{"id":8244,"date":"2019-12-02T13:35:24","date_gmt":"2019-12-02T13:35:24","guid":{"rendered":"https:\/\/www.dlongwood.com\/fusionplex-lung-v2-3\/"},"modified":"2026-08-24T11:07:38","modified_gmt":"2026-08-24T11:07:38","slug":"fusionplex-lung-v2","status":"publish","type":"productos","link":"https:\/\/www.dlongwood.com\/en\/product-catalog\/fusionplex-lung-v2\/","title":{"rendered":"FusionPlex\u00ae Lung v2"},"content":{"rendered":"\n<!-- Complete English HTML ready for WordPress \/ Bricks -->\n\n<style>\n.dlw-prod-wrapper {\n    --dlw-blue-dark: #003a70;\n    --dlw-blue-cyan: #00a1e0;\n    --dlw-light-bg: #f9fbfd;\n    --dlw-grey-bg: #f4f6f8;\n    --dlw-border: #e1e8f0;\n    --dlw-grey: #939598;\n\n    width: 100% !important;\n    max-width: 720px !important;\n    margin: 0 auto !important;\n    padding: 24px !important;\n    box-sizing: border-box !important;\n    overflow-wrap: anywhere !important;\n    color: #263746 !important;\n    background: #fff !important;\n    font-family: 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It is based\n        on the use of unidirectional gene-specific primers (GSPs) and molecular\n        adapters with unique molecular barcodes (MBCs), which are ligated to\n        the genetic material before amplification. This strategy enables the\n        efficient capture and amplification of DNA, RNA or cfDNA fragments,\n        even in the presence of unknown mutations or highly fragmented\n        sequences.\n    <\/p>\n\n    <div class=\"dlw-image-wrap\">\n        <img decoding=\"async\"\n            src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/08\/Imagen1-1.webp\"\n            alt=\"Diagram of the Anchored Multiplex PCR technology used by the FUSIONPlex Lung v2 panel\"\n            class=\"dlw-prod-img\"\n            loading=\"lazy\"\n            onclick=\"openDlwModal(this.src, this.alt)\"\n        >\n    <\/div>\n\n    <p>\n        The anchored primer architecture supports a flexible design and reduces\n        information loss during library preparation. Combined with Archer&#x2122;\n        Analysis software, AMP&#x2122; enables systematic error correction, read\n        deduplication and accurate quantification of the original molecules,\n        facilitating the detection of point variants, indels, gene fusions and\n        copy number alterations with high sensitivity and specificity.\n    <\/p>\n\n    <span class=\"dlw-application\">Non-small cell lung cancer<\/span>\n\n    <h2>Protocol<\/h2>\n\n    <div class=\"dlw-card\">\n        <h3>Standard version<\/h3>\n        <p>\n            The panel is designed for use with Illumina\u00ae and Ion Torrent&#x2122;\n            sequencers. The efficient workflow is structured around two rounds\n            of multiplex PCR, with library preparation completed in\n            approximately 1.5 days. It requires a minimum amount of RNA or\n            total nucleic acid (TNA), typically between 10 and 250 ng, extracted\n            from FFPE samples or other clinical sources.\n        <\/p>\n    <\/div>\n\n    <div class=\"dlw-card\">\n        <h3>HT version (high throughput)<\/h3>\n        <p>\n            The panel is optimised for high-throughput workflows and Illumina\u00ae\n            sequencers. It enables the simultaneous preparation of multiple\n            libraries in 96-well plates, using a scalable and automatable\n            protocol that retains the sensitivity and accuracy of the standard\n            design. An input amount of between 10 and 200 ng of RNA or TNA per\n            sample is recommended, making it suitable for laboratories with\n            high analytical workloads.\n        <\/p>\n    <\/div>\n\n    <div class=\"dlw-image-wrap\">\n        <img decoding=\"async\"\n            src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/08\/Imagen2-1.webp\"\n            alt=\"FUSIONPlex Lung v2 protocol workflow\"\n            class=\"dlw-prod-img\"\n            loading=\"lazy\"\n            onclick=\"openDlwModal(this.src, this.alt)\"\n        >\n    <\/div>\n\n    <h2>Software<\/h2>\n\n    <div class=\"dlw-list\">\n        <span class=\"dlw-list-item\">\n            <strong>Archer&#x2122; Analysis<\/strong> is a comprehensive bioinformatics\n            platform developed by IDT for the automated analysis of NGS data\n            generated with panels from the Archer\u00ae family, including\n            FUSIONPlex&#x2122;, VARIANTPlex&#x2122; and LIQUIDPlex&#x2122;. It enables comprehensive\n            molecular analyses from DNA or RNA, adapted to each sample type and\n            clinical or research application.\n        <\/span>\n\n        <span class=\"dlw-list-item\">\n            It is compatible with sequencing data from Illumina\u00ae platforms\n            \u2014FUSIONPlex&#x2122;, VARIANTPlex&#x2122; and LIQUIDPlex&#x2122;\u2014 and Ion Torrent&#x2122;\n            \u2014FUSIONPlex&#x2122; only\u2014.\n        <\/span>\n\n        <span class=\"dlw-list-item\">\n            The platform runs pipelines optimised for each technology. For\n            FUSIONPlex&#x2122;, it supports the detection of known and\n            <em>de novo<\/em> gene fusions, splicing variants, exon-skipping\n            events and gene expression levels from RNA.\n        <\/span>\n\n        <span class=\"dlw-list-item\">\n            Archer&#x2122; Analysis provides an intuitive and secure web interface\n            that enables users to view detected variants, apply custom filters,\n            generate automated reports and perform clinical annotation using\n            tools such as ClinVar, COSMIC and Ensembl, among other reference\n            databases.