{"id":8454,"date":"2019-12-03T14:31:22","date_gmt":"2019-12-03T14:31:22","guid":{"rendered":"https:\/\/www.dlongwood.com\/genvinset-behcet-hla-b51-52-2\/"},"modified":"2025-05-15T11:31:03","modified_gmt":"2025-05-15T11:31:03","slug":"genvinset-behcet-hla-b51-52","status":"publish","type":"productos","link":"https:\/\/www.dlongwood.com\/en\/product-catalog\/genvinset-behcet-hla-b51-52\/","title":{"rendered":"Genvinset\u00ae HLA Beh\u00e7et v5"},"content":{"rendered":"\n<h4 class=\"wp-block-heading\">Information about the product<\/h4>\n\n\n\n<p class=\"justificar\">Beh\u00e7et\u2019s disease (BD) is a form of vasculitis that manifests with urogenital ulcers, uveitis, skin inflammation, arthritis, enterocolitis and inflammation in other organs. Despite being a worldwide-distributed illness, BD is more frequent in the area that extends from East Asia to the Mediterranean basin. It is also relatively common in countries such as Turkey and Japan.<\/p>\n\n\n\n<p class=\"justificar\">According to various scienti\ufb01c studies, there are several genetic factors that partially determine the susceptibility to develop the illness. More speci\ufb01cally, it is known that BD is associated with the HLA-B*5 antigen, belonging to the Major Histocompatibility Complex (MCH), encoded by the HLA-B*51\/52 group of alleles. Therefore, the HLA-B*5 antigen is a risk factor strongly associated with BD.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Intended use<\/h4>\n\n\n\n<p class=\"justificar\">Genvinset\u00ae HLA Beh\u00e7et v5 is a semi-automated\u00a0<em>in vitro<\/em>\u00a0diagnostic kit for the qualitative detection of the HLA-B*51\/52 group of alleles in genomic DNA extracted from whole blood, associated with Beh\u00e7et\u2019s disease predisposition, by Real-Time PCR using TaqMan\u00ae probes technology.<\/p>\n\n\n\n<p class=\"justificar\">Patients who can benefit from this determination are those referred by a specialist. The results of this test should not be the only ones on which the therapeutic decision is based and should be used as an aid in the diagnosis together with results of other markers of the disease.<\/p>\n\n\n\n<p class=\"justificar\">The intended user of the kit is technical personnel trained to carry out the protocol and the interpretation of results described in the Instructions for Use.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Workflow<\/h4>\n\n\n\n<div style=\"height:22px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2023\/01\/workflow_genvinset-2.png\" alt=\"\" class=\"wp-image-14603\" width=\"250\" height=\"121\" title=\"\"><figcaption><\/figcaption><\/figure>\n\n\n\n<div style=\"height:31px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h4 class=\"wp-block-heading\">Results<\/h4>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-large\"><img decoding=\"async\" src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2023\/01\/Graficas-web-Behcet-1024x342.png\" alt=\"\" class=\"wp-image-14755\" title=\"\"><\/figure><\/div>\n<\/div>\n<\/div>\n\n\n\n<h4 class=\"wp-block-heading\">Limitations<\/h4>\n\n\n\n<ul class=\"justificar wp-block-list\"><li>Mutations or polymorphisms at annealing primer\/probe sites are possible and may result in the lack of allele definition. Other technologies could be necessary to resolve the typing.<\/li><li>Data and result interpretation should be revised by qualified personnel.<\/li><li>This product is an auxiliary tool for the diagnosis of patients with suspected Beh\u00e7et\u2019s disease. Use these results in conjunction with clinical data and results of other tests performed on the patient.<\/li><\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Kit for detecting the HLA-B*51 and B*52 alleles by Real-Time PCR using TaqMan\u00ae probes technology<\/p>\n","protected":false},"featured_media":8452,"template":"","tecnologias":[275],"marcas":[225],"familias":[283,367,323,284,441],"class_list":["post-8454","productos","type-productos","status-publish","has-post-thumbnail","hentry","tecnologias-rt-pcr-en","marcas-blackhills-diagnostic-resources-en","familias-molecular-genetics","familias-hla-associated-diseases-molecular-genetics","familias-hla-associated-diseases-immunology","familias-immunology","familias-targeted_study_of_specific_pathologies"],"_links":{"self":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/8454","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos"}],"about":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/types\/productos"}],"version-history":[{"count":0,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/8454\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media\/8452"}],"wp:attachment":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media?parent=8454"}],"wp:term":[{"taxonomy":"tecnologias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/tecnologias?post=8454"},{"taxonomy":"marcas","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/marcas?post=8454"},{"taxonomy":"familias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/familias?post=8454"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}