{"id":28679,"date":"2026-10-20T11:30:54","date_gmt":"2026-10-20T11:30:54","guid":{"rendered":"https:\/\/www.dlongwood.com\/?post_type=productos&#038;p=28679"},"modified":"2026-10-20T12:56:48","modified_gmt":"2026-10-20T12:56:48","slug":"rainsure-digital-pcr-for-oncohematology","status":"publish","type":"productos","link":"https:\/\/www.dlongwood.com\/en\/product-catalog\/rainsure-digital-pcr-for-oncohematology\/","title":{"rendered":"RainSure \u2013 Digital PCR for Oncohematology"},"content":{"rendered":"\n<!-- Complete HTML ready for WordPress \/ Bricks -->\n\n<style>\n@import url('https:\/\/fonts.googleapis.com\/css2?family=Playfair+Display:wght@600;700&family=Raleway:wght@400;500;600;700&display=swap');\n\n#dlw-rainsure-hematology-en {\n    --dlw-blue-dark: #003a70;\n    --dlw-blue-cyan: #00a1e0;\n    --dlw-light-bg: #f9fbfd;\n    --dlw-grey-bg: #f4f6f8;\n    --dlw-border: #e1e8f0;\n    width: 100% !important;\n    max-width: 720px !important;\n    margin: 0 auto !important;\n    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}\n\n    #dlw-rainsure-hematology-en .dlw-table tbody td::before {\n        content: attr(data-label) !important;\n        display: block !important;\n        margin: 0 0 5px !important;\n        color: var(--dlw-blue-cyan) !important;\n        font-size: 11px !important;\n        font-weight: 700 !important;\n        letter-spacing: 0.04em !important;\n        line-height: 1.3 !important;\n        text-transform: uppercase !important;\n    }\n\n    #dlw-rainsure-hematology-en .dlw-pdf-button {\n        width: 100% !important;\n    }\n\n    #dlw-rainsure-modal-en {\n        padding: 16px !important;\n    }\n\n    #dlw-rainsure-modal-en .dlw-modal-image {\n        max-width: 94vw !important;\n        max-height: 84vh !important;\n    }\n\n    #dlw-rainsure-modal-en .dlw-modal-close {\n        top: -17px !important;\n        right: -8px !important;\n        width: 38px !important;\n        height: 38px !important;\n        font-size: 24px !important;\n    }\n}\n<\/style>\n\n<div id=\"dlw-rainsure-hematology-en\" class=\"dlw-prod-wrapper\">\n\n    <p class=\"dlw-lead\">\n        Comprehensive digital PCR (dPCR)-based solution for the quantitative, highly sensitive and low-cost monitoring of genetic mutations and fusions in haematological malignancies, designed for the continuous monitoring of previously identified molecular targets. RainSure offers an extensive catalogue of tests for the individual detection of up to 46 fusions and 121 hotspots.\n    <\/p>\n\n    <section class=\"dlw-section\">\n        <h2 class=\"dlw-section-title\">Detailed Description<\/h2>\n\n        <p>\n            The proposed workflow is based on the concept: &#8220;identify the target and track it&#8221;. Once the patient&#8217;s complete molecular profile has been obtained at the time of diagnosis (for example, through high-throughput sequencing or NGS), the identified molecular targets are monitored over time using RainSure dPCR technology (from DNA or RNA, depending on the target of interest). dPCR precisely and repeatedly measures the amount of mutation or fusion gene that remains present at each patient follow-up visit.\n        <\/p>\n\n        <div class=\"dlw-figure\">\n            <img decoding=\"async\"\n                src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/10\/1en-1.webp\"\n                alt=\"Workflow for identifying and tracking a molecular target using dPCR\"\n                class=\"dlw-prod-img\"\n                loading=\"lazy\"\n                tabindex=\"0\"\n                role=\"button\"\n                aria-label=\"Enlarge image\"\n                onclick=\"dlwRainSureOpenModalEn(this)\"\n                onkeydown=\"if(event.key==='Enter'||event.key===' '){event.preventDefault();dlwRainSureOpenModalEn(this);}\"\n            >\n        <\/div>\n    <\/section>\n\n    <section class=\"dlw-section\">\n        <h2 class=\"dlw-section-title\">Clinical Applications<\/h2>\n\n        <p>\n            It is intended for the detection and monitoring of minimal residual disease (MRD) and the follow-up of haematological malignancies over time, assessing treatment response, the maintenance of remission and the detection of possible relapses or resistance by analysing the temporal evolution of the mutational or fusion burden.\n        <\/p>\n    <\/section>\n\n    <section class=\"dlw-section\">\n        <h2 class=\"dlw-section-title\">Benefits<\/h2>\n\n        <div class=\"dlw-benefit-grid\">\n\n            <div class=\"dlw-benefit-card\">\n                <strong>Early warning:<\/strong> An increasing molecular signal may appear before a morphological relapse, providing the clinical team with time to act.