{"id":8250,"date":"2019-11-07T13:51:48","date_gmt":"2019-11-07T13:51:48","guid":{"rendered":"https:\/\/www.dlongwood.com\/fusionplex-pan-solid-tumor-v2-3\/"},"modified":"2026-08-24T11:16:09","modified_gmt":"2026-08-24T11:16:09","slug":"fusionplex-pan-solid-tumor-v2","status":"publish","type":"productos","link":"https:\/\/www.dlongwood.com\/en\/product-catalog\/fusionplex-pan-solid-tumor-v2\/","title":{"rendered":"FusionPlex\u00ae Pan Solid Tumor v2"},"content":{"rendered":"\n<!-- Complete English HTML ready for WordPress \/ Bricks -->\n\n<style>\n.dlw-prod-wrapper {\n    --dlw-blue-dark: #003a70;\n    --dlw-blue-cyan: #00a1e0;\n    --dlw-light-bg: #f9fbfd;\n    --dlw-grey-bg: #f4f6f8;\n    --dlw-border: #e1e8f0;\n    --dlw-grey: #939598;\n\n    width: 100% !important;\n    max-width: 720px !important;\n    margin: 0 auto !important;\n    padding: 20px !important;\n    box-sizing: border-box !important;\n    overflow-wrap: anywhere;\n    color: #333;\n    font-family: Raleway, Arial, 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!important;\n    text-align: justify;\n}\n\n.dlw-prod-wrapper strong {\n    color: var(--dlw-blue-dark);\n    font-weight: 700;\n}\n\n.dlw-highlight {\n    margin: 20px 0 !important;\n    padding: 18px 20px !important;\n    border-left: 4px solid var(--dlw-blue-cyan) !important;\n    border-radius: 0 8px 8px 0 !important;\n    background: var(--dlw-light-bg) !important;\n}\n\n.dlw-image-block {\n    margin: 26px 0 !important;\n    text-align: center !important;\n}\n\n.dlw-prod-img {\n    display: block !important;\n    width: auto !important;\n    max-width: 90% !important;\n    height: auto !important;\n    margin: 0 auto !important;\n    border-radius: 8px !important;\n    box-shadow: 0 5px 18px rgba(0, 58, 112, 0.13) !important;\n    cursor: zoom-in !important;\n}\n\n.dlw-image-caption {\n    display: block;\n    margin-top: 9px;\n    color: #66727d;\n    font-size: 13px;\n    line-height: 1.4;\n    text-align: center;\n}\n\n.dlw-tumor-list,\n.dlw-card-grid,\n.dlw-feature-grid {\n   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!important;\n    border-radius: 9px !important;\n    background: var(--dlw-light-bg) !important;\n}\n\n.dlw-protocol-card h3 {\n    margin-top: 0 !important;\n}\n\n.dlw-protocol-card p:last-child {\n    margin-bottom: 0 !important;\n}\n\n.dlw-list {\n    display: flex !important;\n    flex-direction: column !important;\n    gap: 10px !important;\n    margin: 16px 0 22px !important;\n}\n\n.dlw-list-item {\n    position: relative;\n    display: block !important;\n    padding: 11px 14px 11px 36px !important;\n    border: 1px solid var(--dlw-border) !important;\n    border-radius: 7px !important;\n    background: var(--dlw-grey-bg) !important;\n    font-size: 15px !important;\n    line-height: 1.5 !important;\n}\n\n.dlw-list-item::before {\n    content: \"\u2022\";\n    position: absolute;\n    top: 9px;\n    left: 16px;\n    color: var(--dlw-blue-cyan);\n    font-size: 22px;\n    line-height: 1;\n}\n\n.dlw-gene-box {\n    margin: 18px 0 !important;\n    padding: 20px !important;\n    border: 1px solid var(--dlw-border) !important;\n    border-radius: 9px !important;\n    background: var(--dlw-grey-bg) !important;\n}\n\n.dlw-gene-box p {\n    margin: 0 !important;\n    color: #253746;\n    font-family: \"Courier New\", monospace !important;\n    font-size: 14px !important;\n    line-height: 1.8 !important;\n    text-align: left !important;\n    word-spacing: 4px;\n}\n\n.dlw-modal {\n    position: fixed !important;\n    z-index: 999999 !important;\n    inset: 0 !important;\n    display: