{"id":28412,"date":"2026-09-03T08:02:38","date_gmt":"2026-09-03T08:02:38","guid":{"rendered":"https:\/\/www.dlongwood.com\/?post_type=productos&#038;p=28412"},"modified":"2026-09-03T08:06:21","modified_gmt":"2026-09-03T08:06:21","slug":"oncoselect","status":"publish","type":"productos","link":"https:\/\/www.dlongwood.com\/en\/product-catalog\/oncoselect\/","title":{"rendered":"OncoSELECT\u00ae"},"content":{"rendered":"\n<!-- Complete HTML ready for WordPress \/ Bricks -->\n\n<style>\n    .dlw-prod-wrapper {\n        --dlw-blue-dark: #003a70;\n        --dlw-blue-cyan: #00a1e0;\n        --dlw-light-bg: #f9fbfd;\n        --dlw-grey-bg: #f4f6f8;\n        --dlw-border: #e1e8f0;\n\n        width: 100% !important;\n        max-width: 720px !important;\n        margin: 0 auto !important;\n        padding: 0 !important;\n        overflow-wrap: break-word;\n        box-sizing: border-box !important;\n        color: #333333;\n        font-family: \"Raleway\", Arial, sans-serif;\n        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absolute;\n        z-index: 2;\n        top: 14px;\n        right: 24px;\n        padding: 0;\n        border: 0;\n        background: transparent;\n        color: #ffffff;\n        font-family: Arial, sans-serif;\n        font-size: 42px;\n        font-weight: 300;\n        line-height: 1;\n        cursor: pointer;\n    }\n\n    @keyframes dlwModalFadeIn {\n        from {\n            opacity: 0;\n        }\n\n        to {\n            opacity: 1;\n        }\n    }\n\n    @keyframes dlwImageZoomIn {\n        from {\n            opacity: 0;\n            transform: scale(0.94);\n        }\n\n        to {\n            opacity: 1;\n            transform: scale(1);\n        }\n    }\n\n    @media (max-width: 768px) {\n        .dlw-prod-wrapper {\n            width: 100% !important;\n            max-width: 100% !important;\n        }\n\n        .dlw-prod-wrapper .dlw-intro {\n            padding: 18px !important;\n            text-align: left;\n        }\n\n        .dlw-prod-wrapper h2.dlw-section-title {\n            margin-top: 34px !important;\n            font-size: 25px !important;\n        }\n\n        .dlw-prod-wrapper h3.dlw-subsection-title {\n            font-size: 21px !important;\n        }\n\n        .dlw-prod-wrapper p.dlw-text {\n            text-align: left;\n        }\n\n        .dlw-prod-wrapper .dlw-prod-img {\n            max-width: 100% !important;\n        }\n\n        .dlw-prod-wrapper .dlw-key-grid {\n            grid-template-columns: 1fr;\n            gap: 24px;\n            padding: 28px 22px !important;\n        }\n\n        .dlw-prod-wrapper .dlw-presentation-summary {\n            min-height: 68px;\n            padding: 17px 58px 17px 18px !important;\n            font-size: 21px;\n        }\n\n        .dlw-prod-wrapper .dlw-presentation-summary::before {\n            bottom: 13px;\n            left: 18px;\n            width: 40px;\n        }\n\n        .dlw-prod-wrapper .dlw-presentation-summary::after {\n            right: 17px;\n        }\n\n        .dlw-prod-wrapper .dlw-presentation-content {\n            padding: 22px 18px !important;\n        }\n\n        .dlw-modal {\n            padding: 18px;\n        }\n\n        .dlw-modal-content {\n            max-width: 96vw;\n            max-height: 84vh;\n        }\n\n        .dlw-modal-close {\n            top: 8px;\n            right: 14px;\n        }\n    }\n<\/style>\n\n<div class=\"dlw-prod-wrapper\">\n\n    <div class=\"dlw-intro\">\n        Comprehensive targeted liquid biopsy assay designed to support decision-making in oncology through the analysis of 74 clinically relevant genes. The solution encompasses everything from library preparation reagents to bioinformatics analysis, clinical interpretation and the generation of detailed reports.\n    <\/div>\n\n    <h2 class=\"dlw-section-title\">3.- Detailed Description<\/h2>\n\n    <h3 class=\"dlw-subsection-title\">Operating principle<\/h3>\n\n    <p class=\"dlw-text\">\n        OncoSELECT\u00ae is an advanced liquid biopsy panel based on circulating cell-free DNA (cfDNA) that enables the precise and simultaneous detection of the most relevant genomic alterations in oncology.\n    <\/p>\n\n    <div class=\"dlw-image-container\">\n        <img decoding=\"async\"\n            src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/09\/Imagen-1-1.webp\"\n            alt=\"Image 1\"\n            class=\"dlw-prod-img\"\n            onclick=\"openDlwModal(this.src, this.alt)\"\n        >\n    <\/div>\n\n    <p class=\"dlw-text\">\n        The assay identifies single nucleotide variants (SNVs), insertions and deletions (Indels), variants in the TERT promoter, copy number variations (CNVs), alterations in the homologous recombination repair (HRR) pathway, gene fusions and unusual splicing events.