{"id":28449,"date":"2026-09-03T08:46:31","date_gmt":"2026-09-03T08:46:31","guid":{"rendered":"https:\/\/www.dlongwood.com\/?post_type=productos&#038;p=28449"},"modified":"2026-09-03T11:07:20","modified_gmt":"2026-09-03T11:07:20","slug":"sureselect-cancer-cgp-assay","status":"publish","type":"productos","link":"https:\/\/www.dlongwood.com\/en\/product-catalog\/sureselect-cancer-cgp-assay\/","title":{"rendered":"SureSelect Cancer CGP Assay"},"content":{"rendered":"\n<!-- HTML COMPLETO EN INGL\u00c9S -->\n\n<style>\n@import url('https:\/\/fonts.googleapis.com\/css2?family=Playfair+Display:wght@600;700&family=Raleway:wght@400;500;600;700&display=swap');\n\n.dlw-cgp,.dlw-cgp *{box-sizing:border-box}\n.dlw-cgp{\n  --dark:#003a70;--cyan:#00a1e0;--border:#e1e8f0;\n  width:100%!important;max-width:720px!important;margin:0 auto!important;\n  color:#27313b;font:400 16px\/1.7 Raleway,Arial,sans-serif\n}\n.dlw-cgp h2{\n  margin:42px 0 22px;padding-bottom:10px;color:var(--dark);\n  font:600 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1.25px,transparent 1.25px);\n  background-size:24px 24px\n}\n.dlw-key{position:relative;padding:4px 4px 4px 38px}\n.dlw-key::before{\n  position:absolute;top:2px;left:0;display:flex;align-items:center;\n  justify-content:center;width:24px;height:24px;border-radius:50%;\n  color:#fff;background:#53aae3;font-weight:700;content:\"\u2713\"\n}\n.dlw-key p{margin:0;font-size:14px;line-height:1.6;text-align:left}\n\n\/* DETALLES *\/\n.dlw-details{\n  margin:18px 0 34px;overflow:hidden;background:#fff;\n  border:1px solid var(--border);border-radius:10px\n}\n.dlw-details>summary{\n  position:relative;padding:17px 52px 17px 20px;\n  color:var(--dark);font-weight:700;background:#f9fbfd;\n  cursor:pointer;list-style:none\n}\n.dlw-details>summary::-webkit-details-marker{display:none}\n.dlw-details>summary::after{\n  position:absolute;top:50%;right:20px;color:var(--cyan);\n  font-size:24px;transform:translateY(-50%);content:\"+\"\n}\n.dlw-details[open]>summary::after{content:\"\u2212\"}\n.dlw-details-content{padding:22px 20px 8px;border-top:1px solid var(--border)}\n\n@media(max-width:768px){\n  .dlw-cgp{max-width:100%!important}\n  .dlw-cgp h2{font-size:26px}\n  .dlw-cgp h3{font-size:21px}\n  .dlw-cgp p,.dlw-cgp .dlw-intro{text-align:left!important}\n  .dlw-cgp .dlw-intro{padding:18px 20px!important}\n  .dlw-img-link{max-width:100%}\n  .dlw-native-tabs{padding-top:43px}\n  .dlw-native-tab>summary{\n    height:43px;\n    padding:0 8px;\n    font-size:13px\n  }\n  .dlw-snv-row{grid-template-columns:repeat(3,minmax(0,1fr))}\n  .dlw-cnv-grid,.dlw-trans-grid{\n    grid-template-rows:none;\n    grid-auto-flow:row;\n    grid-template-columns:repeat(2,minmax(0,1fr))\n  }\n  .dlw-snv-row i,.dlw-cnv-grid i,.dlw-trans-grid i{\n    padding:8px;font-size:12px\n  }\n  .dlw-key-grid{grid-template-columns:1fr;padding:18px}\n}\n@media(max-width:420px){\n  .dlw-snv-row{grid-template-columns:repeat(2,minmax(0,1fr))}\n}\n<\/style>\n\n<div id=\"dlw-en-close\"><\/div>\n\n<div class=\"dlw-cgp\">\n\n  <p class=\"dlw-intro\">\n    Targeted-enrichment NGS pan-cancer panel for comprehensive genomic profiling (CGP) of solid tumours. Designed to detect somatic variants at DNA level (SNVs, indels, CNVs, translocations) and RNA level (gene fusions), as well as to assess complex immuno-oncology biomarkers such as tumour mutational burden (TMB), microsatellite instability (MSI) and homologous recombination deficiency (HRD).