{"id":7790,"date":"2020-01-23T13:12:00","date_gmt":"2020-01-23T13:12:00","guid":{"rendered":"https:\/\/www.dlongwood.com\/cardio-solution\/"},"modified":"2025-03-14T09:22:51","modified_gmt":"2025-03-14T09:22:51","slug":"cardio-solution","status":"publish","type":"productos","link":"https:\/\/www.dlongwood.com\/en\/product-catalog\/cardio-solution\/","title":{"rendered":"Cardio Solution (CAS and CAS extended)"},"content":{"rendered":"\n

Cardiovascular diseases are the leading cause of death worldwide, and represent about 31% of total mortality. The identification of genetic mutations associated with these diseases would contribute to a better diagnosis and risk stratification of patients.<\/p>\n\n\n\n

The Cardio Solution<\/strong> of Sophia Genetics covers the coding (and binding regions) of 31 clinically relevant genes<\/strong>, associated with arrhythmias and cardiomyopathies<\/strong>.<\/p>\n\n\n\n

The kit uses NGS capture technology and is intended for use on Illumina platforms. It also allows the detection of SNV, CNV <\/strong>and Indels<\/strong>, and guarantees a high percentage of readings and uniformity of coverage, even in GC regions.<\/p>\n\n\n\n

\"\"
<\/figcaption><\/figure>\n\n\n\n
\n\n\n\n

A extended version of this panel, CAS extended<\/strong>, is available. It studies a total of 128 genes<\/strong>.<\/p>\n\n\n\n

\n\n\n\n

The results are interpreted in the SOPHiA DDM platform<\/strong>, designed for the analysis and protection of clinical NGS data. This platform analyzes complex genetic data through the detection, annotation and preclassification of genomic variants.<\/p>\n\n\n\n

In addition to the Cardiopathies kit (CAS), other panels are available for clinical diagnosis in areas such as metabolism, oncohematology, nephrology…<\/p>\n\n\n\n