{"id":28559,"date":"2026-10-13T13:16:21","date_gmt":"2026-10-13T13:16:21","guid":{"rendered":"https:\/\/www.dlongwood.com\/?post_type=productos&#038;p=28559"},"modified":"2026-10-13T13:19:20","modified_gmt":"2026-10-13T13:19:20","slug":"forenseq-dna-signature-plus-kit","status":"publish","type":"productos","link":"https:\/\/www.dlongwood.com\/en\/product-catalog\/forenseq-dna-signature-plus-kit\/","title":{"rendered":"ForenSeq\u00ae DNA Signature PLUS Kit"},"content":{"rendered":"\n<!-- Complete HTML ready for WordPress \/ Bricks -->\n\n<style>\n@import url('https:\/\/fonts.googleapis.com\/css2?family=Playfair+Display:wght@500;600&family=Raleway:wght@400;500;600;700&display=swap');\n\n#dlw-signature-plus-en,\n#dlw-signature-plus-en *,\n#dlw-signature-plus-en *::before,\n#dlw-signature-plus-en *::after,\n#dlw-signature-plus-modal-en,\n#dlw-signature-plus-modal-en * {\n    box-sizing: border-box !important;\n}\n\n#dlw-signature-plus-en {\n    --dlw-blue-dark: #003a70;\n    --dlw-blue-cyan: #00a1e0;\n    --dlw-light-bg: #f9fbfd;\n    --dlw-grey-bg: #f4f6f8;\n    --dlw-border: #e1e8f0;\n    --dlw-text: #363b42;\n\n    display: block !important;\n    width: 100% !important;\n    max-width: 720px !important;\n    margin: 0 auto !important;\n    padding: 0 !important;\n    color: var(--dlw-text) !important;\n    font-family: \"Raleway\", Arial, sans-serif !important;\n    font-size: 16px !important;\n    line-height: 1.7 !important;\n    overflow: visible !important;\n}\n\n#dlw-signature-plus-en p {\n    display: block !important;\n    width: 100% !important;\n    margin: 0 0 20px !important;\n    padding: 0 !important;\n    color: var(--dlw-text) !important;\n    font-family: \"Raleway\", Arial, sans-serif !important;\n    font-size: 16px !important;\n    font-weight: 400 !important;\n    line-height: 1.7 !important;\n    text-align: justify !important;\n    overflow-wrap: break-word !important;\n}\n\n#dlw-signature-plus-en strong {\n    color: inherit !important;\n    font-weight: 700 !important;\n}\n\n\/* Initial description *\/\n\n#dlw-signature-plus-en .dlw-intro {\n    display: block !important;\n    width: 100% !important;\n    margin: 0 0 38px !important;\n    padding: 24px 27px !important;\n    border: 0 !important;\n    border-left: 4px solid var(--dlw-blue-cyan) !important;\n    border-radius: 0 8px 8px 0 !important;\n    background: var(--dlw-light-bg) !important;\n    box-shadow: none !important;\n}\n\n#dlw-signature-plus-en .dlw-intro p {\n    margin: 0 0 16px !important;\n    color: #263747 !important;\n    font-size: 16px !important;\n    line-height: 1.75 !important;\n}\n\n#dlw-signature-plus-en .dlw-intro p:last-child {\n    margin-bottom: 0 !important;\n}\n\n\/* Headings *\/\n\n#dlw-signature-plus-en h2 {\n    position: relative !important;\n    display: block !important;\n    width: 100% !important;\n    margin: 42px 0 26px !important;\n    padding: 0 0 13px !important;\n    border: 0 !important;\n    background: 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!important;\n}\n\n#dlw-signature-plus-en .dlw-table tbody {\n    display: table-row-group !important;\n}\n\n#dlw-signature-plus-en .dlw-table tr {\n    display: table-row !important;\n    margin: 0 !important;\n    padding: 0 !important;\n    border: 0 !important;\n}\n\n#dlw-signature-plus-en .dlw-table th,\n#dlw-signature-plus-en .dlw-table td {\n    display: table-cell !important;\n    margin: 0 !important;\n    padding: 14px 15px !important;\n    border: 1px solid var(--dlw-border) !important;\n    color: var(--dlw-text) !important;\n    font-family: \"Raleway\", Arial, sans-serif !important;\n    font-size: 14px !important;\n    line-height: 1.5 !important;\n    text-align: left !important;\n    vertical-align: top !important;\n    white-space: normal !important;\n    overflow-wrap: anywhere !important;\n}\n\n#dlw-signature-plus-en .dlw-table th {\n    color: #ffffff !important;\n    background: var(--dlw-blue-dark) !important;\n    font-weight: 700 !important;\n}\n\n#dlw-signature-plus-en .dlw-table tbody tr:nth-child(even) td {\n    background: