{"id":8430,"date":"2019-12-03T13:56:17","date_gmt":"2019-12-03T13:56:17","guid":{"rendered":"https:\/\/www.dlongwood.com\/genvinset-hla-a29-2\/"},"modified":"2025-05-15T11:30:48","modified_gmt":"2025-05-15T11:30:48","slug":"genvinset-hla-a29","status":"publish","type":"productos","link":"https:\/\/www.dlongwood.com\/en\/product-catalog\/genvinset-hla-a29\/","title":{"rendered":"Genvinset\u00ae HLA A29"},"content":{"rendered":"\n<h4 class=\"wp-block-heading\">Information about the product<\/h4>\n\n\n\n<p class=\"justificar\">Birdshot retinochoroidopathy (BSRC) is a rare, chronic, bilateral, posterior uveitis characterized by distinctive, multiple, hypopigmented choroidal and retinal lesions. The pathogenesis is unknown, but HLA-A29 positivity appears to confer predisposition, and retinal autoimmunity seems to play a role.<\/p>\n\n\n\n<p class=\"justificar\">The relative risk of BSRC among HLA-A29-positive individuals has been estimated to be 50 to 224, and most investigators recognize the presence of the HLA-A29 allele as a necessary criterion for BSRC diagnosis for research purposes. HLA-A29 is present in as many as 7% of Caucasians, and is subdivi\u00acded into more than 20 subtypes.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Intended use<\/h4>\n\n\n\n<p class=\"justificar\">Genvinset\u00ae HLA A29 is a semi-automated\u00a0<em>in vitro<\/em>\u00a0diagnostic kit for the qualitative detection of the HLA-A*29 group of alleles in genomic DNA extracted from whole blood, associated with Birdshot retinochoroidopathy predisposition, by real-time PCR using TaqMan\u00ae probes technology.<\/p>\n\n\n\n<p class=\"justificar\">Patients who can benefit from this determination are those referred by a specialist. The results of this test should not be the only ones on which the therapeutic decision is based and should be used as an aid in the diagnosis together with results of other markers of the disease.<\/p>\n\n\n\n<p class=\"justificar\">The intended user of the kit is technical personnel trained to carry out the protocol and the interpretation of results described in the instructions for use.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Workflow<\/h4>\n\n\n\n<div style=\"height:22px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2023\/01\/workflow_genvinset-2.png\" alt=\"\" class=\"wp-image-14603\" width=\"250\" height=\"121\" title=\"\"><figcaption><\/figcaption><\/figure>\n\n\n\n<div style=\"height:31px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\">Results<\/h4>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-full\"><img decoding=\"async\" src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2023\/01\/Genvinset-HLA-A29-Negative-sample.jpg\" alt=\"\" class=\"wp-image-14741\" title=\"\"><\/figure><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-full\"><img decoding=\"async\" src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2023\/01\/Genvinset-HLA-A29-Positive-sample.jpg\" alt=\"\" class=\"wp-image-14743\" title=\"\"><\/figure><\/div>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-full\"><img decoding=\"async\" src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2023\/01\/leyenda-8.jpg\" alt=\"\" class=\"wp-image-14746\" title=\"\"><\/figure><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><\/div>\n<\/div>\n\n\n\n<h4 class=\"wp-block-heading\">Limitations<\/h4>\n\n\n\n<ul class=\"justificar wp-block-list\"><li>Mutations or polymorphisms at annealing primer\/probe sites are possible and may result in the lack of allele definition. Other technologies could be necessary to resolve the typing.<\/li><li>Data and result interpretation should be revised by qualified personnel.<\/li><li>This product is an auxiliary tool for the diagnosis of patients with suspected birdshot retinochoroidopathy. Use these results in conjunction with clinical data and results of other tests performed on the patient.<\/li><\/ul>\n","protected":false},"excerpt":{"rendered":"<p>GENVINSET HLA-A29 detects HLA-A29 group of allelesby real time PCR<\/p>\n","protected":false},"featured_media":8428,"template":"","tecnologias":[275],"marcas":[225],"familias":[283,323,367,284,441],"class_list":["post-8430","productos","type-productos","status-publish","has-post-thumbnail","hentry","tecnologias-rt-pcr-en","marcas-blackhills-diagnostic-resources-en","familias-molecular-genetics","familias-hla-associated-diseases-immunology","familias-hla-associated-diseases-molecular-genetics","familias-immunology","familias-targeted_study_of_specific_pathologies"],"_links":{"self":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/8430","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos"}],"about":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/types\/productos"}],"version-history":[{"count":0,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/8430\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media\/8428"}],"wp:attachment":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media?parent=8430"}],"wp:term":[{"taxonomy":"tecnologias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/tecnologias?post=8430"},{"taxonomy":"marcas","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/marcas?post=8430"},{"taxonomy":"familias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/familias?post=8430"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}