\n    <\/p>\n\n    <div class=\"dlw-image-container\">\n        <img decoding=\"async\"\n            src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/09\/Imagen-2-en.webp\"\n            alt=\"Image 2\"\n            class=\"dlw-prod-img\"\n            onclick=\"openDlwModal(this.src, this.alt)\"\n        >\n    <\/div>\n\n    <p class=\"dlw-text\">\n        The analytical workflow comprises end repair and dA addition to cfDNA, followed by the ligation of universal adapters equipped with unique molecular identifiers (UMIs) for error correction. Following PCR amplification and hybrid capture enrichment, the libraries are sequenced on Illumina platforms. Finally, the raw data are processed through the OncoSELECT\u00ae bioinformatics pipeline (secondary and tertiary analysis), culminating in personalised therapeutic interpretation through the OncoKDM\u00ae platform.\n    <\/p>\n\n    <div class=\"dlw-image-container\">\n        <img decoding=\"async\"\n            src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/09\/Imagen-3-en-copia.webp\"\n            alt=\"Image 3\"\n            class=\"dlw-prod-img\"\n            onclick=\"openDlwModal(this.src, this.alt)\"\n        >\n    <\/div>\n\n    <h3 class=\"dlw-subsection-title\">Clinical applications<\/h3>\n\n    <p class=\"dlw-text\">\n        Genomic tool designed for the non-invasive molecular assessment of solid tumours. In a single test, it enables the detection of actionable molecular markers, the identification of potential therapeutic options (targeted therapies) and the assessment of the spatial and temporal heterogeneity of the oncological disease.\n    <\/p>\n\n    <h3 class=\"dlw-subsection-title\">Benefits<\/h3>\n\n    <div class=\"dlw-list\">\n        <span class=\"dlw-list-item\">\n            <strong>Comprehensive molecular overview:<\/strong> Simultaneous and exhaustive detection of multiple types of genomic alterations from a single blood draw.\n        <\/span>\n\n        <span class=\"dlw-list-item\">\n            <strong>Dynamic design:<\/strong> Continuous optimisation of panel content to reflect the latest advances in biomarkers and oncology guidelines.\n        <\/span>\n\n        <span class=\"dlw-list-item\">\n            <strong>End-to-End solution:<\/strong> Covers the entire process, from sample processing in the laboratory (<em>wet-lab<\/em>) to expert clinical interpretation.\n        <\/span>\n\n        <span class=\"dlw-list-item\">\n            <strong>Operational speed (TAT):<\/strong> Agile workflow that enables the generation of complete and actionable clinical results in approximately 5 days.\n        <\/span>\n    <\/div>\n\n    <h3 class=\"dlw-subsection-title\">Intended audience\/user<\/h3>\n\n    <p class=\"dlw-text\">\n        Molecular diagnostic laboratories, pathology departments and centres specialising in oncology seeking to implement liquid biopsy analysis in their own facilities.\n    <\/p>\n\n    <h3 class=\"dlw-subsection-title\">Technology used<\/h3>\n\n    <p class=\"dlw-text\">\n        The assay is based on NGS hybrid capture enrichment technology, using unique molecular identifiers (UMIs) to ensure maximum sensitivity and specificity in the detection of low allele frequency variants (typical of cfDNA). It is compatible with Illumina sequencing platforms. The clinical interpretation of molecular findings is automatically supported by OncoKDM\u00ae, a proprietary expert-reviewed knowledge base.\n    <\/p>\n\n    <h2 class=\"dlw-section-title\">4.- Key Aspects<\/h2>\n\n    <div class=\"dlw-key-grid\">\n\n        <div class=\"dlw-key-item\">\n            <span class=\"dlw-key-icon\" aria-hidden=\"true\">\u2713<\/span>\n            <span class=\"dlw-key-title\">\n                High-impact targeted design:\n            <\/span>\n            <span class=\"dlw-key-text\">\n                Strategic coverage of 74 cancer-relevant genes, addressing complete coding regions (Whole CDSs), <em>hotspots<\/em>, fusions and genes associated with unusual <em>splicing<\/em>.\n            <\/span>\n        <\/div>\n\n        <div class=\"dlw-key-item\">\n            <span class=\"dlw-key-icon\" aria-hidden=\"true\">\u2713<\/span>\n            <span class=\"dlw-key-title\">\n                Comprehensive genomic detection:\n            <\/span>\n            <span class=\"dlw-key-text\">\n                Identifies SNVs, Indels, CNVs, fusions, <em>splicing<\/em> variants and specific alterations in the TERT promoter.\n            <\/span>\n        <\/div>\n\n        <div class=\"dlw-key-item\">\n            <span class=\"dlw-key-icon\" aria-hidden=\"true\">\u2713<\/span>\n            <span class=\"dlw-key-title\">\n                Superior precision and sensitivity:\n            <\/span>\n            <span class=\"dlw-key-text\">\n                Assay architecture designed to mitigate technical noise and deliver highly reliable results from cfDNA.