var(--dlw-light-bg) !important;\n}\n\n#dlw-signature-plus-en .dlw-table-3col th:nth-child(1),\n#dlw-signature-plus-en .dlw-table-3col td:nth-child(1) {\n    width: 18% !important;\n}\n\n#dlw-signature-plus-en .dlw-table-3col th:nth-child(2),\n#dlw-signature-plus-en .dlw-table-3col td:nth-child(2) {\n    width: 40% !important;\n}\n\n#dlw-signature-plus-en .dlw-table-3col th:nth-child(3),\n#dlw-signature-plus-en .dlw-table-3col td:nth-child(3) {\n    width: 42% !important;\n}\n\n#dlw-signature-plus-en .dlw-table-4col th:nth-child(1),\n#dlw-signature-plus-en .dlw-table-4col td:nth-child(1) {\n    width: 17% !important;\n}\n\n#dlw-signature-plus-en .dlw-table-4col th:nth-child(2),\n#dlw-signature-plus-en .dlw-table-4col td:nth-child(2) {\n    width: 35% !important;\n}\n\n#dlw-signature-plus-en .dlw-table-4col th:nth-child(3),\n#dlw-signature-plus-en .dlw-table-4col td:nth-child(3),\n#dlw-signature-plus-en .dlw-table-4col th:nth-child(4),\n#dlw-signature-plus-en .dlw-table-4col td:nth-child(4) {\n    width: 24% !important;\n}\n\n#dlw-signature-plus-en .dlw-table-caption {\n    display: block !important;\n    width: 100% !important;\n    margin: 10px 0 29px !important;\n    padding: 0 !important;\n    color: #626d78 !important;\n    font-family: \"Raleway\", Arial, sans-serif !important;\n    font-size: 13px !important;\n    font-style: italic !important;\n    line-height: 1.5 !important;\n    text-align: center !important;\n}\n\n\/* Image *\/\n\n#dlw-signature-plus-en .dlw-figure {\n    display: block !important;\n    width: 100% !important;\n    margin: 30px auto 12px !important;\n    padding: 0 !important;\n    text-align: center !important;\n}\n\n#dlw-signature-plus-en .dlw-prod-img {\n    display: block !important;\n    width: auto !important;\n    max-width: 90% !important;\n    height: auto !important;\n    margin: 0 auto !important;\n    padding: 0 !important;\n    border: 0 !important;\n    border-radius: 8px !important;\n    background: #ffffff !important;\n    box-shadow: none !important;\n    object-fit: contain !important;\n    cursor: zoom-in !important;\n}\n\n\/* Lists *\/\n\n#dlw-signature-plus-en .dlw-list {\n    display: flex !important;\n    flex-direction: column !important;\n    gap: 13px !important;\n    width: 100% !important;\n    margin: 19px 0 31px !important;\n    padding: 0 !important;\n}\n\n#dlw-signature-plus-en .dlw-list-item {\n    position: relative !important;\n    display: block !important;\n    width: 100% !important;\n    margin: 0 !important;\n    padding: 0 0 0 30px !important;\n    color: var(--dlw-text) !important;\n    font-family: \"Raleway\", Arial, sans-serif !important;\n    font-size: 16px !important;\n    font-weight: 400 !important;\n    line-height: 1.65 !important;\n    text-align: left !important;\n    overflow-wrap: break-word !important;\n}\n\n#dlw-signature-plus-en 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background-size: 25px 25px !important;\n    overflow: hidden !important;\n}\n\n#dlw-signature-plus-en .dlw-key-grid {\n    display: grid !important;\n    grid-template-columns: repeat(2, minmax(0, 1fr)) !important;\n    gap: 25px 34px !important;\n    width: 100% !important;\n    margin: 0 !important;\n    padding: 0 !important;\n}\n\n#dlw-signature-plus-en .dlw-key-item {\n    position: relative !important;\n    display: block !important;\n    min-width: 0 !important;\n    margin: 0 !important;\n    padding: 0 0 0 39px !important;\n    color: var(--dlw-text) !important;\n    font-family: \"Raleway\", Arial, sans-serif !important;\n    font-size: 15px !important;\n    font-weight: 400 !important;\n    line-height: 1.6 !important;\n    text-align: left !important;\n    overflow-wrap: break-word !important;\n}\n\n#dlw-signature-plus-en .dlw-key-item::before {\n    content: \"\u2713\" !important;\n    position: absolute !important;\n    top: 1px !important;\n    left: 0 !important;\n    display: block !important;\n    width: 25px !important;\n    height: 25px !important;\n    border-radius: 50% !important;\n    color: #ffffff !important;\n    background: #55abe3 !important;\n    font-family: Arial, sans-serif !important;\n    font-size: 15px !important;\n    font-weight: 700 !important;\n    line-height: 25px !important;\n    text-align: center !important;\n}\n\n#dlw-signature-plus-en .dlw-key-item:last-child {\n    grid-column: 1 \/ -1 !important;\n}\n\n\/* Presentation details dropdown *\/\n\n#dlw-signature-plus-en .dlw-details {\n    display: block !important;\n    width: 100% !important;\n    margin: 42px 0 0 !important;\n    padding: 0 !important;\n    border: 1px solid var(--dlw-border) !important;\n    border-radius: 10px !important;\n    background: #ffffff !important;\n    box-shadow: 0 8px 24px rgba(0, 58, 112, 0.07) !important;\n    overflow: hidden !important;\n}\n\n#dlw-signature-plus-en .dlw-details > summary {\n    position: relative !important;\n    display: block !important;\n    width: 100% !important;\n    margin: 0 !important;\n    padding: 21px 62px 21px 24px !important;\n    border: 0 !important;\n    background: var(--dlw-blue-dark) !important;\n    color: #ffffff !important;\n    font-family: \"Playfair Display\", Georgia, serif !important;\n    font-size: 22px !important;\n    font-weight: 500 !important;\n    line-height: 1.3 !important;\n    text-align: left !important;\n    list-style: none !important;\n    cursor: pointer !important;\n}\n\n#dlw-signature-plus-en .dlw-details > summary::-webkit-details-marker {\n    display: none !important;\n}\n\n#dlw-signature-plus-en .dlw-details > summary::after {\n    content: \"+\" !important;\n    position: absolute !important;\n    top: 50% !important;\n    right: 22px !important;\n    display: block !important;\n    width: 30px !important;\n    height: 30px !important;\n    border: 1px solid rgba(255, 255, 255, 0.65) !important;\n    border-radius: 50% !important;\n    color: #ffffff !important;\n    font-family: Arial, sans-serif !important;\n    font-size: 23px !important;\n    font-weight: 400 !important;\n    line-height: 27px !important;\n    text-align: center !important;\n    transform: translateY(-50%) !important;\n}\n\n#dlw-signature-plus-en .dlw-details[open] > summary::after {\n    content: \"\u2212\" !important;\n}\n\n#dlw-signature-plus-en .dlw-details-content {\n    display: block !important;\n    width: 100% !important;\n    margin: 0 !important;\n    padding: 27px 25px 29px !important;\n    background: #ffffff !important;\n}\n\n#dlw-signature-plus-en .dlw-details-content .dlw-table-wrap {\n    margin-top: 0 !important;\n}\n\n#dlw-signature-plus-en .dlw-details-note {\n    display: block !important;\n    width: 100% !important;\n    margin: 24px 0 0 !important;\n    padding: 18px 20px !important;\n    border-left: 3px solid var(--dlw-blue-cyan) !important;\n    background: var(--dlw-grey-bg) !important;\n    color: var(--dlw-text) !important;\n    font-family: \"Raleway\", Arial, sans-serif !important;\n    font-size: 15px !important;\n    line-height: 1.65 !important;\n    text-align: left !important;\n}\n\n\/* Modal *\/\n\n#dlw-signature-plus-modal-en {\n    position: fixed !important;\n    inset: 0 !important;\n    z-index: 2147483647 !important;\n    display: none !important;\n    align-items: center !important;\n    justify-content: center !important;\n    width: 100vw !important;\n    height: 100vh !important;\n    margin: 0 !important;\n    padding: 32px !important;\n    background: rgba(5, 17, 29, 0.9) !important;\n    opacity: 0 !important;\n    visibility: hidden !important;\n}\n\n#dlw-signature-plus-modal-en.dlw-modal-open {\n    display: flex !important;\n    opacity: 1 !important;\n    visibility: visible !important;\n}\n\n#dlw-signature-plus-modal-en .dlw-modal-img {\n    display: block !important;\n    width: auto !important;\n    max-width: 94vw !important;\n    height: auto !important;\n    max-height: 90vh !important;\n    margin: auto !important;\n    padding: 0 !important;\n    border: 0 !important;\n    border-radius: 8px !important;\n    background: #ffffff !important;\n    box-shadow: none !important;\n    object-fit: contain !important;\n    cursor: zoom-out !important;\n}\n\n#dlw-signature-plus-modal-en .dlw-modal-close {\n    position: fixed !important;\n    top: 18px !important;\n    right: 22px !important;\n    z-index: 2 !important;\n    display: block !important;\n    width: 44px !important;\n    height: 44px !important;\n    margin: 0 !important;\n    padding: 0 !important;\n    border: 0 !important;\n    border-radius: 50% !important;\n    color: #003a70 !important;\n    background: #ffffff !important;\n    font-family: Arial, sans-serif !important;\n    font-size: 30px !important;\n    font-weight: 400 !important;\n    line-height: 44px !important;\n    text-align: center !important;\n    cursor: pointer !important;\n    box-shadow: none !important;\n}\n\n\/* Responsive *\/\n\n@media (max-width: 768px) {\n    #dlw-signature-plus-en {\n        width: 100% !important;\n        max-width: 100% !important;\n        font-size: 15px !important;\n    }\n\n    #dlw-signature-plus-en p,\n    #dlw-signature-plus-en .dlw-intro p {\n        font-size: 15px !important;\n        text-align: left !important;\n    }\n\n    #dlw-signature-plus-en .dlw-intro {\n        padding: 21px !important;\n    }\n\n    #dlw-signature-plus-en h2 {\n        font-size: 25px !important;\n    }\n\n    #dlw-signature-plus-en h3 {\n        font-size: 19px !important;\n    }\n\n    #dlw-signature-plus-en .dlw-prod-img {\n        max-width: 100% !important;\n    }\n\n    #dlw-signature-plus-en .dlw-list-item {\n        font-size: 15px !important;\n    }\n\n    #dlw-signature-plus-en .dlw-key-panel {\n        padding: 25px 21px !important;\n    }\n\n    #dlw-signature-plus-en .dlw-key-grid {\n        grid-template-columns: minmax(0, 1fr) !important;\n        gap: 21px !important;\n    }\n\n    #dlw-signature-plus-en .dlw-key-item:last-child {\n        grid-column: auto !important;\n    }\n\n    #dlw-signature-plus-en .dlw-table-wrap {\n        overflow: visible !important;\n    }\n\n    #dlw-signature-plus-en .dlw-table,\n    #dlw-signature-plus-en .dlw-table tbody,\n    #dlw-signature-plus-en .dlw-table tr,\n    #dlw-signature-plus-en .dlw-table td {\n        display: block !important;\n        width: 100% !important;\n    }\n\n    #dlw-signature-plus-en .dlw-table {\n        border: 0 !important;\n        background: transparent !important;\n    }\n\n    #dlw-signature-plus-en .dlw-table thead {\n        display: none !important;\n    }\n\n    #dlw-signature-plus-en .dlw-table tr {\n        margin: 0 0 17px !important;\n        border: 1px solid var(--dlw-border) !important;\n        border-radius: 8px !important;\n        background: #ffffff !important;\n        overflow: hidden !important;\n    }\n\n    #dlw-signature-plus-en .dlw-table td,\n    #dlw-signature-plus-en .dlw-table-3col td,\n    #dlw-signature-plus-en .dlw-table-4col td {\n        position: relative !important;\n        width: 100% !important;\n        min-height: 46px !important;\n        padding: 12px 14px 12px 43% !important;\n        border: 0 !important;\n        border-bottom: 1px solid var(--dlw-border) !important;\n        background: #ffffff !important;\n        font-size: 14px !important;\n    }\n\n    #dlw-signature-plus-en .dlw-table td:last-child {\n        border-bottom: 0 !important;\n    }\n\n    #dlw-signature-plus-en .dlw-table td::before {\n        content: attr(data-label) !important;\n        position: absolute !important;\n        top: 0 !important;\n        bottom: 0 !important;\n        left: 0 !important;\n        display: flex !important;\n        align-items: center !important;\n        width: 39% !important;\n        padding: 10px 12px !important;\n        color: var(--dlw-blue-dark) !important;\n        background: var(--dlw-light-bg) !important;\n        font-family: \"Raleway\", Arial, sans-serif !important;\n        font-size: 13px !important;\n        font-weight: 700 !important;\n        line-height: 1.35 !important;\n    }\n\n    #dlw-signature-plus-en .dlw-details > summary {\n        padding: 19px 58px 19px 20px !important;\n        font-size: 20px !important;\n    }\n\n    #dlw-signature-plus-en .dlw-details-content {\n        padding: 23px 19px 25px !important;\n    }\n\n    #dlw-signature-plus-modal-en {\n        padding: 18px !important;\n    }\n\n    #dlw-signature-plus-modal-en .dlw-modal-img {\n        max-width: 96vw !important;\n        max-height: 86vh !important;\n    }\n}\n\n@media (max-width: 480px) {\n    #dlw-signature-plus-en .dlw-table td,\n    #dlw-signature-plus-en .dlw-table-3col td,\n    #dlw-signature-plus-en .dlw-table-4col td {\n        padding-left: 12px !important;\n        padding-top: 44px !important;\n    }\n\n    #dlw-signature-plus-en .dlw-table td::before {\n        top: 0 !important;\n        right: 0 !important;\n        bottom: auto !important;\n        width: 100% !important;\n        min-height: 34px !important;\n    }\n}\n<\/style>\n\n<div id=\"dlw-signature-plus-en\" class=\"dlw-prod-wrapper\">\n\n    <div class=\"dlw-intro\">\n        <p>ForenSeq\u00ae DNA Signature Plus Kit is a DNA library preparation kit using next-generation sequencing (Next-Generation Sequencing, NGS) for forensic genetics. It enables the analysis, in a single reaction, of STR and SNP markers intended for human identification, forensic case analysis, generation of profiles for databases and kinship testing.<\/p>\n\n        <p>It includes two primer mixes to adapt the content of the analysis: DPMA includes identification markers and DPMB adds phenotype- and ancestry-informative markers to the previous content. The workflow integrates with MiSeq FGx and the corresponding analysis module of ForenSeq\u00ae Universal Analysis Software (UAS).<\/p>\n    <\/div>\n\n    <h2>Detailed description<\/h2>\n\n    <h3>Operating principle<\/h3>\n\n    <p>Based on amplicon technology, ForenSeq\u00ae DNA Signature Plus Kit generates dual-indexed DNA libraries for sequencing on the MiSeq FGx platform. Each sample is combined with a mixture of specific primers labelled for each target sequence. A first multiplex PCR amplifies the selected targets. A second PCR incorporates unique dual indexes (UDI) for each sample and enriches the amplified products. The resulting libraries are purified and normalised using magnetic beads and are finally combined into a pool ready for sequencing. The kit includes all the reagents required for every stage of library preparation, as well as NA24385 control DNA.<\/p>\n\n    <p>This kit enables STR and SNP markers to be amplified in the same reaction, generating a profile that combines different categories of forensic markers and providing two content options (DPMA or DPMB) depending on the objective of the study. The DPMA mix amplifies 27 autosomal STRs, 24 Y-STRs, 7 X-STRs and 94 identity-informative SNPs; the DPMB mix additionally provides 22 phenotype-informative SNPs (eye colour and hair colour) and 56 biogeographical ancestry-informative SNPs.<\/p>\n\n    <div class=\"dlw-table-wrap\">\n        <table class=\"dlw-table dlw-table-3col\">\n            <thead>\n                <tr>\n                    <th>Primer mix<\/th>\n                    <th>Markers included<\/th>\n                    <th>Analysis purpose<\/th>\n                <\/tr>\n            <\/thead>\n            <tbody>\n                <tr>\n                    <td data-label=\"Primer mix\">DPMA<\/td>\n                    <td data-label=\"Markers included\">Autosomal STRs, X-STRs, Y-STRs and identification SNPs<\/td>\n                    <td data-label=\"Analysis purpose\">Genetic profiles, identification studies and kinship testing<\/td>\n                <\/tr>\n                <tr>\n                    <td data-label=\"Primer mix\">DPMB<\/td>\n                    <td data-label=\"Markers included\">DPMA content plus phenotype and ancestry SNPs<\/td>\n                    <td data-label=\"Analysis purpose\">Identification and additional genetic characterisation<\/td>\n                <\/tr>\n            <\/tbody>\n        <\/table>\n    <\/div>\n\n    <div class=\"dlw-table-caption\">Figure 1. Two independent primer mixes to adapt the analysis.<\/div>\n\n    <p>ForenSeq\u00ae DNA Signature Plus Kit is suitable for different types of starting material. It has been validated for purified DNA samples, buccal swab lysates and direct punches from FTA cards. An optional PCR buffer, ForenSeq\u00ae Enhanced PCR1 Buffer (ePCR1), is also available and is specifically designed for samples containing inhibitors such as humic acid or haematin.