none;\n    align-items: center !important;\n    justify-content: center !important;\n    padding: 24px !important;\n    background: rgba(0, 0, 0, 0.88) !important;\n}\n\n.dlw-modal.dlw-modal-open {\n    display: flex !important;\n}\n\n.dlw-modal-content {\n    display: block !important;\n    max-width: 94vw !important;\n    max-height: 90vh !important;\n    width: auto !important;\n    height: auto !important;\n    border-radius: 6px !important;\n    object-fit: contain !important;\n}\n\n.dlw-modal-close {\n    position: absolute !important;\n    top: 15px !important;\n    right: 22px !important;\n    padding: 0 !important;\n    border: 0 !important;\n    background: transparent !important;\n    color: #fff !important;\n    font-family: Arial, sans-serif !important;\n    font-size: 42px !important;\n    line-height: 1 !important;\n    cursor: pointer !important;\n}\n\n@media (max-width: 768px) {\n    .dlw-prod-wrapper {\n        width: 100% !important;\n        max-width: 100% !important;\n        padding: 16px !important;\n        overflow-x: hidden !important;\n    }\n\n    .dlw-prod-wrapper h2 {\n        font-size: 25px !important;\n    }\n\n    .dlw-prod-wrapper h3 {\n        font-size: 20px !important;\n    }\n\n    .dlw-prod-wrapper p {\n        font-size: 15px !important;\n        text-align: left !important;\n    }\n\n    .dlw-prod-img {\n        max-width: 100% !important;\n    }\n\n    .dlw-tumor-list,\n    .dlw-card-grid,\n    .dlw-feature-grid {\n        grid-template-columns: 1fr !important;\n    }\n\n    .dlw-gene-box {\n        padding: 16px !important;\n    }\n\n    .dlw-gene-box p {\n        font-size: 13px !important;\n    }\n\n    .dlw-modal {\n        padding: 12px !important;\n    }\n}\n<\/style>\n\n<div class=\"dlw-prod-wrapper\">\n\n    <h2>OVERVIEW<\/h2>\n\n    <p>\n        The <strong>FUSIONPlex\u00ae Pan Solid Tumor v2<\/strong> panel is designed for\n        RNA-based next-generation sequencing (NGS) using the patented\n        <strong>Anchored Multiplex PCR (AMP&#x2122;)<\/strong> technology.\n    <\/p>\n\n    <div class=\"dlw-highlight\">\n        <p>\n            <strong>AMP&#x2122; (Anchored Multiplex PCR)<\/strong> is a patented targeted\n            enrichment platform for next-generation sequencing. It uses\n            unidirectional gene-specific primers (GSPs) and molecular adapters\n            containing unique molecular barcodes (MBCs), which are ligated to the\n            genetic material before amplification.\n        <\/p>\n\n        <p>\n            This strategy enables efficient capture and amplification of DNA, RNA\n            or cfDNA fragments, even in the presence of unknown mutations or\n            highly fragmented sequences.\n        <\/p>\n    <\/div>\n\n    <div class=\"dlw-image-block\">\n        <img decoding=\"async\"\n            src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/08\/Imagen1-2.webp\"\n            alt=\"Anchored Multiplex PCR technology workflow\"\n            class=\"dlw-prod-img\"\n            onclick=\"openDlwModal(this.src)\"\n        >\n    <\/div>\n\n    <p>\n        The anchored primer architecture supports a flexible design and reduces\n        information loss during library preparation. Combined with\n        <strong>Archer&#x2122; Analysis<\/strong> software, AMP&#x2122; enables systematic error\n        correction, read deduplication and accurate quantification of the original\n        molecules.\n    <\/p>\n\n    <p>\n        This facilitates the detection of single-nucleotide variants, indels,\n        gene fusions and copy-number alterations with high sensitivity and\n        specificity.