{"id":28390,"date":"2026-09-03T07:23:56","date_gmt":"2026-09-03T07:23:56","guid":{"rendered":"https:\/\/www.dlongwood.com\/?post_type=productos&#038;p=28390"},"modified":"2026-09-03T07:29:03","modified_gmt":"2026-09-03T07:29:03","slug":"agilent-sureselect-human-all-exon-v8","status":"publish","type":"productos","link":"https:\/\/www.dlongwood.com\/en\/product-catalog\/agilent-sureselect-human-all-exon-v8\/","title":{"rendered":"Agilent SureSelect Human All Exon V8."},"content":{"rendered":"\n<!-- Complete HTML ready for WordPress \/ Bricks -->\n\n<style>\n    .dlw-prod-wrapper {\n        --dlw-blue-dark: #003a70;\n        --dlw-blue-cyan: #00a1e0;\n        --dlw-light-bg: #f9fbfd;\n        --dlw-grey-bg: #f4f6f8;\n        --dlw-border: #e1e8f0;\n\n        width: 100% !important;\n        max-width: 720px !important;\n        margin: 0 auto !important;\n        padding: 0 !important;\n        overflow-wrap: break-word;\n        box-sizing: border-box !important;\n        color: 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RefSeq, CCDS and GENCODE, including the TERT promoter and difficult-to-capture exons.\n    <\/div>\n\n    <h2 class=\"dlw-section-title\">3.- Detailed Description<\/h2>\n\n    <h3 class=\"dlw-subsection-title\">Operating principle<\/h3>\n\n    <p class=\"dlw-text\">\n        SureSelect Human All Exon V8 is based on NGS library preparation and capture enrichment of target regions of the human exome.\n    <\/p>\n\n    <p class=\"dlw-text\">\n        The workflow is compatible with Agilent SureSelect systems and can be integrated into manual or automated protocols, depending on the laboratory configuration.\n    <\/p>\n\n    <h3 class=\"dlw-subsection-title\">Clinical applications<\/h3>\n\n    <p class=\"dlw-text\">\n        Product intended for laboratories performing exome sequencing in genomic research, clinical genetics or molecular biology projects, especially when broad and uniform coverage of human coding regions is required.\n    <\/p>\n\n    <h3 class=\"dlw-subsection-title\">Benefits<\/h3>\n\n    <div class=\"dlw-list\">\n        <span class=\"dlw-list-item\">\n            <strong>Complete and updated coverage of coding regions<\/strong> from RefSeq, CCDS and GENCODE, including the TERT promoter and difficult-to-capture exons.\n        <\/span>\n\n        <span class=\"dlw-list-item\">\n            <strong>Probe design<\/strong> based on machine learning to improve coverage, efficiency and uniformity, including difficult-to-capture exons and the TERT promoter.\n        <\/span>\n\n        <span class=\"dlw-list-item\">\n            <strong>Efficient design<\/strong> size, aimed at reducing sequencing requirements and costs per sample.\n        <\/span>\n\n        <span class=\"dlw-list-item\">\n            <strong>Automation compatibility<\/strong> with the Bravo Automated Liquid Handling Platform and Magnis NGS Prep System.\n        <\/span>\n    <\/div>\n\n    <h3 class=\"dlw-subsection-title\">Results or key indicators<\/h3>\n\n    <div class=\"dlw-list\">\n        <span class=\"dlw-list-item\">\n            <strong>Panel coverage:<\/strong> target region of 35.1 Mb and design size of 41.6 Mb.\n        <\/span>\n\n        <span class=\"dlw-list-item\">\n            <strong>Target sequence coverage<\/strong> in 8-plex captures: 96% of bases \u226520X, 93% \u226530X, 86% \u226540X and 74% \u226550X, with a median read coverage of 63X.\n        <\/span>\n    <\/div>\n\n    <div class=\"dlw-image-container\">\n        <img decoding=\"async\"\n            src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/09\/1-2.webp\"\n            alt=\"Image 1\"\n            class=\"dlw-prod-img\"\n            onclick=\"openDlwModal(this.src, this.alt)\"\n        >\n    <\/div>\n\n    <div class=\"dlw-list\">\n        <span class=\"dlw-list-item\">\n            <strong>Uniform distribution<\/strong> of <strong>coverage<\/strong> across the <strong>GC<\/strong> content spectrum.\n        <\/span>\n    <\/div>\n\n    <div class=\"dlw-image-grid\">\n        <div class=\"dlw-image-grid-item\">\n            <img decoding=\"async\"\n                src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/09\/2-1.webp\"\n                alt=\"Image 2\"\n                class=\"dlw-prod-img\"\n                onclick=\"openDlwModal(this.src, this.alt)\"\n            >\n        <\/div>\n\n        <div class=\"dlw-image-grid-item\">\n            <img decoding=\"async\"\n                src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/09\/3-1.webp\"\n                alt=\"Image 3\"\n                class=\"dlw-prod-img\"\n                onclick=\"openDlwModal(this.src, this.alt)\"\n            >\n        <\/div>\n    <\/div>\n\n    <div class=\"dlw-list\">\n        <span class=\"dlw-list-item\">\n            <strong>Coverage of clinical interest:<\/strong>\n        <\/span>\n    <\/div>\n\n    <div class=\"dlw-sublist\">\n        <span class=\"dlw-sublist-item\">\n            100% of the coding content of CCDS, GENCODE and RefSeq.