\n        <\/span>\n\n        <span class=\"dlw-list-item\">\n            Designed for regulated environments, it provides complete\n            traceability, reproducible analyses and scalability for\n            laboratories working with advanced genomic profiling in cancer,\n            from research through to clinical applications under RUO or CE-IVD\n            marking, depending on the panel configuration.\n        <\/span>\n    <\/div>\n\n    <h2>Specifications<\/h2>\n\n    <p class=\"dlw-lead\">\n        <strong>Broad detection capabilities:<\/strong> known and\n        <em>de novo<\/em> fusions, splicing variants, SNVs, insertions,\n        deletions and RNA expression.\n    <\/p>\n\n    <div class=\"dlw-image-wrap\">\n        <img decoding=\"async\"\n            src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/08\/Imagen3.webp\"\n            alt=\"Detection capabilities of the FUSIONPlex Lung v2 panel\"\n            class=\"dlw-prod-img\"\n            loading=\"lazy\"\n            onclick=\"openDlwModal(this.src, this.alt)\"\n        >\n    <\/div>\n\n    <div class=\"dlw-feature-list\">\n        <div class=\"dlw-feature\">\n            <strong>AMP&#x2122; technology<\/strong>\n            Improves sensitivity and accuracy in the detection of genetic\n            alterations.\n        <\/div>\n\n        <div class=\"dlw-feature\">\n            <strong>Optimised for FFPE<\/strong>\n            Suitable for low-quality samples.\n        <\/div>\n\n        <div class=\"dlw-feature\">\n            <strong>Starting amount of genetic material<\/strong>\n            Requires only 10 ng of RNA.\n        <\/div>\n\n        <div class=\"dlw-feature\">\n            <strong>Universal compatibility<\/strong>\n            Compatible with Illumina\u00ae and Ion Torrent&#x2122; sequencers.\n        <\/div>\n\n        <div class=\"dlw-feature\">\n            <strong>Bioinformatics support<\/strong>\n            Includes the Archer&#x2122; Analysis platform for data analysis and\n            visualisation.\n        <\/div>\n    <\/div>\n\n    <h2>Complete gene list<\/h2>\n\n    <div class=\"dlw-image-wrap\">\n        <img decoding=\"async\"\n            src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/08\/Imagen4.webp\"\n            alt=\"Complete gene list for the FUSIONPlex Lung v2 panel\"\n            class=\"dlw-prod-img\"\n            loading=\"lazy\"\n            onclick=\"openDlwModal(this.src, this.alt)\"\n        >\n        <span class=\"dlw-image-caption\">\n            Click the image to enlarge the gene list.\n        <\/span>\n    <\/div>\n\n<\/div>\n\n<div\n    id=\"dlwImageModal\"\n    class=\"dlw-modal\"\n    role=\"dialog\"\n    aria-modal=\"true\"\n    aria-label=\"Enlarged image view\"\n    onclick=\"closeDlwModalOnBackdrop(event)\"\n>\n    <button\n        type=\"button\"\n        class=\"dlw-modal-close\"\n        aria-label=\"Close image\"\n        onclick=\"closeDlwModal()\"\n    >&times;<\/button>\n\n    <img decoding=\"async\"\n        id=\"dlwModalImage\"\n        class=\"dlw-modal-content\"\n        src=\"\"\n        alt=\"\"\n    >\n<\/div>\n\n<script>\n(function () {\n    var previousBodyOverflow = \"\";\n\n    window.openDlwModal = function (src, alt) {\n        var modal = document.getElementById(\"dlwImageModal\");\n        var image = document.getElementById(\"dlwModalImage\");\n\n        if (!modal || !image) return;\n\n        image.src = src;\n        image.alt = alt || \"Enlarged image\";\n        previousBodyOverflow = document.body.style.overflow;\n        document.body.style.overflow = \"hidden\";\n        modal.classList.add(\"dlw-modal-open\");\n    };\n\n    window.closeDlwModal = function () {\n        var modal = document.getElementById(\"dlwImageModal\");\n        var image = document.getElementById(\"dlwModalImage\");\n\n        if (!modal) return;\n\n        modal.classList.remove(\"dlw-modal-open\");\n        document.body.style.overflow = previousBodyOverflow;\n\n        if (image) {\n            image.src = \"\";\n            image.alt = \"\";\n        }\n    };\n\n    window.closeDlwModalOnBackdrop = function (event) {\n        if (event.target && event.target.id === \"dlwImageModal\") {\n            window.closeDlwModal();\n        }\n    };\n\n    document.addEventListener(\"keydown\", function (event) {\n        if (event.key === \"Escape\") {\n            window.closeDlwModal();\n        }\n    });\n})();\n<\/script>\n","protected":false},"excerpt":{"rendered":"<p>NGS assay for the study of 17 genes involved in lung cancer.<\/p>\n","protected":false},"featured_media":7591,"template":"","tecnologias":[36],"marcas":[217],"familias":[347,460,469,464],"class_list":["post-8244","productos","type-productos","status-publish","has-post-thumbnail","hentry","tecnologias-next-generation-sequencing-ngs","marcas-archer-dx-en","familias-solid-tumor","familias-fusions","familias-respiratory-system","familias-tumor-types"],"_links":{"self":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/8244","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos"}],"about":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/types\/productos"}],"version-history":[{"count":1,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/8244\/revisions"}],"predecessor-version":[{"id":28245,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/8244\/revisions\/28245"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media\/7591"}],"wp:attachment":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media?parent=8244"}],"wp:term":[{"taxonomy":"tecnologias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/tecnologias?post=8244"},{"taxonomy":"marcas","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/marcas?post=8244"},{"taxonomy":"familias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/familias?post=8244"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}