<\/p>\n\n    <p>The results obtained are analysed using a specific UAS module included on a dedicated server. The server running the independently installed UAS software receives the data and performs the analysis corresponding to the assay: FASTQ generation, alignment, variant calling and reporting of results.<\/p>\n\n    <figure class=\"dlw-figure\">\n        <img decoding=\"async\"\n            src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/10\/Imagen1.webp\"\n            alt=\"Universal Analysis Software. Example of analysis in the Signature Plus-specific module in UAS\"\n            class=\"dlw-prod-img\"\n            onclick=\"openDlwSignaturePlusModalEn(this.src, this.alt)\"\n        >\n    <\/figure>\n\n    <div class=\"dlw-table-caption\">Figure 2. Universal Analysis Software (UAS). Example of analysis in the Signature Plus-specific module in UAS<\/div>\n\n    <p>The MiSeq FGx instrument operates with two reagent cartridges of different capacities, enabling sequencing runs to be optimised according to the number and nature of the samples. Recommendations for forensic cases take into account potential mixtures, less than 1 ng of available DNA or partial degradation. For reference samples, the multiplexing capacity is higher.<\/p>\n\n    <div class=\"dlw-table-wrap\">\n        <table class=\"dlw-table dlw-table-4col\">\n            <thead>\n                <tr>\n                    <th>Primer mix<\/th>\n                    <th>Sample type<\/th>\n                    <th>Micro cartridge<\/th>\n                    <th>Standard cartridge<\/th>\n                <\/tr>\n            <\/thead>\n            <tbody>\n                <tr>\n                    <td data-label=\"Primer mix\">DPMA<\/td>\n                    <td data-label=\"Sample type\">Reference samples<\/td>\n                    <td data-label=\"Micro cartridge\">36 libraries<\/td>\n                    <td data-label=\"Standard cartridge\">96 libraries<\/td>\n                <\/tr>\n                <tr>\n                    <td data-label=\"Primer mix\">DPMA<\/td>\n                    <td data-label=\"Sample type\">Forensic\/critical samples<\/td>\n                    <td data-label=\"Micro cartridge\">12 libraries<\/td>\n                    <td data-label=\"Standard cartridge\">32 libraries<\/td>\n                <\/tr>\n                <tr>\n                    <td data-label=\"Primer mix\">DPMB<\/td>\n                    <td data-label=\"Sample type\">Reference samples<\/td>\n                    <td data-label=\"Micro cartridge\">12 libraries<\/td>\n                    <td data-label=\"Standard cartridge\">32 libraries<\/td>\n                <\/tr>\n                <tr>\n                    <td data-label=\"Primer mix\">DPMB<\/td>\n                    <td data-label=\"Sample type\">Forensic\/critical samples<\/td>\n                    <td data-label=\"Micro cartridge\">12 libraries<\/td>\n                    <td data-label=\"Standard cartridge\">32 libraries<\/td>\n                <\/tr>\n            <\/tbody>\n        <\/table>\n    <\/div>\n\n    <div class=\"dlw-table-caption\">Figure 3. Recommended multiplexing. Maximum number of libraries per pool according to sample type.<\/div>\n\n    <h2>Applications<\/h2>\n\n    <p>The high number of markers, their different nature and their distribution across two different primer mixes make ForenSeq\u00ae DNA Signature Plus a highly versatile kit that can support forensic geneticists in different applications:<\/p>\n\n    <div class=\"dlw-list\">\n        <span class=\"dlw-list-item\">Human identification and complex kinship testing: the set of markers included in DPMA enables genetic profiles to be analysed for identification studies and complex kinship testing.<\/span>\n\n        <span class=\"dlw-list-item\">Additional information with DPMB: it incorporates 22 phenotype-informative SNPs \u2014eye colour and hair colour\u2014 and 56 biogeographical ancestry-informative SNPs that can support identification studies.