\n  <\/p>\n\n  <div class=\"dlw-img-wrap\">\n    <a class=\"dlw-img-link\" href=\"#dlw-en-image-1\">\n      <img decoding=\"async\" src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/09\/imagen-1-en-2.webp\" alt=\"SureSelect Cancer CGP Assay\" class=\"dlw-img\" title=\"\">\n    <\/a>\n  <\/div>\n\n  <h2>Detailed Description<\/h2>\n\n  <h3>Operating principle<\/h3>\n\n  <p>\n    The SureSelect Cancer CGP assay uses SureSelect XT HS2 library preparation and target enrichment chemistry, based on hybridisation capture with probes. The system features a highly flexible modular architecture consisting of a 679-gene DNA module and an 80-gene RNA module. These can be processed separately or in parallel, allowing the libraries to be combined for joint sequencing in the same run.\n  <\/p>\n\n  <div class=\"dlw-gene-table\">\n\n    <p class=\"dlw-table-description\">\n      <strong>Table 2.<\/strong> Gene content (DNA) in the SureSelect Cancer CGP assay, which are also available for use in designing SureSelect Cancer Custom panels.\n    <\/p>\n\n    <div class=\"dlw-native-tabs\">\n\n      <details class=\"dlw-native-tab\" name=\"dlw-en-gene-tabs\">\n        <summary>SNVs\/Indels<\/summary>\n\n        <div class=\"dlw-native-panel\">\n          <div class=\"dlw-snv-grid\">\n            <div class=\"dlw-snv-row\"><i>ABL1<\/i><i>BRAF<\/i><i>CRBN<\/i><i>EPHB2<\/i><i>FLI1<\/i><i>HNF1A<\/i><i>KRAS<\/i><i>MYH9<\/i><i>PIAS3<\/i><i>RAB35<\/i><i>SIN3A<\/i><i>TFE3<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>ABL2<\/i><i>BRCA1<\/i><i>CREBBP<\/i><i>EPHB4<\/i><i>FLT1<\/i><i>HNRNPK<\/i><i>LAMP1<\/i><i>MYOD1<\/i><i>PIAS4<\/i><i>RAC1<\/i><i>SLC34A2<\/i><i>TFEB<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>ABR<\/i><i>BRCA2<\/i><i>CRKL<\/i><i>ERBB2<\/i><i>FLT3<\/i><i>HOXB13<\/i><i>LATS1<\/i><i>NAB2<\/i><i>PIK3C2B<\/i><i>RAD21<\/i><i>SLIT2<\/i><i>TFRC<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>ACVR1<\/i><i>BRD4<\/i><i>CRLF2<\/i><i>ERBB3<\/i><i>FLT4<\/i><i>HOXC6<\/i><i>LATS2<\/i><i>NBN<\/i><i>PIK3C2G<\/i><i>RAD50<\/i><i>SLX4<\/i><i>TGFBR1<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>ACVR1B<\/i><i>BRIP1<\/i><i>CSAD<\/i><i>ERBB4<\/i><i>FOXA1<\/i><i>HRAS<\/i><i>LMO1<\/i><i>NCOA2<\/i><i>PIK3C3<\/i><i>RAD51<\/i><i>SMAD2<\/i><i>TGFBR2<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>ACVR2A<\/i><i>BTG1<\/i><i>CSF1R<\/i><i>ERCC1<\/i><i>FOXA2<\/i><i>HSD3B1<\/i><i>LRP1B<\/i><i>NCOA3<\/i><i>PIK3CA<\/i><i>RAD51B<\/i><i>SMAD3<\/i><i>TIPARP<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>ADGRA2<\/i><i>BTG2<\/i><i>CSF3R<\/i><i>ERCC2<\/i><i>FOXL2<\/i><i>HSP90AA1<\/i><i>LTK<\/i><i>NCOR1<\/i><i>PIK3CB<\/i><i>RAD51C<\/i><i>SMAD4<\/i><i>TLR4<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>AJUBA<\/i><i>BTK<\/i><i>CSNK1A1<\/i><i>ERCC3<\/i><i>FOXO1<\/i><i>ICOSLG<\/i><i>LYN<\/i><i>NCOR2<\/i><i>PIK3CD<\/i><i>RAD51D<\/i><i>SMARCA4<\/i><i>TMEM127<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>AKAP9<\/i><i>C11ORF30<\/i><i>CTCF<\/i><i>ERCC4<\/i><i>FOXP1<\/i><i>ID3<\/i><i>LZTR1<\/i><i>NEGR1<\/i><i>PIK3CG<\/i><i>RAD52<\/i><i>SMARCB1<\/i><i>TMPRSS2<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>AKT1<\/i><i>CALR<\/i><i>CTLA4<\/i><i>ERCC5<\/i><i>FRS2<\/i><i>IDH1<\/i><i>MAF<\/i><i>NF1<\/i><i>PIK3R1<\/i><i>RAD54L<\/i><i>SMARCD1<\/i><i>TNFAIP3<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>AKT2<\/i><i>CARD11<\/i><i>CTNNA1<\/i><i>ERG<\/i><i>FUBP1<\/i><i>IDH2<\/i><i>MAGEC3<\/i><i>NF2<\/i><i>PIK3R2<\/i><i>RAF1<\/i><i>SMARCE1<\/i><i>TNFRSF14<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>AKT3<\/i><i>CASP8<\/i><i>CTNNB1<\/i><i>ERRFI1<\/i><i>FYN<\/i><i>IDO1<\/i><i>MAGI2<\/i><i>NFE2L2<\/i><i>PIK3R3<\/i><i>RANBP2<\/i><i>SMC1A<\/i><i>TOP1<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>ALK<\/i><i>CASR<\/i><i>CTRC<\/i><i>ESR1<\/i><i>GABRA6<\/i><i>IDO2<\/i><i>MALT1<\/i><i>NFKB2<\/i><i>PIM1<\/i><i>RARA<\/i><i>SMC3<\/i><i>TOP2A<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>ALOX12B<\/i><i>CBFB<\/i><i>CUL3<\/i><i>ESR2<\/i><i>GATA1<\/i><i>IFNGR1<\/i><i>MAML2<\/i><i>NFKBIA<\/i><i>PIM2<\/i><i>RASA1<\/i><i>SMG1<\/i><i>TP53<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>ALOX15B<\/i><i>CBL<\/i><i>CUL4A<\/i><i>ETS1<\/i><i>GATA2<\/i><i>IFNGR2<\/i><i>MAP2K1<\/i><i>NKX2-1<\/i><i>PIM3<\/i><i>RB1<\/i><i>SMO<\/i><i>TP53BP1<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>AMER1<\/i><i>CBLB<\/i><i>CUL4B<\/i><i>ETV1<\/i><i>GATA3<\/i><i>IGF1<\/i><i>MAP2K2<\/i><i>NKX3-1<\/i><i>PLCG1<\/i><i>RBM10<\/i><i>SNCAIP<\/i><i>TP63<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>ANKRD11<\/i><i>CCND1<\/i><i>CUX1<\/i><i>ETV4<\/i><i>GATA4<\/i><i>IGF1R<\/i><i>MAP2K4<\/i><i>NLRC5<\/i><i>PLCG2<\/i><i>RECQL4<\/i><i>SOCS1<\/i><i>TP73<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>ANKRD26<\/i><i>CCND2<\/i><i>CXCR4<\/i><i>ETV5<\/i><i>GATA6<\/i><i>IGF2<\/i><i>MAP3K1<\/i><i>NOTCH1<\/i><i>PLK2<\/i><i>REL<\/i><i>SOS1<\/i><i>TRAF2<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>APC<\/i><i>CCND3<\/i><i>CYLD<\/i><i>ETV6<\/i><i>GEN1<\/i><i>IKBKE<\/i><i>MAP3K13<\/i><i>NOTCH2<\/i><i>PMAIP1<\/i><i>REST<\/i><i>SOX10<\/i><i>TRAF3<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>APLNR<\/i><i>CCNE1<\/i><i>CYP17A1<\/i><i>EWSR1<\/i><i>GID4<\/i><i>IKZF1<\/i><i>MAP3K14<\/i><i>NOTCH3<\/i><i>PML<\/i><i>RET<\/i><i>SOX17<\/i><i>TRAF7<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>AR<\/i><i>CD22<\/i><i>DAXX<\/i><i>EZH2<\/i><i>GLI1<\/i><i>IKZF3<\/i><i>MAP3K4<\/i><i>NOTCH4<\/i><i>PMS1<\/i><i>RFWD2<\/i><i>SOX2<\/i><i>TSC1<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>ARAF<\/i><i>CD274<\/i><i>DCUN1D1<\/i><i>EZR<\/i><i>GNA11<\/i><i>IL10<\/i><i>MAP3K7<\/i><i>NPM1<\/i><i>PMS2<\/i><i>RFX5<\/i><i>SOX9<\/i><i>TSC2<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>ARFRP1<\/i><i>CD276<\/i><i>DDR1<\/i><i>FAM175A<\/i><i>GNA13<\/i><i>IL6R<\/i><i>MAPK1<\/i><i>NR3C1<\/i><i>PNRC1<\/i><i>RFXAP<\/i><i>SPEN<\/i><i>TSHR<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>ARHGAP26<\/i><i>CD38<\/i><i>DDR2<\/i><i>FAM46C<\/i><i>GNAI2<\/i><i>IL6ST<\/i><i>MAPK3<\/i><i>NRAS<\/i><i>POLD1<\/i><i>RHEB<\/i><i>SPINK1<\/i><i>TYR<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>ARHGAP35<\/i><i>CD44<\/i><i>DDX3X<\/i><i>FANCA<\/i><i>GNAQ<\/i><i>IL7R<\/i><i>MAX<\/i><i>NRG1<\/i><i>POLE<\/i><i>RHOA<\/i><i>SPOP<\/i><i>TYRO3<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>ARID1A<\/i><i>CD58<\/i><i>DDX41<\/i><i>FANCC<\/i><i>GNAS<\/i><i>ING1<\/i><i>MC1R<\/i><i>NSD1<\/i><i>POLQ<\/i><i>RICTOR<\/i><i>SPTA1<\/i><i>U2AF1<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