{"id":28311,"date":"2026-09-01T06:39:29","date_gmt":"2026-09-01T06:39:29","guid":{"rendered":"https:\/\/www.dlongwood.com\/?post_type=productos&#038;p=28311"},"modified":"2026-09-01T06:43:31","modified_gmt":"2026-09-01T06:43:31","slug":"seqone-genomics-somatic","status":"publish","type":"productos","link":"https:\/\/www.dlongwood.com\/en\/product-catalog\/seqone-genomics-somatic\/","title":{"rendered":"SeqOne Genomics \u2013 Somatic"},"content":{"rendered":"\n<!-- Complete English HTML ready for WordPress \/ Bricks -->\n\n<style>\n.dlw-prod-wrapper {\n    --dlw-blue-dark: #003a70;\n    --dlw-blue-cyan: #00a1e0;\n    --dlw-light-bg: #f9fbfd;\n    --dlw-border: #e1e8f0;\n\n    width: 100% !important;\n    max-width: 720px !important;\n    margin: 0 auto !important;\n    padding: 24px !important;\n    box-sizing: border-box !important;\n    overflow-wrap: anywhere;\n    color: #263746;\n    background: #fff;\n    font-family: \"Raleway\", Arial, sans-serif;\n    font-size: 16px;\n    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font-size: 42px;\n    line-height: 1;\n}\n\n@media (max-width: 768px) {\n    .dlw-prod-wrapper {\n        width: 100% !important;\n        max-width: 100% !important;\n        padding: 18px 14px !important;\n    }\n\n    .dlw-prod-wrapper h2 {\n        font-size: 25px !important;\n    }\n\n    .dlw-prod-wrapper h3 {\n        font-size: 21px !important;\n    }\n\n    .dlw-prod-wrapper p {\n        text-align: left;\n    }\n\n    .dlw-prod-intro,\n    .dlw-module {\n        padding: 16px;\n    }\n\n    .dlw-prod-img {\n        max-width: 100% !important;\n    }\n\n    .dlw-modal {\n        padding: 16px;\n    }\n\n    .dlw-modal-close {\n        top: 5px;\n        right: 8px;\n    }\n}\n<\/style>\n\n<div class=\"dlw-prod-wrapper\">\n    <div class=\"dlw-prod-img-wrap\">\n        <img decoding=\"async\"\n            src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/09\/1.webp\"\n            alt=\"SeqOne bioinformatics platform for NGS data analysis\"\n            class=\"dlw-prod-img\"\n            onclick=\"openDlwModal(this.src, this.alt)\"\n        >\n    <\/div>\n\n    <p class=\"dlw-prod-intro\">\n        <strong>SeqOne<\/strong> is a bioinformatics platform for NGS data analysis in precision oncology, designed to detect, prioritise and interpret somatic variants and generate actionable clinical reports from raw sequencing data. It helps laboratories and healthcare professionals accelerate the interpretation of NGS data through an end-to-end workflow.\n    <\/p>\n\n    <h2>Detailed description<\/h2>\n\n    <h3>Operating principle<\/h3>\n\n    <p>\n        SeqOne Genomics is a genomic data analysis and interpretation platform that covers the entire workflow, from raw NGS data to the generation of clinically actionable information. It integrates advanced bioinformatics algorithms and machine-learning models to detect, prioritise and classify somatic genetic variants. It also includes filtering tools, annotation using premium clinical databases and the automated generation of interpretative reports.\n    <\/p>\n\n    <p>\n        The platform provides an end-to-end solution that includes data transfer, quality control, alignment, variant calling, variant classification, complete report generation and LIMS integration.\n    <\/p>\n\n    <div class=\"dlw-prod-img-wrap\">\n        <img decoding=\"async\"\n            src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/09\/Imagen2.webp\"\n            alt=\"SeqOne platform end-to-end workflow\"\n            class=\"dlw-prod-img\"\n            onclick=\"openDlwModal(this.src, this.alt)\"\n        >\n    <\/div>\n\n    <h3>Clinical applications<\/h3>\n\n    <p>\n        The software is intended for somatic analysis in oncology, including solid tumours, haematological malignancies and liquid biopsy. In oncology, it provides variant interpretation, treatment recommendations and information about geolocated clinical trials.\n    <\/p>\n\n    <p>The oncology application suite includes the following modules:<\/p>\n\n    <div class=\"dlw-module\">\n        <p>\n            <strong>SOMAVAR:<\/strong> an application for the advanced bioinformatics analysis of somatic DNA panels. It enables sensitive detection of somatic variants and fusions in targeted gene panels\u2014whether capture- or amplicon-based\u2014with SNV and indel detection at a sensitivity of up to 1% VAF, as well as filtering, prioritisation and classification tools.\n        <\/p>\n    <\/div>\n\n    <div class=\"dlw-module\">\n        <p>\n            <strong>SOMAHEMATO:<\/strong> an application specifically designed to detect and interpret key haematological markers, including FLT3-ITD, KMT2A-PTD, IARC annotation of TP53 and fusions. It includes a dedicated module for the reliable determination of IGHV mutational status in chronic lymphocytic leukaemia (CLL).