<\/span>\n\n        <span class=\"dlw-list-item\">Analysis of complex forensic case samples: highly discriminating data can be obtained from 100 pg of DNA.<\/span>\n\n        <span class=\"dlw-list-item\">Detection of minor contributors: present at a proportion below 5% relative to the major contributor.<\/span>\n\n        <span class=\"dlw-list-item\">Analysis of degraded DNA and extracts containing inhibitors: predominance of SNPs with amplicons equal to or shorter than 125 bp and the option to incorporate the specific ePCR buffer.<\/span>\n    <\/div>\n\n    <h3>Intended users<\/h3>\n\n    <p>Forensic genetics, human identification and kinship testing laboratories requiring a high number of markers to resolve complex identification or kinship cases.<\/p>\n\n    <h2>Key aspects<\/h2>\n\n    <div class=\"dlw-key-panel\">\n        <div class=\"dlw-key-grid\">\n            <div class=\"dlw-key-item\">Panel of 230 genetic markers amplified in a single reaction<\/div>\n\n            <div class=\"dlw-key-item\">Multiple marker categories in a single workflow: aSTRs, YSTRS, XSTRs, iSNPs, piSNP and aiSNPs<\/div>\n\n            <div class=\"dlw-key-item\">DPMA for identification; DPMB adds phenotype and ancestry markers.<\/div>\n\n            <div class=\"dlw-key-item\">Recommended input of 1 ng of purified human DNA, with validation down to an input of 100pg<\/div>\n\n            <div class=\"dlw-key-item\">Accepts 2 \u00b5L of buccal lysate directly or one 1.2 mm FTA card punch.<\/div>\n\n            <div class=\"dlw-key-item\">Up to 96 libraries from reference samples and 32 libraries from critical samples with DPMA per run.<\/div>\n\n            <div class=\"dlw-key-item\">Available in 96- and 384-reaction formats; unique dual indexes included.<\/div>\n\n            <div class=\"dlw-key-item\">Hads-on-time 3 h 30 min<\/div>\n\n            <div class=\"dlw-key-item\">Subjected to testing and quality controls against predefined specifications for forensic assays<\/div>\n        <\/div>\n    <\/div>\n\n    <details class=\"dlw-details\">\n        <summary>Presentation details<\/summary>\n\n        <div class=\"dlw-details-content\">\n            <div class=\"dlw-table-wrap\">\n                <table class=\"dlw-table dlw-table-3col\">\n                    <thead>\n                        <tr>\n                            <th>Product<\/th>\n                            <th>Details<\/th>\n                            <th>Reference<\/th>\n                        <\/tr>\n                    <\/thead>\n                    <tbody>\n                        <tr>\n                            <td data-label=\"Product\">ForenSeq DNA Signature PLUS Kit<\/td>\n                            <td data-label=\"Details\">96 reactions<\/td>\n                            <td data-label=\"Reference\">V16000213<\/td>\n                        <\/tr>\n                        <tr>\n                            <td data-label=\"Product\">ForenSeq DNA Signature PLUS Kit<\/td>\n                            <td data-label=\"Details\">384 reactions<\/td>\n                            <td data-label=\"Reference\">V16000214<\/td>\n                        <\/tr>\n                        <tr>\n                            <td data-label=\"Product\">MiSeq FGx\u00ae Reagent Kit<\/td>\n                            <td data-label=\"Details\">25 M reads<\/td>\n                            <td data-label=\"Reference\">15066817<\/td>\n                        <\/tr>\n                        <tr>\n                            <td data-label=\"Product\">MiSeq FGx\u00ae Reagent Micro Kit<\/td>\n                            <td data-label=\"Details\">10M reads<\/td>\n                            <td data-label=\"Reference\">20021681<\/td>\n                        <\/tr>\n                        <tr>\n                            <td data-label=\"Product\">ForenSeq Enhanced PCR1 Buffer System<\/td>\n                            <td data-label=\"Details\"><\/td>\n                            <td data-label=\"Reference\">V16000137<\/td>\n                        <\/tr>\n                    <\/tbody>\n                <\/table>\n            <\/div>\n\n            <div class=\"dlw-details-note\">MiSeq FGx, sequencing reagents, the UAS server and the optional ePCR1 system are supplied separately. The 384-reaction format does not correspond to 384 samples per run.