>ARID1B<\/i><i>CD70<\/i><i>DDX5<\/i><i>FANCD2<\/i><i>GPC3<\/i><i>INHA<\/i><i>MCL1<\/i><i>NT5C2<\/i><i>POT1<\/i><i>RIT1<\/i><i>SRC<\/i><i>UGT1A1<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>ARID2<\/i><i>CD74<\/i><i>DEFB134<\/i><i>FANCE<\/i><i>GPS2<\/i><i>INHBA<\/i><i>MDC1<\/i><i>NTHL1<\/i><i>PPARG<\/i><i>RNASEL<\/i><i>SRSF2<\/i><i>UVRAG<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>ARID5B<\/i><i>CD79A<\/i><i>DHX15<\/i><i>FANCF<\/i><i>GRB2<\/i><i>INPP4A<\/i><i>MDM2<\/i><i>NTRK1<\/i><i>PPM1D<\/i><i>RNF43<\/i><i>STAG1<\/i><i>VEGFA<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>ASXL1<\/i><i>CD79B<\/i><i>DHX9<\/i><i>FANCG<\/i><i>GREM1<\/i><i>INPP4B<\/i><i>MDM4<\/i><i>NTRK2<\/i><i>PPP2R1A<\/i><i>ROS1<\/i><i>STAG2<\/i><i>VHL<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>ASXL2<\/i><i>CDC73<\/i><i>DICER1<\/i><i>FANCI<\/i><i>GRIN2A<\/i><i>INSR<\/i><i>MECOM<\/i><i>NTRK3<\/i><i>PPP2R2A<\/i><i>RPL22<\/i><i>STAT1<\/i><i>VTCN1<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>ATM<\/i><i>CDH1<\/i><i>DIS3<\/i><i>FANCL<\/i><i>GRM3<\/i><i>IRF1<\/i><i>MED12<\/i><i>NUP93<\/i><i>PPP4R2<\/i><i>RPL5<\/i><i>STAT3<\/i><i>WHSC1<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>ATR<\/i><i>CDK12<\/i><i>DIS3L2<\/i><i>FANCM<\/i><i>GSK3B<\/i><i>IRF2<\/i><i>MEF2B<\/i><i>NUTM1<\/i><i>PPP6C<\/i><i>RPS6KA4<\/i><i>STAT4<\/i><i>WHSC1L1<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>ATRX<\/i><i>CDK2<\/i><i>DLX1<\/i><i>FAS<\/i><i>H3F3A<\/i><i>IRF4<\/i><i>MEN1<\/i><i>P2RY8<\/i><i>PRAME<\/i><i>RPS6KB1<\/i><i>STAT5A<\/i><i>WISP3<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>AURKA<\/i><i>CDK4<\/i><i>DNAJB1<\/i><i>FAT1<\/i><i>H3F3B<\/i><i>IRS1<\/i><i>MERTK<\/i><i>PAK1<\/i><i>PRC1<\/i><i>RPS6KB2<\/i><i>STAT5B<\/i><i>WRN<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>AURKB<\/i><i>CDK6<\/i><i>DNMT1<\/i><i>FBXO11<\/i><i>H3F3C<\/i><i>IRS2<\/i><i>MET<\/i><i>PAK3<\/i><i>PRDM1<\/i><i>RPTOR<\/i><i>STAT6<\/i><i>WT1<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>AURKC<\/i><i>CDK7<\/i><i>DNMT3A<\/i><i>FBXW7<\/i><i>HDAC1<\/i><i>JAK1<\/i><i>MGA<\/i><i>PAK7<\/i><i>PREX2<\/i><i>RRM1<\/i><i>STK11<\/i><i>XBP1<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>AXIN1<\/i><i>CDK8<\/i><i>DNMT3B<\/i><i>FGF1<\/i><i>HGF<\/i><i>JAK2<\/i><i>MGMT<\/i><i>PALB2<\/i><i>PRKAR1A<\/i><i>RSPO2<\/i><i>STK40<\/i><i>XIAP<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>AXIN2<\/i><i>CDKN1A<\/i><i>DOT1L<\/i><i>FGF10<\/i><i>HIF1A<\/i><i>JAK3<\/i><i>MITF<\/i><i>PARK2<\/i><i>PRKCI<\/i><i>RUNX1<\/i><i>SUFU<\/i><i>XPO1<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>AXL<\/i><i>CDKN1B<\/i><i>DPYD<\/i><i>FGF12<\/i><i>HIST1H1C<\/i><i>JUN<\/i><i>MKNK1<\/i><i>PARP1<\/i><i>PRKDC<\/i><i>RUNX1T1<\/i><i>SUZ12<\/i><i>XRCC2<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>B2M<\/i><i>CDKN1C<\/i><i>E2F3<\/i><i>FGF14<\/i><i>HIST1H2BD<\/i><i>KAT6A<\/i><i>MLH1<\/i><i>PARP2<\/i><i>PRSS1<\/i><i>RXRA<\/i><i>SYK<\/i><i>YAP1<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>BAP1<\/i><i>CDKN2A<\/i><i>EED<\/i><i>FGF19<\/i><i>HIST1H3A<\/i><i>KDM5A<\/i><i>MLLT3<\/i><i>PARP3<\/i><i>PRSS8<\/i><i>RYBP<\/i><i>TAF1<\/i><i>YES1<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>BARD1<\/i><i>CDKN2B<\/i><i>EGFL7<\/i><i>FGF2<\/i><i>HIST1H3B<\/i><i>KDM5C<\/i><i>MPL<\/i><i>PAX3<\/i><i>PSIP1<\/i><