\n        <\/p>\n    <\/div>\n\n    <div class=\"dlw-prod-img-wrap\">\n        <img decoding=\"async\"\n            src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/09\/3.webp\"\n            alt=\"SeqOne SOMALBX and SOMARNA applications\"\n            class=\"dlw-prod-img\"\n            onclick=\"openDlwModal(this.src, this.alt)\"\n        >\n    <\/div>\n\n    <div class=\"dlw-module\">\n        <p>\n            <strong>SOMALBX:<\/strong> a specialised liquid-biopsy (ctDNA) solution designed to maximise the detection of somatic variants in tumour samples without requiring a matched normal sample\u2014a tumour-only workflow. It enables the identification of SNVs, indels, CNVs and fusions or translocations with high sensitivity, down to a VAF of 0.1%. It is intended for early cancer detection, treatment-response monitoring and recurrence surveillance.\n        <\/p>\n    <\/div>\n\n    <div class=\"dlw-module\">\n        <p>\n            <strong>SOMARNA:<\/strong> a solution for identifying and visualising fusions from RNA-seq data.\n        <\/p>\n    <\/div>\n\n    <div class=\"dlw-prod-img-wrap\">\n        <img decoding=\"async\"\n            src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/09\/4.webp\"\n            alt=\"SeqOne SOMACNV CAPTURE application\"\n            class=\"dlw-prod-img\"\n            onclick=\"openDlwModal(this.src, this.alt)\"\n        >\n    <\/div>\n\n    <div class=\"dlw-module\">\n        <p>\n            <strong>SOMACNV CAPTURE:<\/strong> designed to detect somatic CNVs (\u2265300 bp) from capture-panel NGS data. This analysis is always performed after a preliminary analysis in another mode, such as SOMAVAR or SOMAHEMATO.\n        <\/p>\n    <\/div>\n\n    <div class=\"dlw-prod-img-wrap\">\n        <img decoding=\"async\"\n            src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/09\/5.webp\"\n            alt=\"Somatic variant analysis using SeqOne\"\n            class=\"dlw-prod-img\"\n            onclick=\"openDlwModal(this.src, this.alt)\"\n        >\n    <\/div>\n\n    <div class=\"dlw-module\">\n        <p>\n            <strong>Deepmode function:<\/strong> enables dynamic control of the VAF threshold in SOMAVAR and SOMAHEMATO, with manual adjustment between 0.01% and 1%.\n        <\/p>\n    <\/div>\n\n    <div class=\"dlw-prod-img-wrap\">\n        <img decoding=\"async\"\n            src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/09\/6.webp\"\n            alt=\"SOMAHRD solution for determining HRD status\"\n            class=\"dlw-prod-img\"\n            onclick=\"openDlwModal(this.src, this.alt)\"\n        >\n    <\/div>\n\n    <div class=\"dlw-module\">\n        <p>\n            <strong>SOMAHRD:<\/strong> a solution for determining HRD status in solid tumours, validated using data from the PAOLA-1 trial. It combines a gene panel (BRCA1\/2) with low-coverage whole-genome sequencing (sWGS) to measure genomic instability (LGA and LPC) and detect amplifications in CCNE1 and RAD51B.\n        <\/p>\n    <\/div>\n\n    <div class=\"dlw-prod-img-wrap\">\n        <img decoding=\"async\"\n            src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/09\/7.webp\"\n            alt=\"Genomic analysis results generated using SeqOne\"\n            class=\"dlw-prod-img\"\n            onclick=\"openDlwModal(this.src, this.alt)\"\n        >\n    <\/div>\n\n    <h2>Benefits<\/h2>\n\n    <p>\n        The platform provides a flexible solution for molecular laboratories that need to interpret complex NGS data within clinically relevant time frames. It delivers robust interpretations through regularly updated databases and automated classification.\n    <\/p>\n\n    <p>\n        It offers the flexibility to adapt panels and workflows to changing clinical requirements, as the tool is compatible with numerous sequencers\u2014including Illumina, MGI and Oxford Nanopore\u2014and reagent kits.\n    <\/p>\n\n    <h2>Technology<\/h2>\n\n    <p>\n        SeqOne Genomics is cloud-based software that uses artificial intelligence and machine learning to prioritise variants. It integrates annotation databases such as OMIM, COSMIC, CIViC, MolecularMatch and others, together with international guidelines for biological and clinical interpretation, including ACMG, AMP\/ASCO and ComPerMed. The platform incorporates regular updates to biological, clinical and therapeutic databases.\n    <\/p>\n\n    <div class=\"dlw-prod-img-wrap\">\n        <img decoding=\"async\"\n            src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/09\/8.webp\"\n            alt=\"Technology and databases integrated into the SeqOne platform\"\n            class=\"dlw-prod-img\"\n            onclick=\"openDlwModal(this.src, this.alt)\"\n        >\n    <\/div>\n\n    <h2>Intended users<\/h2>\n\n    <p>\n        The product is intended for molecular laboratories performing NGS analyses, as well as biologists, pathologists, clinicians and oncologists. It is also intended for biotechnology organisations and other entities interested in advanced genomic analysis.