<\/div>\n        <\/div>\n    <\/details>\n\n<\/div>\n\n<div\n    id=\"dlw-signature-plus-modal-en\"\n    role=\"dialog\"\n    aria-modal=\"true\"\n    aria-hidden=\"true\"\n    aria-label=\"Enlarged image view\"\n>\n    <button\n        type=\"button\"\n        class=\"dlw-modal-close\"\n        aria-label=\"Close image\"\n        onclick=\"closeDlwSignaturePlusModalEn()\"\n    >\u00d7<\/button>\n\n    <img decoding=\"async\"\n        src=\"\"\n        alt=\"\"\n        class=\"dlw-modal-img\"\n        id=\"dlw-signature-plus-modal-image-en\"\n        onclick=\"closeDlwSignaturePlusModalEn()\"\n    >\n<\/div>\n\n<script>\n(function () {\n    var modal = document.getElementById(\"dlw-signature-plus-modal-en\");\n    var modalImage = document.getElementById(\"dlw-signature-plus-modal-image-en\");\n    var previousBodyOverflow = \"\";\n\n    if (!modal || !modalImage) {\n        return;\n    }\n\n    if (modal.parentNode !== document.body) {\n        document.body.appendChild(modal);\n    }\n\n    window.openDlwSignaturePlusModalEn = function (source, alternativeText) {\n        previousBodyOverflow = document.body.style.overflow;\n        modalImage.src = source;\n        modalImage.alt = alternativeText || \"\";\n        modal.classList.add(\"dlw-modal-open\");\n        modal.setAttribute(\"aria-hidden\", \"false\");\n        document.body.style.overflow = \"hidden\";\n    };\n\n    window.closeDlwSignaturePlusModalEn = function () {\n        modal.classList.remove(\"dlw-modal-open\");\n        modal.setAttribute(\"aria-hidden\", \"true\");\n        document.body.style.overflow = previousBodyOverflow;\n    };\n\n    modal.addEventListener(\"click\", function (event) {\n        if (event.target === modal) {\n            window.closeDlwSignaturePlusModalEn();\n        }\n    });\n\n    document.addEventListener(\"keydown\", function (event) {\n        if (\n            event.key === \"Escape\" &&\n            modal.classList.contains(\"dlw-modal-open\")\n        ) {\n            window.closeDlwSignaturePlusModalEn();\n        }\n    });\n})();\n<\/script>\n","protected":false},"excerpt":{"rendered":"<p>ForenSeq\u00ae DNA Signature Plus Kit is a DNA library preparation kit using next-generation sequencing (Next-Generation Sequencing, NGS) for forensic genetics. It enables the analysis, in a single reaction, of STR and SNP markers intended for human identification, forensic case analysis, generation of profiles for databases and kinship testing. It includes two primer mixes to adapt [&hellip;]<\/p>\n","protected":false},"featured_media":28495,"template":"","tecnologias":[36],"marcas":[244],"familias":[288],"class_list":["post-28559","productos","type-productos","status-publish","has-post-thumbnail","hentry","tecnologias-next-generation-sequencing-ngs","marcas-verogen-en","familias-forensic-genetics"],"_links":{"self":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/28559","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos"}],"about":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/types\/productos"}],"version-history":[{"count":1,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/28559\/revisions"}],"predecessor-version":[{"id":28560,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/28559\/revisions\/28560"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media\/28495"}],"wp:attachment":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media?parent=28559"}],"wp:term":[{"taxonomy":"tecnologias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/tecnologias?post=28559"},{"taxonomy":"marcas","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/marcas?post=28559"},{"taxonomy":"familias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/familias?post=28559"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}