i>SDC4<\/i><i>TAF3<\/i><i>ZBTB2<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>BBC3<\/i><i>CDKN2C<\/i><i>EGFR<\/i><i>FGF23<\/i><i>HIST1H3C<\/i><i>KDM6A<\/i><i>MRE11A<\/i><i>PAX5<\/i><i>PSMA1<\/i><i>SDHA<\/i><i>TAP1<\/i><i>ZBTB7A<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>BCL10<\/i><i>CEBPA<\/i><i>EIF1AX<\/i><i>FGF3<\/i><i>HIST1H3D<\/i><i>KDR<\/i><i>MSH2<\/i><i>PAX7<\/i><i>PSMB5<\/i><i>SDHAF2<\/i><i>TAP2<\/i><i>ZFHX3<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>BCL2<\/i><i>CENPA<\/i><i>EIF4A2<\/i><i>FGF4<\/i><i>HIST1H3E<\/i><i>KEAP1<\/i><i>MSH3<\/i><i>PAX8<\/i><i>PSMD1<\/i><i>SDHB<\/i><i>TAPBP<\/i><i>ZFP36L1<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>BCL2L1<\/i><i>CFTR<\/i><i>EIF4E<\/i><i>FGF5<\/i><i>HIST1H3F<\/i><i>KEL<\/i><i>MSH6<\/i><i>PBRM1<\/i><i>PSMG2<\/i><i>SDHC<\/i><i>TBL1XR1<\/i><i>ZMYM2<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>BCL2L11<\/i><i>CHD2<\/i><i>ELAC2<\/i><i>FGF6<\/i><i>HIST1H3G<\/i><i>KIAA1549<\/i><i>MST1<\/i><i>PCBP1<\/i><i>PTCH1<\/i><i>SDHD<\/i><i>TBX3<\/i><i>ZMYM3<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>BCL2L2<\/i><i>CHD4<\/i><i>ELF3<\/i><i>FGF7<\/i><i>HIST1H3H<\/i><i>KIF5B<\/i><i>MST1R<\/i><i>PDCD1<\/i><i>PTEN<\/i><i>SERPINB3<\/i><i>TCEB1<\/i><i>ZNF217<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>BCL6<\/i><i>CHD8<\/i><i>EML4<\/i><i>FGF8<\/i><i>HIST1H3I<\/i><i>KIT<\/i><i>MTAP<\/i><i>PDCD1LG2<\/i><i>PTK2<\/i><i>SERPINB4<\/i><i>TCF12<\/i><i>ZNF703<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>BCOR<\/i><i>CHEK1<\/i><i>EP300<\/i><i>FGF9<\/i><i>HIST1H3J<\/i><i>KLF2<\/i><i>MTOR<\/i><i>PDGFRA<\/i><i>PTPN11<\/i><i>SETBP1<\/i><i>TCF3<\/i><i>ZNF750<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>BCORL1<\/i><i>CHEK2<\/i><i>EPCAM<\/i><i>FGFR1<\/i><i>HIST2H3C<\/i><i>KLF4<\/i><i>MUTYH<\/i><i>PDGFRB<\/i><i>PTPRD<\/i><i>SETD2<\/i><i>TCF7L2<\/i><i>ZRSR2<\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>BCR<\/i><i>CIC<\/i><i>EPHA2<\/i><i>FGFR2<\/i><i>HIST2H3D<\/i><i>KLHL6<\/i><i>MYB<\/i><i>PDK1<\/i><i>PTPRO<\/i><i>SF3B1<\/i><i>TEK<\/i><i><\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>BIRC2<\/i><i>CIITA<\/i><i>EPHA3<\/i><i>FGFR3<\/i><i>HIST3H3<\/i><i>KMT2A<\/i><i>MYC<\/i><i>PDPK1<\/i><i>PTPRS<\/i><i>SGK1<\/i><i>TERC<\/i><i><\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>BIRC3<\/i><i>CKS1B<\/i><i>EPHA5<\/i><i>FGFR4<\/i><i>HLA-A<\/i><i>KMT2B<\/i><i>MYCL<\/i><i>PGR<\/i><i>PTPRT<\/i><i>SH2B3<\/i><i>TERT<\/i><i><\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>BLM<\/i><i>COL17A1<\/i><i>EPHA7<\/i><i>FH<\/i><i>HLA-B<\/i><i>KMT2C<\/i><i>MYCN<\/i><i>PHF6<\/i><i>QKI<\/i><i>SH2D1A<\/i><i>TET1<\/i><i><\/i><\/div>\n            <div class=\"dlw-snv-row\"><i>BMPR1A<\/i><i>CPA1<\/i><i>EPHB1<\/i><i>FLCN<\/i><i>HLA-C<\/i><i>KMT2D<\/i><i>MYD88<\/i><i>PHOX2B<\/i><i>QSER1<\/i><i>SHQ1<\/i><i>TET2<\/i><i><\/i><\/div>\n          <\/div>\n        <\/div>\n      <\/details>\n\n      <details class=\"dlw-native-tab\" name=\"dlw-en-gene-tabs\">\n        <summary>CNV<\/summary>\n\n        <div class=\"dlw-native-panel\">\n          <div class=\"dlw-cnv-grid\">\n            <i>ALK<\/i><i>AR<\/i><i>BARD1<\/i><i>BRAF<\/i><i>BRCA1<\/i><i>BRCA2<\/i>\n            <i>BRIP1<\/i><i>CCND1<\/i><i>CCND2<\/i><i>CCNE1<\/i><i>CD274<\/i><i>CDK4<\/i>\n            <i>CDK6<\/i><i>CDKN2A<\/i><i>EGFR<\/i><i>ERBB2<\/i><i>FGFR1<\/i><i>FGFR2<\/i>\n            <i>FGFR3<\/i><i>KEAP1<\/i><i>KRAS<\/i><i>MDM2<\/i><i>MET<\/i><i>MYC<\/i>\n            <i>MYCN<\/i><i>PALB2<\/i><i>PIK3CA<\/i><i>PTEN<\/i><i>RAD51C<\/i><i>RAD51D<\/i>\n            <i>STK11<\/i><i>TP53<\/i>\n          <\/div>\n        <\/div>\n      <\/details>\n\n      <details class=\"dlw-native-tab\" name=\"dlw-en-gene-tabs\">\n        <summary>Translocations<\/summary>\n\n        <div class=\"dlw-native-panel\">\n          <div class=\"dlw-trans-grid\">\n            <i>ALK: [18, 19]<\/i>\n            <i>BRAF: [8, 9, 10]<\/i>\n            <i>CIC: [18, 19]<\/i>\n            <i>EGFR: [24, 25, 26]<\/i>\n            <i>FGFR1: [3, 4, 5, 6, 7, 8, 9]<\/i>\n            <i>FGFR2: [17]<\/i>\n            <i>FGFR3: [17, 18]<\/i>\n            <i>NTRK1: [8, 9, 10, 11]<\/i>\n            <i>RAF1: [7, 8, 9]<\/i>\n            <i>RET: [7, 10, 11]<\/i>\n            <i>ROS1: [31, 33, 34, 35]<\/i>\n            <i>TMPRSS2: [1, 2, 3, 4]<\/i>\n          <\/div>\n        <\/div>\n      <\/details>\n\n    <\/div>\n  <\/div>\n\n  <p>\n    The workflow integrates unique and dual molecular identifiers (UMIs and UDIs) to maximise analytical reliability through sequencing error correction. It stands out for offering highly robust performance with minimal DNA input requirements, demonstrating excellent enrichment efficiency even in challenging genomic regions (high GC content).\n  <\/p>\n\n  <p>\n    The assay ensures the detection of SNVs, insertions, deletions and CNVs at variant allele frequencies (VAF) down to 5%, and is optionally compatible with enzymatic fragmentation methods.\n  <\/p>\n\n  <h3>Clinical \/ research applications<\/h3>\n\n  <p>\n    Intended for comprehensive genomic profiling of solid tumour oncology samples using a pan-cancer panel, facilitating the study of different tumour types such as lung, breast, prostate, colorectal, gastric, bladder, kidney, melanoma and pancreatic cancer.\n  <\/p>\n\n  <div class=\"dlw-img-wrap\">\n    <a class=\"dlw-img-link\" href=\"#dlw-en-image-3\">\n      <img decoding=\"async\" src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/09\/imagen-3-en.webp\" alt=\"Clinical and research applications of the SureSelect Cancer CGP Assay\" class=\"dlw-img\" title=\"\">\n    <\/a>\n  <\/div>\n\n  <h3>Benefits<\/h3>\n\n  <div class=\"dlw-list\">\n    <span class=\"dlw-list-item\">Globally curated gene content based on cancer databases and leading clinical oncology researchers.<\/span>\n    <span class=\"dlw-list-item\">Modular DNA\/RNA workflow, with the option to analyse the modules separately or together.<\/span>\n    <span class=\"dlw-list-item\">Rapid assay execution: 90-minute hybridisation and generation of sequencing-ready libraries in one day.<\/span>\n    <span class=\"dlw-list-item\">Automation options with the Magnis NGS Prep System and Bravo NGS Workstation to reduce hands-on time, increase productivity and improve reproducibility.<\/span>\n    <span class=\"dlw-list-item\">Compatibility with Agilent data analysis solutions and with in-house or third-party software.<\/span>\n  <\/div>\n\n  <h3>Intended audience \/ User<\/h3>\n\n  <p>\n    Molecular biology laboratories, pathology departments, clinical genetics services and translational oncology groups dedicated to genomic tumour profiling using NGS, requiring an optimised workflow from sample to final report.