{"id":28345,"date":"2026-09-02T11:01:45","date_gmt":"2026-09-02T11:01:45","guid":{"rendered":"https:\/\/www.dlongwood.com\/?post_type=productos&#038;p=28345"},"modified":"2026-09-02T11:21:26","modified_gmt":"2026-09-02T11:21:26","slug":"sophia-ddm-community-pharmacogenomics-solution","status":"publish","type":"productos","link":"https:\/\/www.dlongwood.com\/en\/product-catalog\/sophia-ddm-community-pharmacogenomics-solution\/","title":{"rendered":"SOPHiA DDM&#x2122; Community Pharmacogenomics Solution"},"content":{"rendered":"\n<style>\n    .dlw-prod-wrapper {\n        --dlw-blue-dark: #003a70;\n        --dlw-blue-cyan: #00a1e0;\n        --dlw-light-bg: #f9fbfd;\n        --dlw-grey-bg: #f4f6f8;\n        --dlw-border: #e1e8f0;\n        --dlw-grey: #939598;\n\n        width: 100% !important;\n        max-width: 720px !important;\n        margin: 0 auto !important;\n        padding: 0 !important;\n        overflow-wrap: break-word;\n        box-sizing: border-box !important;\n        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}\n<\/style>\n\n<div class=\"dlw-prod-wrapper\">\n\n    <div class=\"dlw-intro\">\n        Pharmacogenomics solution for NGS analysis that combines a capture enrichment kit with the analytical capabilities of the SOPHiA DDM&#x2122; platform. It is designed to evaluate and report genomic variants associated with pharmacogenomics in an accelerated manner.\n    <\/div>\n\n    <h2 class=\"dlw-section-title\">Detailed description<\/h2>\n\n    <h3 class=\"dlw-subsection-title\">Operating principle<\/h3>\n\n    <p class=\"dlw-text\">\n        The solution integrates a capture enrichment kit with the bioinformatics analysis of the SOPHiA DDM&#x2122; platform. The panel covers coding and some non-coding regions of 41 genes and 1 pseudogene associated with pharmacogenomics.\n    <\/p>\n\n    <p class=\"dlw-text\">\n        The probe design is highly optimized to ensure a high percentage of <em>on-target<\/em> reads and uniformity of coverage, even in GC-rich regions, including the first exon.\n    <\/p>\n\n    <div class=\"dlw-image-container\">\n        <img decoding=\"async\" src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/09\/Imagen1.webp\" alt=\"Pharmacogenomics solution\" class=\"dlw-prod-img\" onclick=\"openDlwModal(this.src, this.alt)\" title=\"\">\n    <\/div>\n\n    <h3 class=\"dlw-subsection-title\">Clinical applications<\/h3>\n\n    <p class=\"dlw-text\">\n        Product intended for <strong>pharmacogenomic analysis using NGS<\/strong>, allowing the identification and characterization of genetic variants associated with drug response.\n    <\/p>\n\n    <p class=\"dlw-text\">\n        It facilitates the evaluation of relevant genomic information to <strong>support the interpretation of interindividual variability in pharmacological response<\/strong>, through the characterization of genes of pharmacogenomic interest and the determination of genotypes and <em>star alleles<\/em>.\n    <\/p>\n\n    <h3 class=\"dlw-subsection-title\">Benefits<\/h3>\n\n    <div class=\"dlw-list\">\n        <span class=\"dlw-list-item\">\n            Integrated workflow, from target region enrichment to bioinformatics analysis.\n        <\/span>\n\n        <span class=\"dlw-list-item\">\n            Simplifies the detection, annotation and evaluation of pharmacogenomic variants.\n        <\/span>\n\n        <span class=\"dlw-list-item\">\n            Facilitates interpretation through specific filtering and annotation tools.\n        <\/span>\n\n        <span class=\"dlw-list-item\">\n            Generates pharmacogenomics-specific results and output files, including genotypic information for the genes analyzed.\n        <\/span>\n\n        <span class=\"dlw-list-item\">\n            Specialized analysis of complex genes such as <em>CYP2D6<\/em>.\n        <\/span>\n\n        <span class=\"dlw-list-item\">\n            Reduces the time required for the analysis and interpretation of results.\n        <\/span>\n\n        <span class=\"dlw-list-item\">\n            Secure and unlimited data storage.\n        <\/span>\n\n        <span class=\"dlw-list-item\">\n            Access to the SOPHiA GENETICS community, promoting the exchange of knowledge about variants.\n        <\/span>\n    <\/div>\n\n    <h3 class=\"dlw-subsection-title\">Intended audience\/user<\/h3>\n\n    <p class=\"dlw-text\">\n        Intended for molecular genetics, pharmacogenomics and genomic diagnostics laboratories, as well as professionals specializing in the analysis and interpretation of genetic variants related to drug response.\n    <\/p>\n\n    <div class=\"dlw-considerations\">\n        <span class=\"dlw-considerations-title\">Considerations<\/span>\n\n        <div class=\"dlw-list\">\n            <span class=\"dlw-list-item\">\n                <strong>Required starting material:<\/strong> 50 ng of DNA\n            <\/span>\n\n            <span class=\"dlw-list-item\">\n                <strong>Starting sample type:<\/strong> DNA extracted from peripheral blood\n            <\/span>\n        <\/div>\n    <\/div>\n\n    <h2 class=\"dlw-section-title\">Key aspects<\/h2>\n\n    <div class=\"dlw-key-grid\">\n\n        <div class=\"dlw-key-item\">\n            <span class=\"dlw-key-icon\" aria-hidden=\"true\">\u2713<\/span>\n            <span class=\"dlw-key-description\">\n                <strong>Integrated solution<\/strong> for capture enrichment and bioinformatics analysis for pharmacogenomics.