\n            <\/span>\n        <\/div>\n\n        <div class=\"dlw-key-item\">\n            <span class=\"dlw-key-icon\" aria-hidden=\"true\">\u2713<\/span>\n            <span class=\"dlw-key-title\">\n                Sequencing compatibility:\n            <\/span>\n            <span class=\"dlw-key-text\">\n                Validated for multiple platforms in the Illumina family, including NextSeq 500\/550, NextSeq 1000\/2000, NovaSeq 6000 and NovaSeq X.\n            <\/span>\n        <\/div>\n\n        <div class=\"dlw-key-item\">\n            <span class=\"dlw-key-icon\" aria-hidden=\"true\">\u2713<\/span>\n            <span class=\"dlw-key-title\">\n                Centralised clinical interpretation:\n            <\/span>\n            <span class=\"dlw-key-text\">\n                Data analysis powered by OncoKDM\u00ae, facilitating the translation of complex genomic data into clinically useful reports in ~5 days.\n            <\/span>\n        <\/div>\n\n    <\/div>\n\n    <details class=\"dlw-presentation-details\">\n        <summary class=\"dlw-presentation-summary\">\n            5.- Presentation Details\n        <\/summary>\n\n        <div class=\"dlw-presentation-content\">\n            <p class=\"dlw-text\">\n                The kit is presented in a format that allows the analysis of 32 samples (up to 4 hybridisations, with 8 samples per hybridisation).\n            <\/p>\n        <\/div>\n    <\/details>\n\n<\/div>\n\n<!-- Centred pop-up -->\n<div\n    id=\"dlwImageModal\"\n    class=\"dlw-modal\"\n    role=\"dialog\"\n    aria-modal=\"true\"\n    aria-label=\"Enlarged image view\"\n    onclick=\"closeDlwModal()\"\n>\n    <button\n        type=\"button\"\n        class=\"dlw-modal-close\"\n        aria-label=\"Close image\"\n        onclick=\"closeDlwModal(); event.stopPropagation();\"\n    >\n        &times;\n    <\/button>\n\n    <img decoding=\"async\"\n        id=\"dlwModalImage\"\n        class=\"dlw-modal-content\"\n        src=\"\"\n        alt=\"\"\n        onclick=\"closeDlwModal(); event.stopPropagation();\"\n    >\n<\/div>\n\n<script>\n    function openDlwModal(imageSource, imageAlt) {\n        var modal = document.getElementById(\"dlwImageModal\");\n        var modalImage = document.getElementById(\"dlwModalImage\");\n\n        if (!modal || !modalImage) {\n            return;\n        }\n\n        modalImage.src = imageSource;\n        modalImage.alt = imageAlt || \"\";\n        modal.classList.add(\"dlw-modal-visible\");\n        document.body.style.overflow = \"hidden\";\n    }\n\n    function closeDlwModal() {\n        var modal = document.getElementById(\"dlwImageModal\");\n        var modalImage = document.getElementById(\"dlwModalImage\");\n\n        if (!modal) {\n            return;\n        }\n\n        modal.classList.remove(\"dlw-modal-visible\");\n        document.body.style.overflow = \"\";\n\n        if (modalImage) {\n            modalImage.src = \"\";\n            modalImage.alt = \"\";\n        }\n    }\n\n    document.addEventListener(\"keydown\", function (event) {\n        if (event.key === \"Escape\") {\n            closeDlwModal();\n        }\n    });\n<\/script>\n","protected":false},"excerpt":{"rendered":"<p>Comprehensive targeted liquid biopsy assay designed to support decision-making in oncology through the analysis of 74 clinically relevant genes. The solution encompasses everything from library preparation reagents to bioinformatics analysis, clinical interpretation and the generation of detailed reports. 3.- Detailed Description Operating principle OncoSELECT\u00ae is an advanced liquid biopsy panel based on circulating cell-free DNA [&hellip;]<\/p>\n","protected":false},"featured_media":28403,"template":"","tecnologias":[36],"marcas":[251],"familias":[347,459],"class_list":["post-28412","productos","type-productos","status-publish","has-post-thumbnail","hentry","tecnologias-next-generation-sequencing-ngs","marcas-oncodna-en","familias-solid-tumor","familias-liquid-biopsy"],"_links":{"self":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/28412","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos"}],"about":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/types\/productos"}],"version-history":[{"count":1,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/28412\/revisions"}],"predecessor-version":[{"id":28413,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/28412\/revisions\/28413"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media\/28403"}],"wp:attachment":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media?parent=28412"}],"wp:term":[{"taxonomy":"tecnologias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/tecnologias?post=28412"},{"taxonomy":"marcas","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/marcas?post=28412"},{"taxonomy":"familias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/familias?post=28412"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}