\n  <\/p>\n\n  <h3>Technology used<\/h3>\n\n  <p>\n    The NGS workflow is based on <strong>SureSelect XT HS2<\/strong> for library preparation and target enrichment through hybridisation capture using SureSelect probes. It includes error-correcting molecular barcodes (<strong>UMIs<\/strong> and <strong>UDIs<\/strong>) and, optionally, an enzymatic fragmentation step.\n  <\/p>\n\n  <div class=\"dlw-img-wrap\">\n    <a class=\"dlw-img-link\" href=\"#dlw-en-image-4\">\n      <img decoding=\"async\" src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/09\/imagen-4-en.webp\" alt=\"SureSelect Cancer CGP Assay workflow\" class=\"dlw-img\" title=\"\">\n    <\/a>\n  <\/div>\n\n  <h2>Key Aspects<\/h2>\n\n  <div class=\"dlw-key-grid\">\n    <div class=\"dlw-key\"><p>Robust pan-cancer design: Interrogates 679 genes at DNA level and 80 genes at RNA level.<\/p><\/div>\n    <div class=\"dlw-key\"><p>Simultaneous and reproducible detection of conventional structural alterations (SNVs, indels, CNVs, translocations and fusions) and advanced immuno-oncology biomarkers (TMB, MSI and HRD).<\/p><\/div>\n    <div class=\"dlw-key\"><p>Highly reliable detection of TMB and MSI, demonstrating excellent correlation with immunohistochemistry (IHC) staining patterns for MMR genes.<\/p><\/div>\n    <div class=\"dlw-key\"><p>Limit of detection (LOD) established at 5% VAF for somatic variants.<\/p><\/div>\n    <div class=\"dlw-key\"><p>High uniformity and deep on-target coverage, enabling accurate variant detection in both solid tissues and circulating cell-free DNA (cfDNA).<\/p><\/div>\n    <div class=\"dlw-key\"><p>Consistent and comparable technical performance regardless of whether the workflow is manual or automated.<\/p><\/div>\n  <\/div>\n\n  <h2>Presentation Details<\/h2>\n\n  <details class=\"dlw-details\">\n    <summary>View formats and ordering references<\/summary>\n\n    <div class=\"dlw-details-content\">\n      <p><strong>Commercial name:<\/strong> SureSelect Cancer CGP Assay<\/p>\n      <p><strong>Product type:<\/strong> Enrichment and library preparation solution.<\/p>\n      <p><strong>Sample type:<\/strong> Tissue (FFPE, fresh, frozen) and cfDNA.<\/p>\n      <p><strong>Label:<\/strong> RUO (Research Use Only).<\/p>\n\n      <p>\n        <strong>Complete Kit References<\/strong><br>\n        (Include SureSelect XT HS2 reagents; enzymatic fragmentation reagents are not included):\n      <\/p>\n\n      <div class=\"dlw-list\">\n        <span class=\"dlw-list-item\">G9965A \u2014 SureSelect Cancer CGP Assay Starter Kit, 16 reactions.<\/span>\n        <span class=\"dlw-list-item\">G9966A \/ G9966B \u2014 SureSelect Cancer CGP Assay DNA+RNA Kit, 96 reactions (Manual \/ Automation).<\/span>\n        <span class=\"dlw-list-item\">G9967A \/ G9967B \/ G9967C \u2014 SureSelect Cancer CGP Assay DNA Kit (16 rxns \/ 96 rxns \/ 96 rxns Automation).<\/span>\n        <span class=\"dlw-list-item\">G9968A \/ G9968B \/ G9968C \u2014 SureSelect Cancer CGP Assay RNA Kit (16 rxns \/ 96 rxns \/ 96 rxns Automation).<\/span>\n      <\/div>\n\n      <p>\n        <strong>References exclusively for the automated Magnis NGS Prep System<\/strong> (Include enzymatic fragmentation reagents):\n      <\/p>\n\n      <div class=\"dlw-list\">\n        <span class=\"dlw-list-item\">G9777A \/ G9777B \u2014 Magnis SureSelect Cancer CGP XT HS2 DNA Kit (32 reactions \/ 96 reactions).