{"id":28536,"date":"2026-10-06T13:25:10","date_gmt":"2026-10-06T13:25:10","guid":{"rendered":"https:\/\/www.dlongwood.com\/?post_type=productos&#038;p=28536"},"modified":"2026-10-06T13:28:18","modified_gmt":"2026-10-06T13:28:18","slug":"genvinset-mthfr-multiplex","status":"publish","type":"productos","link":"https:\/\/www.dlongwood.com\/en\/product-catalog\/genvinset-mthfr-multiplex\/","title":{"rendered":"Genvinset\u00ae MTHFR multiplex"},"content":{"rendered":"\n<!-- Complete HTML ready for WordPress \/ Bricks -->\n\n<style>\n@import url('https:\/\/fonts.googleapis.com\/css2?family=Playfair+Display:wght@500;600&family=Raleway:wght@400;500;600;700&display=swap');\n\n#dlw-mthfr-en,\n#dlw-mthfr-en *,\n#dlw-mthfr-en *::before,\n#dlw-mthfr-en *::after {\n    box-sizing: border-box !important;\n}\n\n#dlw-mthfr-en {\n    --dlw-blue-dark: #003a70;\n    --dlw-blue-cyan: #00a1e0;\n    --dlw-light-bg: #f9fbfd;\n    --dlw-grey-bg: #f4f6f8;\n    --dlw-border: #e1e8f0;\n    --dlw-text: 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23px 19px 25px !important;\n    }\n}\n<\/style>\n\n<div id=\"dlw-mthfr-en\" class=\"dlw-prod-wrapper\">\n\n    <div class=\"dlw-intro\">\n        <p><em>In vitro<\/em> diagnostic kit based on real-time PCR for the simultaneous detection of the A1298C and C677T polymorphisms in the MTHFR gene.<\/p>\n    <\/div>\n\n    <h2>Detailed description<\/h2>\n\n    <h3>Operating principle<\/h3>\n\n    <p>The assay is based on real-time PCR (Real-Time PCR) amplification using TaqMan\u00ae hydrolysis probes. Two primer pairs are used to amplify specific regions of the MTHFR gene containing the A1298C and C677T polymorphisms. Detection is performed using allele-specific probes labelled with different fluorophores, enabling genotypic discrimination.<\/p>\n\n    <h3>Clinical applications<\/h3>\n\n    <p>Auxiliary tool for the diagnosis of disorders associated with the MTHFR gene, especially in cases of idiopathic recurrent pregnancy loss and disorders related to hyperhomocysteinaemia.<\/p>\n\n    <h2>Key aspects and benefits<\/h2>\n\n    <div class=\"dlw-key-panel\">\n        <div class=\"dlw-key-grid\">\n            <div class=\"dlw-key-item\">Simultaneous detection of both polymorphisms (A1298C and C677T) in a single reaction<\/div>\n            <div class=\"dlw-key-item\">Includes internal controls<\/div>\n            <div class=\"dlw-key-item\">High concordance with reference methods<\/div>\n            <div class=\"dlw-key-item\">High reproducibility<\/div>\n        <\/div>\n    <\/div>\n\n    <h3>Key indicators<\/h3>\n\n    <div class=\"dlw-indicators\">\n        <div class=\"dlw-indicator\">\n            <span class=\"dlw-indicator-value\">100%<\/span>\n            <span class=\"dlw-indicator-label\">Diagnostic concordance.<\/span>\n        <\/div>\n\n        <div class=\"dlw-indicator\">\n            <span class=\"dlw-indicator-value\">100%<\/span>\n            <span class=\"dlw-indicator-label\">Repeatability and reproducibility.<\/span>\n        <\/div>\n    <\/div>\n\n    <h3>Intended users<\/h3>\n\n    <p>Technical personnel trained and qualified in molecular biology and genetic analysis in specialised clinical laboratories.<\/p>\n\n    <h3>Considerations or limitations<\/h3>\n\n    <div class=\"dlw-list\">\n        <span class=\"dlw-list-item\">Detects only the A1298C and C677T polymorphisms in the MTHFR gene.<\/span>\n        <span class=\"dlw-list-item\">Variants in primer- or probe-binding regions may affect the interpretation of results.<\/span>\n        <span class=\"dlw-list-item\">The results must be used together with other clinical and laboratory data.<\/span>\n    <\/div>\n\n    <details class=\"dlw-details\">\n        <summary>Presentation details<\/summary>\n\n        <div class=\"dlw-details-content\">\n            <span class=\"dlw-details-heading\">Available references<\/span>\n\n            <div class=\"dlw-reference-grid\">\n                <div class=\"dlw-reference-card\">\n                    <span class=\"dlw-reference-code\">GVS-MTH-M-24<\/span>\n                    <span class=\"dlw-reference-tests\">24 tests.<\/span>\n                <\/div>\n\n                <div class=\"dlw-reference-card\">\n                    <span class=\"dlw-reference-code\">GVS-MTH-M-48<\/span>\n                    <span class=\"dlw-reference-tests\">48 tests.<\/span>\n                <\/div>\n\n                <div class=\"dlw-reference-card\">\n                    <span class=\"dlw-reference-code\">GVS-MTH-M-96<\/span>\n                    <span class=\"dlw-reference-tests\">96 tests (on request).<\/span>\n                <\/div>\n            <\/div>\n\n            <div class=\"dlw-detail-row\">\n                <strong>Kit contents:<\/strong> each kit contains Master Mix, the primer mixture (Primer Mix), controls (WT and MUT), and a reaction blank (Reaction Blank).\n            <\/div>\n\n            <div class=\"dlw-detail-row\">\n                <strong>Storage conditions:<\/strong> Store between -30\u00b0C and -18\u00b0C.\n            <\/div>\n        <\/div>\n    <\/details>\n\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>In vitro diagnostic kit based on real-time PCR for the simultaneous detection of the A1298C and C677T polymorphisms in the MTHFR gene. Detailed description Operating principle The assay is based on real-time PCR (Real-Time PCR) amplification using TaqMan\u00ae hydrolysis probes. Two primer pairs are used to amplify specific regions of the MTHFR gene containing the [&hellip;]<\/p>\n","protected":false},"featured_media":28534,"template":"","tecnologias":[275],"marcas":[225],"familias":[307],"class_list":["post-28536","productos","type-productos","status-publish","has-post-thumbnail","hentry","tecnologias-rt-pcr-en","marcas-blackhills-diagnostic-resources-en","familias-hematology-and-blood-bank"],"_links":{"self":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/28536","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos"}],"about":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/types\/productos"}],"version-history":[{"count":1,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/28536\/revisions"}],"predecessor-version":[{"id":28537,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/28536\/revisions\/28537"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media\/28534"}],"wp:attachment":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media?parent=28536"}],"wp:term":[{"taxonomy":"tecnologias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/tecnologias?post=28536"},{"taxonomy":"marcas","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/marcas?post=28536"},{"taxonomy":"familias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/familias?post=28536"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}