{"id":8254,"date":"2019-12-02T12:43:02","date_gmt":"2019-12-02T12:43:02","guid":{"rendered":"https:\/\/www.dlongwood.com\/fusionplex-sarcoma-v2-3\/"},"modified":"2025-05-15T10:08:57","modified_gmt":"2025-05-15T10:08:57","slug":"fusionplex-sarcoma-v2","status":"publish","type":"productos","link":"https:\/\/www.dlongwood.com\/en\/product-catalog\/fusionplex-sarcoma-v2\/","title":{"rendered":"FusionPlex\u00ae Sarcoma v2"},"content":{"rendered":"\n<p>The FusionPlex\u00ae Sarcoma v2 panel is a targeted <strong>next-generation sequencing<\/strong> (NGS) research product that expands on FusionPlex\u00ae Sarcoma panel. The updated design covers <strong>key fusions and variants in 63 genes <\/strong>relevant in sarcomas.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-full\"><a href=\"https:\/\/dlongwood.com\/wp-content\/uploads\/2021\/10\/fusionplex-sarcoma-v2.png\" target=\"_blank\" rel=\"noopener noreferrer\"><img decoding=\"async\" src=\"https:\/\/dlongwood.com\/wp-content\/uploads\/2021\/10\/fusionplex-sarcoma-v2.png\" alt=\"\" class=\"wp-image-9757\" title=\"\"><\/a><\/figure><\/div>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>FusionPlex\u00ae uses <strong>RNA<\/strong> instead of DNA as input material, which allows for <strong>more accurate and more cost-effective fusion detection<\/strong> than DNA-based hybrid capture techniques. FusionPlex\u00ae places gene-specific primers near known fusion breakpoints to identify RNA abnormalities with a single primer. Because FusionPlex\u00ae can identify <strong>known and novel alterations<\/strong> with a limited number of primers, it can detect fusions more efficiently and accurately than DNA-based approaches.<\/p>\n\n\n\n<p><strong>Archer Analysis <\/strong>software allows the analysis and interpretation of the NGS data.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"has-text-color\" style=\"color:#003a70\"><strong>Comprehensive Fusion Detection<\/strong><\/p>\n\n\n\n<p>AMP\u2122 chemistry utilizes open-ended targeted amplification to identify gene fusions whether or not the fusion partner is known.<\/p>\n\n\n\n<p class=\"has-text-color\" style=\"color:#003a70\"><strong>Quiver\u00ae Fusion Database<\/strong><\/p>\n\n\n\n<p>Powerful fusion analysis combined with a curated database of relevant known translocations.<\/p>\n\n\n\n<p class=\"has-text-color\" style=\"color:#003a70\"><strong>Low Input<\/strong><\/p>\n\n\n\n<p>Purpose-built for wide sample type compatibility, including low-input and degraded samples such as FFPE tissue.<\/p>\n\n\n\n<p class=\"has-text-color\" style=\"color:#003a70\"><strong>Simple <strong>Workflow<\/strong>, Lyophilized Reagents<\/strong><\/p>\n\n\n\n<p>Easy-to-handle lyophilized reagents and a simple workflow to minimize errors and reduce turn-around time.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Gene Targets<\/strong><\/td><td>63<\/td><\/tr><tr><td><strong>Input Nucleic Acid Required*<\/strong><\/td><td>\u226510 ng<\/td><\/tr><tr><td><strong>Unique Molecular On-Target %<\/strong><\/td><td>>95%<\/td><\/tr><tr><td><strong>Sample Types<\/strong><\/td><td>Fresh, frozen and FFPE<\/td><\/tr><tr><td><strong>Hands-On Time<\/strong><\/td><td>3.5 hours<\/td><\/tr><tr><td><strong>Total Time<\/strong><\/td><td>1.5 days<\/td><\/tr><tr><td><strong>Platform<\/strong><\/td><td>Illumina\u00ae e Ion Torrent\u2122<\/td><\/tr><\/tbody><\/table><figcaption>*Input mass requirements vary depending on type and quality. Unless the tumor cellularity and sample quality are high, 50ng of FFPE-derived nucleic acid should be considered the minimum recommendation. If input is not limiting, 200ng is recommended.<\/figcaption><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>NGS assays associated with soft tissue cancers.<\/p>\n","protected":false},"featured_media":7611,"template":"","tecnologias":[36],"marcas":[217],"familias":[460,470,347,464],"class_list":["post-8254","productos","type-productos","status-publish","has-post-thumbnail","hentry","tecnologias-next-generation-sequencing-ngs","marcas-archer-dx-en","familias-fusions","familias-soft-tissues","familias-solid-tumor","familias-tumor-types"],"_links":{"self":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/8254","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos"}],"about":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/types\/productos"}],"version-history":[{"count":0,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/8254\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media\/7611"}],"wp:attachment":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media?parent=8254"}],"wp:term":[{"taxonomy":"tecnologias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/tecnologias?post=8254"},{"taxonomy":"marcas","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/marcas?post=8254"},{"taxonomy":"familias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/familias?post=8254"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}