\n        <\/span>\n\n        <span class=\"dlw-sublist-item\">\n            179,645 RefSeq exons \u226520X and 14,168 RefSeq genes \u226520X; in ACMG 59 genes, 1,009 exons \u226520X.\n        <\/span>\n    <\/div>\n\n    <div class=\"dlw-image-container\">\n        <img decoding=\"async\"\n            src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/09\/4-1.webp\"\n            alt=\"Image 4\"\n            class=\"dlw-prod-img\"\n            onclick=\"openDlwModal(this.src, this.alt)\"\n        >\n    <\/div>\n\n    <div class=\"dlw-list\">\n        <span class=\"dlw-list-item\">\n            <strong>Genes associated with rare diseases<\/strong>: 6,003 exons \u226520X, with 24% more genes completely covered at \u226520X\n        <\/span>\n    <\/div>\n\n    <div class=\"dlw-image-container\">\n        <img decoding=\"async\"\n            src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/09\/5-1.webp\"\n            alt=\"Image 5\"\n            class=\"dlw-prod-img\"\n            onclick=\"openDlwModal(this.src, this.alt)\"\n        >\n    <\/div>\n\n    <h3 class=\"dlw-subsection-title\">Technology used<\/h3>\n\n    <p class=\"dlw-text\">\n        The NGS workflow is based on library preparation and capture enrichment using Agilent SureSelect systems.\n    <\/p>\n\n    <div class=\"dlw-list\">\n        <span class=\"dlw-list-item\">\n            Possibility of integration into SureSelectXT HS2, SureSelectXT HS, SureSelectXT Low Input, SureSelectQXT and SureSelectXT legacy workflows\n        <\/span>\n\n        <span class=\"dlw-list-item\">\n            Automation on the Agilent Bravo Automated Liquid Handling platform and Agilent Magnis NGS Prep system.\n        <\/span>\n    <\/div>\n\n    <div class=\"dlw-image-container\">\n        <img decoding=\"async\"\n            src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/09\/6-1.webp\"\n            alt=\"Image 6\"\n            class=\"dlw-prod-img\"\n            onclick=\"openDlwModal(this.src, this.alt)\"\n        >\n    <\/div>\n\n    <h3 class=\"dlw-subsection-title\">Intended audience\/user<\/h3>\n\n    <p class=\"dlw-text\">\n        The product is intended for genetics and molecular biology laboratories that require a scalable whole-exome workflow compatible with automation.\n    <\/p>\n\n    <h3 class=\"dlw-subsection-title\">Considerations or limitations<\/h3>\n\n    <div class=\"dlw-consideration\">\n        <strong>RUO<\/strong> label (<strong>For Research Use Only<\/strong>)\n    <\/div>\n\n    <h2 class=\"dlw-section-title\">4.- Key Aspects<\/h2>\n\n    <div class=\"dlw-key-grid\">\n\n        <div class=\"dlw-key-item\">\n            <span class=\"dlw-key-icon\" aria-hidden=\"true\">\u2713<\/span>\n            <span class=\"dlw-key-text\">\n                Human exome with a target region of 35.1 Mb and an efficient design of 41.6 Mb.\n            <\/span>\n        <\/div>\n\n        <div class=\"dlw-key-item\">\n            <span class=\"dlw-key-icon\" aria-hidden=\"true\">\u2713<\/span>\n            <span class=\"dlw-key-text\">\n                Updated coverage of coding regions from RefSeq, CCDS and GENCODE.\n            <\/span>\n        <\/div>\n\n        <div class=\"dlw-key-item\">\n            <span class=\"dlw-key-icon\" aria-hidden=\"true\">\u2713<\/span>\n            <span class=\"dlw-key-text\">\n                Includes the TERT promoter and difficult-to-capture exons.\n            <\/span>\n        <\/div>\n\n        <div class=\"dlw-key-item\">\n            <span class=\"dlw-key-icon\" aria-hidden=\"true\">\u2713<\/span>\n            <span class=\"dlw-key-text\">\n                Probe design based on machine learning and an optimised manufacturing process.\n            <\/span>\n        <\/div>\n\n        <div class=\"dlw-key-item\">\n            <span class=\"dlw-key-icon\" aria-hidden=\"true\">\u2713<\/span>\n            <span class=\"dlw-key-text\">\n                Uniform coverage across the GC spectrum, supporting the representation of GC-rich and GC-poor regions.\n            <\/span>\n        <\/div>\n\n        <div class=\"dlw-key-item\">\n            <span class=\"dlw-key-icon\" aria-hidden=\"true\">\u2713<\/span>\n            <span class=\"dlw-key-text\">\n                High enrichment performance, with improved sequencing efficiency under the conditions evaluated by Agilent.