\n    <\/p>\n\n    <h2>RECOMMENDED TUMOUR TYPES<\/h2>\n\n    <div class=\"dlw-tumor-list\">\n        <span class=\"dlw-tumor-item\">Colorectal cancer<\/span>\n        <span class=\"dlw-tumor-item\">Breast cancer<\/span>\n        <span class=\"dlw-tumor-item\">Melanoma<\/span>\n        <span class=\"dlw-tumor-item\">Thyroid cancer<\/span>\n        <span class=\"dlw-tumor-item\">Gastric cancer<\/span>\n        <span class=\"dlw-tumor-item\">Pancreatic cancer<\/span>\n        <span class=\"dlw-tumor-item\">Central nervous system tumours<\/span>\n        <span class=\"dlw-tumor-item\">Non-small cell lung cancer<\/span>\n        <span class=\"dlw-tumor-item\">Sarcoma<\/span>\n        <span class=\"dlw-tumor-item\">Other cancer types<\/span>\n    <\/div>\n\n    <div class=\"dlw-image-block\">\n        <img decoding=\"async\"\n            src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/08\/Imagen2-2.webp\"\n            alt=\"Recommended tumour types for the FUSIONPlex Pan Solid Tumor v2 panel\"\n            class=\"dlw-prod-img\"\n            onclick=\"openDlwModal(this.src)\"\n        >\n    <\/div>\n\n    <h2>PROTOCOL<\/h2>\n\n    <div class=\"dlw-card-grid\">\n        <div class=\"dlw-protocol-card\">\n            <h3>Standard version<\/h3>\n\n            <p>\n                The panel is designed for use with <strong>Illumina\u00ae<\/strong> and\n                <strong>Ion Torrent\u00ae<\/strong> sequencers. The workflow is efficient\n                and structured around two rounds of multiplex PCR, with library\n                preparation taking approximately 1.5 days.\n            <\/p>\n\n            <p>\n                It requires a minimum amount of RNA or total nucleic acid (TNA),\n                typically between <strong>10 and 250 ng<\/strong>, extracted from\n                FFPE samples or other clinical sources.\n            <\/p>\n        <\/div>\n\n        <div class=\"dlw-protocol-card\">\n            <h3>HT version (high throughput)<\/h3>\n\n            <p>\n                The panel is optimised for high-throughput workflows and\n                <strong>Illumina\u00ae<\/strong> sequencers. It enables the simultaneous\n                preparation of multiple libraries in 96-well plates using a\n                scalable and automatable protocol that retains the sensitivity\n                and accuracy of the standard design.\n            <\/p>\n\n            <p>\n                An input amount of <strong>10 to 200 ng of RNA or TNA<\/strong> per\n                sample is recommended, making it suitable for laboratories with a\n                high analytical workload.\n            <\/p>\n        <\/div>\n    <\/div>\n\n    <div class=\"dlw-image-block\">\n        <img decoding=\"async\"\n            src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/08\/Imagen3-1.webp\"\n            alt=\"FUSIONPlex Pan Solid Tumor v2 library preparation workflow\"\n            class=\"dlw-prod-img\"\n            onclick=\"openDlwModal(this.src)\"\n        >\n    <\/div>\n\n    <h2>SOFTWARE<\/h2>\n\n    <div class=\"dlw-list\">\n        <span class=\"dlw-list-item\">\n            Analysis performed using <strong>Archer&#x2122; Analysis<\/strong> software.\n        <\/span>\n\n        <span class=\"dlw-list-item\">\n            Identification of known and novel gene fusions without requiring prior\n            knowledge of the fusion partner.\n        <\/span>\n\n        <span class=\"dlw-list-item\">\n            Detection of relevant alternative transcripts and splice variants.