel-label\">Samples<\/span>\n          Up to 32 samples for Illumina\u00ae NextSeq\u00ae 500\/550 Mid Output Kit<sup>a<\/sup>\n        <\/div>\n        <div class=\"dlw-panel-field\">\n          <span class=\"dlw-panel-label\">Product codes<\/span>\n          BS0128ILLRSMY10-16;<br>\n          BS0128ILLRSMY10-32;<br>\n          BS0128ILLRSMY10-48;<br>\n          BS0128ILLRSMY10-96\n        <\/div>\n      <\/div>\n    <\/div>\n\n    <h3>What does the solution include?<\/h3>\n\n    <div class=\"dlw-list\">\n      <span class=\"dlw-list-item\">SOPHiA GENETICS Universal Library Prep reagents for library preparation from fragmented DNA.<\/span>\n      <span class=\"dlw-list-item\">Hybridisation probes for targeted capture.<\/span>\n      <span class=\"dlw-list-item\">Full access and credits for secondary and tertiary analysis on the SOPHiA DDM&#x2122; platform.<\/span>\n    <\/div>\n\n    <h3>Required reagents and materials not included in the kit<\/h3>\n\n    <div class=\"dlw-list\">\n      <span class=\"dlw-list-item\">Genomic DNA extraction kits for FFPE samples.<\/span>\n      <span class=\"dlw-list-item\">Equipment and reagents for fluorometric quantification and nucleic acid quality control, such as Qubit&#x2122;, TapeStation&#x2122; or equivalent.<\/span>\n      <span class=\"dlw-list-item\">Sequencing reagents specific to Illumina platforms and Illumina PhiX v3 control.<\/span>\n    <\/div>\n  <\/section>\n\n  <div class=\"dlw-modal\" role=\"dialog\" aria-modal=\"true\" aria-label=\"Enlarged image\">\n    <button class=\"dlw-modal-close\" type=\"button\" aria-label=\"Close image\">&times;<\/button>\n    <img decoding=\"async\" class=\"dlw-modal-image\" src=\"\" alt=\"\" title=\"\">\n  <\/div>\n<\/div>\n\n<script>\n(function () {\n  var modal;\n  var modalImage;\n  var closeButton;\n\n  window.openDlwModal = function (src, alt) {\n    modal = document.querySelector('.dlw-prod-wrapper .dlw-modal');\n    modalImage = modal.querySelector('.dlw-modal-image');\n    closeButton = modal.querySelector('.dlw-modal-close');\n\n    modalImage.src = src;\n    modalImage.alt = alt || '';\n    modal.classList.add('dlw-modal-open');\n    document.body.classList.add('dlw-no-scroll');\n    closeButton.focus();\n  };\n\n  function closeDlwModal() {\n    if (!modal) {\n      modal = document.querySelector('.dlw-prod-wrapper .dlw-modal');\n    }\n\n    if (!modal) return;\n\n    modalImage = modal.querySelector('.dlw-modal-image');\n    modal.classList.remove('dlw-modal-open');\n    modalImage.src = '';\n    modalImage.alt = '';\n    document.body.classList.remove('dlw-no-scroll');\n  }\n\n  document.addEventListener('click', function (event) {\n    if (event.target.matches('.dlw-modal-close')) {\n      closeDlwModal();\n    }\n\n    if (event.target.matches('.dlw-modal')) {\n      closeDlwModal();\n    }\n  });\n\n  document.addEventListener('keydown', function (event) {\n    if (event.key === 'Escape') {\n      closeDlwModal();\n    }\n  });\n})();\n<\/script>\n","protected":false},"excerpt":{"rendered":"<p>Portfolio of hybrid capture-based NGS solutions for the analysis of genes involved in homologous recombination repair (HRR) and the study of alterations associated with the homologous recombination pathway in different types of cancer. The range includes three scalable panels designed to meet different analytical needs: mini HRS, HRS and Extended HRS (ExtHRS). Detailed description Operating [&hellip;]<\/p>\n","protected":false},"featured_media":28196,"template":"","tecnologias":[36],"marcas":[215],"familias":[347,465,466,461,468,469],"class_list":["post-28206","productos","type-productos","status-publish","has-post-thumbnail","hentry","tecnologias-next-generation-sequencing-ngs","marcas-sophia-genetics-en","familias-solid-tumor","familias-digestive-system","familias-endocrine-system","familias-hrd-en","familias-reproductive-system","familias-respiratory-system"],"_links":{"self":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/28206","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos"}],"about":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/types\/productos"}],"version-history":[{"count":1,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/28206\/revisions"}],"predecessor-version":[{"id":28207,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/28206\/revisions\/28207"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media\/28196"}],"wp:attachment":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media?parent=28206"}],"wp:term":[{"taxonomy":"tecnologias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/tecnologias?post=28206"},{"taxonomy":"marcas","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/marcas?post=28206"},{"taxonomy":"familias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/familias?post=28206"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}