\n            <\/span>\n        <\/div>\n\n        <div class=\"dlw-key-item\">\n            <span class=\"dlw-key-icon\" aria-hidden=\"true\">\u2713<\/span>\n            <span class=\"dlw-key-text\">\n                Compatible with manual and automated workflows, including Bravo and Magnis.\n            <\/span>\n        <\/div>\n\n    <\/div>\n\n    <div class=\"dlw-image-container\">\n        <img decoding=\"async\"\n            src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/09\/7-1.webp\"\n            alt=\"Image 7\"\n            class=\"dlw-prod-img\"\n            onclick=\"openDlwModal(this.src, this.alt)\"\n        >\n    <\/div>\n\n    <details class=\"dlw-presentation-details\">\n        <summary class=\"dlw-presentation-summary\">\n            5.- Presentation Details\n        <\/summary>\n\n        <div class=\"dlw-presentation-content\">\n\n            <p class=\"dlw-text\">\n                Main formats indicated for SureSelect Human All Exon V8:\n            <\/p>\n\n            <h4 class=\"dlw-table-title\">\n                Compatible with rapid hybridisation\n            <\/h4>\n\n            <div class=\"dlw-table-wrapper\">\n                <table class=\"dlw-table\">\n                    <thead>\n                        <tr>\n                            <th>Product<\/th>\n                            <th>16 Rxns<\/th>\n                            <th>96 Rxns<\/th>\n                            <th>96 Rxns Auto<\/th>\n                        <\/tr>\n                    <\/thead>\n\n                    <tbody>\n                        <tr>\n                            <td data-label=\"Product\">\n                                SureSelect XT HS Human All Exon V8\n                            <\/td>\n                            <td data-label=\"16 Rxns\">5191-6873<\/td>\n                            <td data-label=\"96 Rxns\">5191-6874<\/td>\n                            <td data-label=\"96 Rxns Auto\">5191-6875<\/td>\n                        <\/tr>\n                    <\/tbody>\n                <\/table>\n            <\/div>\n\n            <p class=\"dlw-pre-capture\">*Pre-Capture Formats<\/p>\n\n            <div class=\"dlw-table-wrapper\">\n                <table class=\"dlw-table\">\n                    <thead>\n                        <tr>\n                            <th>Product<\/th>\n                            <th>2 Hybs<\/th>\n                            <th>12 Hybs<\/th>\n                            <th>12 Hybs Auto<\/th>\n                        <\/tr>\n                    <\/thead>\n\n                    <tbody>\n                        <tr>\n                            <td data-label=\"Product\">\n                                SureSelect XT HS PreCap Human All Exon V8\n                            <\/td>\n                            <td data-label=\"2 Hybs\">5191-6876<\/td>\n                            <td data-label=\"12 Hybs\">5191-6877<\/td>\n                            <td data-label=\"12 Hybs Auto\">5191-6878<\/td>\n                        <\/tr>\n                    <\/tbody>\n                <\/table>\n            <\/div>\n\n            <h4 class=\"dlw-table-title\">\n                Compatible with overnight hybridisation\n            <\/h4>\n\n            <div class=\"dlw-table-wrapper\">\n                <table class=\"dlw-table\">\n                    <thead>\n                        <tr>\n                            <th>Product<\/th>\n                            <th>16 Rxns<\/th>\n                            <th>96 Rxns<\/th>\n                            <th>96 Rxns Auto<\/th>\n                        <\/tr>\n                    <\/thead>\n\n                    <tbody>\n                        <tr>\n                            <td data-label=\"Product\">\n                                SureSelect XT Human All Exon V8\n                            <\/td>\n                            <td data-label=\"16 Rxns\">5191-6879<\/td>\n                            <td data-label=\"96 Rxns\">5191-6891<\/td>\n                            <td data-label=\"96 Rxns Auto\">5191-6892<\/td>\n                        <\/tr>\n                    <\/tbody>\n                <\/table>\n            <\/div>\n\n            <p class=\"dlw-pre-capture\">*Pre-Capture Formats<\/p>\n\n            <div class=\"dlw-table-wrapper\">\n                <table class=\"dlw-table\">\n                    <thead>\n                        <tr>\n                            <th>Product<\/th>\n                            <th>2 Hybs<\/th>\n                            <th>12 