<\/span>\n        <span class=\"dlw-list-item\">G9777C \/ G9777D \u2014 Magnis SureSelect Cancer CGP XT HS2 RNA Kit (32 reactions \/ 96 reactions).<\/span>\n      <\/div>\n    <\/div>\n  <\/details>\n\n<\/div>\n\n<div id=\"dlw-en-image-1\" class=\"dlw-lightbox\">\n  <a href=\"#dlw-en-close\" class=\"dlw-lightbox-close\">\n    <img decoding=\"async\" src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/09\/imagen-1-en-2.webp\" alt=\"SureSelect Cancer CGP Assay\" class=\"dlw-lightbox-img\" title=\"\">\n  <\/a>\n  <a href=\"#dlw-en-close\" class=\"dlw-lightbox-x\" aria-label=\"Close\">&times;<\/a>\n<\/div>\n\n<div id=\"dlw-en-image-3\" class=\"dlw-lightbox\">\n  <a href=\"#dlw-en-close\" class=\"dlw-lightbox-close\">\n    <img decoding=\"async\" src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/09\/imagen-3-en.webp\" alt=\"Clinical and research applications\" class=\"dlw-lightbox-img\" title=\"\">\n  <\/a>\n  <a href=\"#dlw-en-close\" class=\"dlw-lightbox-x\" aria-label=\"Close\">&times;<\/a>\n<\/div>\n\n<div id=\"dlw-en-image-4\" class=\"dlw-lightbox\">\n  <a href=\"#dlw-en-close\" class=\"dlw-lightbox-close\">\n    <img decoding=\"async\" src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/09\/imagen-4-en.webp\" alt=\"SureSelect Cancer CGP Assay workflow\" class=\"dlw-lightbox-img\" title=\"\">\n  <\/a>\n  <a href=\"#dlw-en-close\" class=\"dlw-lightbox-x\" aria-label=\"Close\">&times;<\/a>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Targeted-enrichment NGS pan-cancer panel for comprehensive genomic profiling (CGP) of solid tumours. Designed to detect somatic variants at DNA level (SNVs, indels, CNVs, translocations) and RNA level (gene fusions), as well as to assess complex immuno-oncology biomarkers such as tumour mutational burden (TMB), microsatellite instability (MSI) and homologous recombination deficiency (HRD). Detailed Description Operating principle [&hellip;]<\/p>\n","protected":false},"featured_media":28444,"template":"","tecnologias":[36],"marcas":[526],"familias":[347,461,462],"class_list":["post-28449","productos","type-productos","status-publish","has-post-thumbnail","hentry","tecnologias-next-generation-sequencing-ngs","marcas-agilent-en","familias-solid-tumor","familias-hrd-en","familias-pan-cancer"],"_links":{"self":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/28449","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos"}],"about":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/types\/productos"}],"version-history":[{"count":7,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/28449\/revisions"}],"predecessor-version":[{"id":28457,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/28449\/revisions\/28457"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media\/28444"}],"wp:attachment":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media?parent=28449"}],"wp:term":[{"taxonomy":"tecnologias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/tecnologias?post=28449"},{"taxonomy":"marcas","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/marcas?post=28449"},{"taxonomy":"familias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/familias?post=28449"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}