\n    <\/p>\n\n    <h2>Security, compliance and support<\/h2>\n\n    <p>\n        The SeqOne platform is certified as a Class C CE-IVD in vitro diagnostic medical device under the IVDR. The company is ISO 13485 certified as a medical-device manufacturer and holds ISO 27001, HDS and GDPR certifications for information security and healthcare-data hosting, ensuring secure information management and data protection.\n    <\/p>\n\n    <h2>Key features<\/h2>\n\n    <div class=\"dlw-list\">\n        <span class=\"dlw-list-item\">CE-IVDR bioinformatics platform for somatic NGS analysis in precision oncology.<\/span>\n        <span class=\"dlw-list-item\">End-to-end analysis from raw genomic data to actionable clinical reports.<\/span>\n        <span class=\"dlw-list-item\">Dedicated applications for somatic panels in solid tumours, haemato-oncology\u2014from DNA and RNA\u2014and ctDNA liquid biopsy.<\/span>\n        <span class=\"dlw-list-item\">Detection of SNVs, indels, CNVs, fusions, translocations and other relevant genomic events.<\/span>\n        <span class=\"dlw-list-item\">Variant prioritisation and classification using artificial intelligence and machine learning.<\/span>\n        <span class=\"dlw-list-item\">Integration of annotation databases and international interpretation guidelines.<\/span>\n        <span class=\"dlw-list-item\">LIMS integration and automation of data upload, analysis, quality control and exports.<\/span>\n    <\/div>\n<\/div>\n\n<div\n    id=\"dlwImageModal\"\n    class=\"dlw-modal\"\n    role=\"dialog\"\n    aria-modal=\"true\"\n    aria-label=\"Enlarged image view\"\n    onclick=\"closeDlwModalOnBackdrop(event)\"\n>\n    <button\n        type=\"button\"\n        class=\"dlw-modal-close\"\n        aria-label=\"Close image\"\n        onclick=\"closeDlwModal()\"\n    >&times;<\/button>\n\n    <img decoding=\"async\"\n        id=\"dlwModalImage\"\n        class=\"dlw-modal-content\"\n        src=\"\"\n        alt=\"\"\n    >\n<\/div>\n\n<script>\n(function () {\n    var modal = document.getElementById(\"dlwImageModal\");\n    var modalImage = document.getElementById(\"dlwModalImage\");\n\n    window.openDlwModal = function (src, alt) {\n        modalImage.src = src;\n        modalImage.alt = alt || \"Enlarged image\";\n        modal.classList.add(\"dlw-modal-open\");\n        document.body.style.overflow = \"hidden\";\n    };\n\n    window.closeDlwModal = function () {\n        modal.classList.remove(\"dlw-modal-open\");\n        modalImage.src = \"\";\n        document.body.style.overflow = \"\";\n    };\n\n    window.closeDlwModalOnBackdrop = function (event) {\n        if (event.target === modal) {\n            window.closeDlwModal();\n        }\n    };\n\n    document.addEventListener(\"keydown\", function (event) {\n        if (\n            event.key === \"Escape\" &&\n            modal.classList.contains(\"dlw-modal-open\")\n        ) {\n            window.closeDlwModal();\n        }\n    });\n})();\n<\/script>\n","protected":false},"excerpt":{"rendered":"<p>SeqOne is a bioinformatics platform for NGS data analysis in precision oncology, designed to detect, prioritise and interpret somatic variants and generate actionable clinical reports from raw sequencing data. It helps laboratories and healthcare professionals accelerate the interpretation of NGS data through an end-to-end workflow. Detailed description Operating principle SeqOne Genomics is a genomic data [&hellip;]<\/p>\n","protected":false},"featured_media":28309,"template":"","tecnologias":[36],"marcas":[518],"familias":[456,336,490,491],"class_list":["post-28311","productos","type-productos","status-publish","has-post-thumbnail","hentry","tecnologias-next-generation-sequencing-ngs","marcas-seqone_en","familias-software-en","familias-oncohematology","familias-software-en-2","familias-somatic-analysis-solutions"],"_links":{"self":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/28311","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos"}],"about":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/types\/productos"}],"version-history":[{"count":1,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/28311\/revisions"}],"predecessor-version":[{"id":28312,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/28311\/revisions\/28312"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media\/28309"}],"wp:attachment":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media?parent=28311"}],"wp:term":[{"taxonomy":"tecnologias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/tecnologias?post=28311"},{"taxonomy":"marcas","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/marcas?post=28311"},{"taxonomy":"familias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/familias?post=28311"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}