\n            <\/div>\n\n            <div class=\"dlw-benefit-card\">\n                <strong>Long-term sustainability:<\/strong> Repeatedly assessing a known mutation using dPCR is much more cost-effective than repeating a complete genetic panel at every follow-up visit.\n            <\/div>\n\n            <div class=\"dlw-benefit-card\">\n                <strong>High sensitivity:<\/strong> Ability to detect the molecular target at levels of 0.1% &#8211; 0.001%, enabling residual disease to be monitored at very low levels.\n            <\/div>\n\n            <div class=\"dlw-benefit-card\">\n                <strong>Absolute quantification:<\/strong> Copies are detected and quantified directly without the need for standard curves, ensuring the comparability of results between different time points.\n            <\/div>\n\n        <\/div>\n    <\/section>\n\n    <section class=\"dlw-section\">\n        <h2 class=\"dlw-section-title\">Technology Used<\/h2>\n\n        <p>\n            The RainSure RS-32 system uses RainSure&#8217;s patented droplet digital PCR (droplet dPCR) technology. This system automates the entire process, from droplet generation to amplification and signal detection, and features a closed workflow that reduces the risk of contamination while reducing manual intervention and processing times.\n        <\/p>\n\n        <div class=\"dlw-figure\">\n            <img decoding=\"async\"\n                src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/10\/2-4.webp\"\n                alt=\"RainSure RS-32 system\"\n                class=\"dlw-prod-img\"\n                loading=\"lazy\"\n                tabindex=\"0\"\n                role=\"button\"\n                aria-label=\"Enlarge image\"\n                onclick=\"dlwRainSureOpenModalEn(this)\"\n                onkeydown=\"if(event.key==='Enter'||event.key===' '){event.preventDefault();dlwRainSureOpenModalEn(this);}\"\n            >\n        <\/div>\n    <\/section>\n\n    <section class=\"dlw-section\">\n        <h2 class=\"dlw-section-title\">Considerations or Limitations<\/h2>\n\n        <div class=\"dlw-consideration\">\n            <p>\n                Assay sensitivity is not a single instrument specification, but depends on the target being studied, the number of copies present, sample quality and the workflow.\n            <\/p>\n        <\/div>\n    <\/section>\n\n    <section class=\"dlw-section\">\n        <h2 class=\"dlw-section-title\">Key Features<\/h2>\n\n        <div class=\"dlw-key-panel\">\n            <div class=\"dlw-key-grid\">\n\n                <div class=\"dlw-key-item\">\n                    Monitoring of 167 different alterations, independently (1 alteration\/1 kit). Individual solutions for the detection of up to:\n                    <div class=\"dlw-key-sublist\">\n                        <span class=\"dlw-key-subitem\">46 fusion genes<\/span>\n                        <span class=\"dlw-key-subitem\">121 &#8220;hotspot&#8221; mutations (including FLT3, NPM1, JAK2, IDH1\/2, TP53, BCR::ABL1, etc.).<\/span>\n                    <\/div>\n                <\/div>\n\n                <div class=\"dlw-key-item\">\n                    Universal reagent platform compatible with third-party reagents and probes.\n                <\/div>\n\n                <div class=\"dlw-key-item\">\n                    Wide dynamic range of 5 logarithms with a uniform droplet size (CV &le; 3%).\n                <\/div>\n\n                <div class=\"dlw-key-item\">\n                    Sample recovery for verification and the ability to store and re-scan cartridges.\n                <\/div>\n\n            <\/div>\n        <\/div>\n    <\/section>\n\n    <section class=\"dlw-section\">\n        <details class=\"dlw-details\">\n            <summary class=\"dlw-details-summary\">Presentation Details<\/summary>\n\n            <div class=\"dlw-details-content\">\n\n                <div class=\"dlw-table-wrap\">\n                    <table class=\"dlw-table\">\n                        <thead>\n                            <tr>\n                                <th>Product<\/th>\n                                <th>Marking<\/th>\n                                <th>Format<\/th>\n                                <th>Contents<\/th>\n                            <\/tr>\n                        <\/thead>\n\n                        <tbody>\n                            <tr>\n                                <td data-label=\"Product\">Hematology fusion-gene dPCR assays (RUO)*<\/td>\n                                <td data-label=\"Marking\">RUO<\/td>\n                                <td data-label=\"Format\">12 rxn<\/td>\n                                <td data-label=\"Contents\">Individual kits for studying up to 46 different fusion genes.