\n        <\/span>\n\n        <span class=\"dlw-list-item\">\n            Use of molecular barcodes for read deduplication and accurate\n            quantification of the original molecules.\n        <\/span>\n\n        <span class=\"dlw-list-item\">\n            Correction of systematic sequencing and amplification errors.\n        <\/span>\n\n        <span class=\"dlw-list-item\">\n            Generation of clear and customisable reports to facilitate the\n            interpretation of results.\n        <\/span>\n    <\/div>\n\n    <h2>SPECIFICATIONS<\/h2>\n\n    <p>\n        The <strong>FUSIONPlex\u00ae Pan Solid Tumor v2<\/strong> panel provides broad\n        coverage of clinically relevant genes associated with a wide range of\n        solid tumours.\n    <\/p>\n\n    <div class=\"dlw-image-block\">\n        <img decoding=\"async\"\n            src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/08\/Imagen4-1.webp\"\n            alt=\"FUSIONPlex Pan Solid Tumor v2 panel specifications\"\n            class=\"dlw-prod-img\"\n            onclick=\"openDlwModal(this.src)\"\n        >\n    <\/div>\n\n    <div class=\"dlw-feature-grid\">\n        <span class=\"dlw-feature-card\">\n            RNA-based targeted NGS panel.\n        <\/span>\n\n        <span class=\"dlw-feature-card\">\n            Detection of known and novel gene fusions.\n        <\/span>\n\n        <span class=\"dlw-feature-card\">\n            Detection of relevant alternative transcripts and splice variants.\n        <\/span>\n\n        <span class=\"dlw-feature-card\">\n            Compatible with RNA or total nucleic acid extracted from FFPE samples\n            and other clinical sources.\n        <\/span>\n\n        <span class=\"dlw-feature-card\">\n            Standard workflow compatible with Illumina\u00ae and Ion Torrent\u00ae\n            sequencing platforms.\n        <\/span>\n\n        <span class=\"dlw-feature-card\">\n            High-throughput HT workflow optimised for Illumina\u00ae platforms.\n        <\/span>\n\n        <span class=\"dlw-feature-card\">\n            Library preparation in approximately 1.5 days.\n        <\/span>\n\n        <span class=\"dlw-feature-card\">\n            Molecular barcodes for deduplication and accurate molecule\n            quantification.\n        <\/span>\n    <\/div>\n\n    <h2>COMPLETE GENE LIST<\/h2>\n\n    <div class=\"dlw-gene-box\">\n        <p>\n            AKT1 \u00b7 ALK \u00b7 AR \u00b7 ARAF \u00b7 BRAF \u00b7 BRCA1 \u00b7 BRCA2 \u00b7 CCND1 \u00b7 CDK4 \u00b7\n            CDK6 \u00b7 CIC \u00b7 EGFR \u00b7 ERBB2 \u00b7 ERG \u00b7 ESR1 \u00b7 EWSR1 \u00b7 FGFR1 \u00b7 FGFR2 \u00b7\n            FGFR3 \u00b7 FOXO1 \u00b7 FUS \u00b7 JAK2 \u00b7 KIT \u00b7 KRAS \u00b7 MAML2 \u00b7 MDM2 \u00b7 MET \u00b7\n            MSH2 \u00b7 MYB \u00b7 MYBL1 \u00b7 NTRK1 \u00b7 NTRK2 \u00b7 NTRK3 \u00b7 NRAS \u00b7 NRG1 \u00b7\n            PDGFRA \u00b7 PDGFRB \u00b7 PIK3CA \u00b7 PPARG \u00b7 PRKCA \u00b7 PRKCB \u00b7 RAF1 \u00b7\n            RELA \u00b7 RET \u00b7 ROS1 \u00b7 RSPO2 \u00b7 RSPO3 \u00b7 TERT \u00b7 TFE3 \u00b7 TFEB \u00b7\n            TMPRSS2 \u00b7 VGLL2\n        <\/p>\n    <\/div>\n\n    <div class=\"dlw-image-block\">\n        <img decoding=\"async\"\n            src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/08\/Imagen5.webp\"\n            alt=\"Complete gene content of the FUSIONPlex Pan Solid Tumor v2 panel\"\n            class=\"dlw-prod-img\"\n            onclick=\"openDlwModal(this.src)\"\n        >\n    <\/div>\n\n<\/div>\n\n<div\n    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