\n            <\/span>\n        <\/div>\n\n        <div class=\"dlw-key-item\">\n            <span class=\"dlw-key-icon\" aria-hidden=\"true\">\u2713<\/span>\n            <span class=\"dlw-key-description\">\n                Coverage of <strong>41 genes and 1 pseudogene<\/strong> of pharmacogenomic interest.\n            <\/span>\n        <\/div>\n\n        <div class=\"dlw-key-item\">\n            <span class=\"dlw-key-icon\" aria-hidden=\"true\">\u2713<\/span>\n            <span class=\"dlw-key-description\">\n                Detection of <strong>SNVs, indels, CNVs and <em>star alleles<\/em><\/strong>.\n            <\/span>\n        <\/div>\n\n        <div class=\"dlw-key-item\">\n            <span class=\"dlw-key-icon\" aria-hidden=\"true\">\u2713<\/span>\n            <span class=\"dlw-key-description\">\n                <strong>Specialized module for <em>CYP2D6<\/em><\/strong>, including analysis of CNVs, promoter regions\/UTRs and determination of <em>star alleles<\/em>.\n            <\/span>\n        <\/div>\n\n        <div class=\"dlw-key-item\">\n            <span class=\"dlw-key-icon\" aria-hidden=\"true\">\u2713<\/span>\n            <span class=\"dlw-key-description\">\n                Specific annotation and filtering tools to streamline variant interpretation.\n            <\/span>\n        <\/div>\n\n        <div class=\"dlw-key-item\">\n            <span class=\"dlw-key-icon\" aria-hidden=\"true\">\u2713<\/span>\n            <span class=\"dlw-key-description\">\n                Generation of a <strong>pharmacogenomic report<\/strong> with the genotypic status of the genes included in the panel.\n            <\/span>\n        <\/div>\n\n        <div class=\"dlw-key-item\">\n            <span class=\"dlw-key-icon\" aria-hidden=\"true\">\u2713<\/span>\n            <span class=\"dlw-key-description\">\n                <strong>High analytical performance<\/strong> in terms of sensitivity, precision and specificity.\n            <\/span>\n        <\/div>\n\n        <div class=\"dlw-key-item\">\n            <span class=\"dlw-key-icon\" aria-hidden=\"true\">\u2713<\/span>\n            <span class=\"dlw-key-description\">\n                Secure data storage.\n            <\/span>\n        <\/div>\n\n        <div class=\"dlw-key-item\">\n            <span class=\"dlw-key-icon\" aria-hidden=\"true\">\u2713<\/span>\n            <span class=\"dlw-key-description\">\n                Integration with the <strong>SOPHiA GENETICS community<\/strong> to facilitate the exchange of knowledge about variants.\n            <\/span>\n        <\/div>\n\n    <\/div>\n\n    <h2 class=\"dlw-section-title\">Presentation details<\/h2>\n\n    <div class=\"dlw-product-code\">\n        <strong>Product code:<\/strong> CS2532ILLRGLY10\n    <\/div>\n\n<\/div>\n\n<div id=\"dlwImageModal\" class=\"dlw-modal\" role=\"dialog\" aria-modal=\"true\" aria-label=\"Enlarged image view\" onclick=\"closeDlwModal()\">\n    <button type=\"button\" class=\"dlw-modal-close\" aria-label=\"Close image\" onclick=\"closeDlwModal(); event.stopPropagation();\">\n        \u00d7\n    <\/button>\n\n    <\/div>\n","protected":false},"excerpt":{"rendered":"<p>Pharmacogenomics solution for NGS analysis that combines a capture enrichment kit with the analytical capabilities of the SOPHiA DDM&#x2122; platform. It is designed to evaluate and report genomic variants associated with pharmacogenomics in an accelerated manner. Detailed description Operating principle The solution integrates a capture enrichment kit with the bioinformatics analysis of the SOPHiA DDM&#x2122; [&hellip;]<\/p>\n","protected":false},"featured_media":28342,"template":"","tecnologias":[36],"marcas":[215],"familias":[283,300,441],"class_list":["post-28345","productos","type-productos","status-publish","has-post-thumbnail","hentry","tecnologias-next-generation-sequencing-ngs","marcas-sophia-genetics-en","familias-molecular-genetics","familias-pharmacogenomics","familias-targeted_study_of_specific_pathologies"],"_links":{"self":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/28345","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos"}],"about":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/types\/productos"}],"version-history":[{"count":1,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/28345\/revisions"}],"predecessor-version":[{"id":28346,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/28345\/revisions\/28346"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media\/28342"}],"wp:attachment":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media?parent=28345"}],"wp:term":[{"taxonomy":"tecnologias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/tecnologias?post=28345"},{"taxonomy":"marcas","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/marcas?post=28345"},{"taxonomy":"familias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/familias?post=28345"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}