Hybs<\/th>\n                            <th>12 Hybs Auto<\/th>\n                        <\/tr>\n                    <\/thead>\n\n                    <tbody>\n                        <tr>\n                            <td data-label=\"Product\">\n                                SureSelect XT PreCap Human All Exon V8\n                            <\/td>\n                            <td data-label=\"2 Hybs\">5280-0032<\/td>\n                            <td data-label=\"12 Hybs\">5280-0033<\/td>\n                            <td data-label=\"12 Hybs Auto\">5280-0034<\/td>\n                        <\/tr>\n                    <\/tbody>\n                <\/table>\n            <\/div>\n\n            <h4 class=\"dlw-table-title\">\n                Compatible with Magnis NGS Prep System\n            <\/h4>\n\n            <div class=\"dlw-table-wrapper\">\n                <table class=\"dlw-table\">\n                    <thead>\n                        <tr>\n                            <th>Product<\/th>\n                            <th>32 Rxns<\/th>\n                            <th>96 Rxns<\/th>\n                        <\/tr>\n                    <\/thead>\n\n                    <tbody>\n                        <tr>\n                            <td data-label=\"Product\">\n                                Magnis <strong>SSEL XT HS<\/strong> Human All Exon V8, Rev B\n                            <\/td>\n                            <td data-label=\"32 Rxns\">G9772C<\/td>\n                            <td data-label=\"96 Rxns\">G9772D<\/td>\n                        <\/tr>\n\n                        <tr>\n                            <td data-label=\"Product\">\n                                Magnis <strong>SSEL XT HS2<\/strong> Human All Exon V8, Rev B\n                            <\/td>\n                            <td data-label=\"32 Rxns\">G9774A<\/td>\n                            <td data-label=\"96 Rxns\">G9774B<\/td>\n                        <\/tr>\n                    <\/tbody>\n                <\/table>\n            <\/div>\n\n        <\/div>\n    <\/details>\n\n<\/div>\n\n<!-- Centred pop-up -->\n<div\n    id=\"dlwImageModal\"\n    class=\"dlw-modal\"\n    role=\"dialog\"\n    aria-modal=\"true\"\n    aria-label=\"Enlarged image view\"\n    onclick=\"closeDlwModal()\"\n>\n    <button\n        type=\"button\"\n        class=\"dlw-modal-close\"\n        aria-label=\"Close image\"\n        onclick=\"closeDlwModal(); event.stopPropagation();\"\n    >\n        &times;\n    <\/button>\n\n    <img decoding=\"async\"\n        id=\"dlwModalImage\"\n        class=\"dlw-modal-content\"\n        src=\"\"\n        alt=\"\"\n        onclick=\"closeDlwModal(); event.stopPropagation();\"\n    >\n<\/div>\n\n<script>\n    function openDlwModal(imageSource, imageAlt) {\n        var modal = 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});\n<\/script>\n","protected":false},"excerpt":{"rendered":"<p>High-performance exome for the enrichment of human coding regions, with updated coverage of RefSeq, CCDS and GENCODE, including the TERT promoter and difficult-to-capture exons. 3.- Detailed Description Operating principle SureSelect Human All Exon V8 is based on NGS library preparation and capture enrichment of target regions of the human exome. The workflow is compatible with [&hellip;]<\/p>\n","protected":false},"featured_media":28388,"template":"","tecnologias":[36],"marcas":[526],"familias":[283,297,425],"class_list":["post-28390","productos","type-productos","status-publish","has-post-thumbnail","hentry","tecnologias-next-generation-sequencing-ngs","marcas-agilent-en","familias-molecular-genetics","familias-exomes","familias-hereditary_and_or_rare_diseases"],"_links":{"self":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/28390","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos"}],"about":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/types\/productos"}],"version-history":[{"count":1,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/28390\/revisions"}],"predecessor-version":[{"id":28391,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/28390\/revisions\/28391"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media\/28388"}],"wp:attachment":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media?parent=28390"}],"wp:term":[{"taxonomy":"tecnologias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/tecnologias?post=28390"},{"taxonomy":"marcas","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/marcas?post=28390"},{"taxonomy":"familias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/familias?post=28390"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}