<\/td>\n                            <\/tr>\n\n                            <tr>\n                                <td data-label=\"Product\">Hematology mutation dPCR assays (RUO)*<\/td>\n                                <td data-label=\"Marking\">RUO<\/td>\n                                <td data-label=\"Format\">12 rxn<\/td>\n                                <td data-label=\"Contents\">Individual kits for studying up to 121 different hotspot mutations, distributed across 43 genes.<\/td>\n                            <\/tr>\n\n                            <tr>\n                                <td data-label=\"Product\">BCR ABL p210\/p190 digital PCR one-tube quant test (CE-IVD)<\/td>\n                                <td data-label=\"Marking\">CE-IVD<\/td>\n                                <td data-label=\"Format\">24 rxn<\/td>\n                                <td data-label=\"Contents\">Quantification of the two main fusion transcripts in a single assay. 24-test format.<\/td>\n                            <\/tr>\n\n                            <tr>\n                                <td data-label=\"Product\">Human JAK2 Gene V617F Mutation Detection Kit (CE-IVD)<\/td>\n                                <td data-label=\"Marking\">CE-IVD<\/td>\n                                <td data-label=\"Format\">96 rxn<\/td>\n                                <td data-label=\"Contents\">Quantification of the V617F mutation in the JAK2 gene<\/td>\n                            <\/tr>\n                        <\/tbody>\n                    <\/table>\n                <\/div>\n\n                <div class=\"dlw-pdf-note\">\n                    <div class=\"dlw-pdf-text\">\n                        *All available targets can be consulted in the PDF available at the following link:\n                    <\/div>\n\n                    <div class=\"dlw-pdf-button-wrap\">\n                        <a\n                            href=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/10\/RainSure-KindStar-Hematology-NGSdPCR-complete-solution-V4.pdf\"\n                            class=\"dlw-pdf-button\"\n                            target=\"_blank\"\n                            rel=\"noopener noreferrer\"\n                        >\n                            Available PDF\n                        <\/a>\n                    <\/div>\n                <\/div>\n\n            <\/div>\n        <\/details>\n    <\/section>\n\n<\/div>\n\n<!-- Image lightbox -->\n<div\n    id=\"dlw-rainsure-modal-en\"\n    role=\"dialog\"\n    aria-modal=\"true\"\n    aria-label=\"Enlarged image\"\n    aria-hidden=\"true\"\n    onclick=\"if(event.target===this){dlwRainSureCloseModalEn();}\"\n>\n    <div\n        class=\"dlw-modal-dialog\"\n        onclick=\"if(event.target===this){dlwRainSureCloseModalEn();}\"\n    >\n        <button\n            type=\"button\"\n            class=\"dlw-modal-close\"\n            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RainSure offers an extensive catalogue of tests for the individual detection of up to 46 fusions and 121 hotspots. Detailed Description The proposed workflow [&hellip;]<\/p>\n","protected":false},"featured_media":28672,"template":"","tecnologias":[123],"marcas":[533],"familias":[336,339,337,340],"class_list":["post-28679","productos","type-productos","status-publish","has-post-thumbnail","hentry","tecnologias-digital-pcr","marcas-rainsure-en","familias-oncohematology","familias-lymphoid-line","familias-minimal-residual-disease","familias-myeloid-line"],"_links":{"self":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/28679","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos"}],"about":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/types\/productos"}],"version-history":[{"count":2,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/28679\/revisions"}],"predecessor-version":[{"id":28694,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/28679\/revisions\/28694"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media\/28672"}],"wp:attachment":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media?parent=28679"}],"wp:term":[{"taxonomy":"tecnologias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/tecnologias?post=28679"},{"taxonomy":"marcas","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/marcas?post=28679"},{"taxonomy":"familias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/familias?post=28679"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}