{"id":8926,"date":"2019-12-02T13:52:02","date_gmt":"2019-12-02T13:52:02","guid":{"rendered":"https:\/\/www.dlongwood.com\/liquidplex-ctdna-28-3\/"},"modified":"2026-08-24T11:35:18","modified_gmt":"2026-08-24T11:35:18","slug":"liquidplex-ctdna-28","status":"publish","type":"productos","link":"https:\/\/www.dlongwood.com\/en\/product-catalog\/liquidplex-ctdna-28\/","title":{"rendered":"LIQUIDPlex Universal solid tumor"},"content":{"rendered":"\n<!-- Complete HTML ready for WordPress \/ Bricks -->\n<style>\n.dlw-prod-wrapper {\n  width: 100% !important;\n  max-width: 720px !important;\n  margin: 0 auto;\n  overflow: hidden;\n  color: #263746;\n  font-family: \"Raleway\", Arial, sans-serif;\n  line-height: 1.7;\n  box-sizing: border-box;\n}\n\n.dlw-prod-wrapper *,\n.dlw-prod-wrapper *::before,\n.dlw-prod-wrapper *::after {\n  box-sizing: border-box;\n}\n\n.dlw-prod-wrapper h1,\n.dlw-prod-wrapper h2,\n.dlw-prod-wrapper h3 {\n  margin-top: 0;\n  color: #003a70;\n  font-family: \"Playfair 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<section class=\"dlw-prod-hero\">\n    <h1>LIQUIDPlex&#x2122; Universal Solid Tumor<\/h1>\n    <p>Next-generation sequencing panel for the analysis of circulating cell-free DNA using Anchored Multiplex PCR technology.<\/p>\n  <\/section>\n\n  <section class=\"dlw-prod-section\">\n    <div class=\"dlw-prod-heading\">\n      <h2>Overview<\/h2>\n    <\/div>\n\n    <p>The LIQUIDPlex&#x2122; Universal Solid Tumor panel is designed for next-generation sequencing (NGS) from circulating cell-free DNA (cfDNA), using the proprietary Anchored Multiplex PCR (AMP&#x2122;) technology.<\/p>\n\n    <p>AMP&#x2122; technology (Anchored Multiplex PCR) is a proprietary targeted enrichment platform for next-generation sequencing (NGS). It is based on the use of unidirectional gene-specific primers (GSPs) and molecular adapters with unique molecular barcodes (MBCs), which are ligated to the genetic material before amplification. This strategy enables the efficient capture and amplification of DNA, RNA or cfDNA fragments, even in the presence of unknown mutations or highly fragmented sequences.<\/p>\n\n    <div class=\"dlw-prod-img-wrap\">\n      <img decoding=\"async\"\n        class=\"dlw-prod-img\"\n        src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/08\/Imagen1-4.webp\"\n        alt=\"Diagram of Anchored Multiplex PCR AMP technology\"\n        loading=\"lazy\"\n        onclick=\"dlwOpenImage(this)\"\n      >\n    <\/div>\n\n    <p>The anchored primer architecture supports a flexible design and reduces information loss during library preparation. Combined with Archer&#x2122; Analysis software, AMP&#x2122; enables systematic error correction, read deduplication and accurate quantification of original molecules, facilitating the detection of point variants, indels, gene fusions and copy number alterations with high sensitivity and specificity.<\/p>\n  <\/section>\n\n  <section class=\"dlw-prod-section dlw-prod-section-alt\">\n    <div class=\"dlw-prod-heading\">\n      <h2>Recommended tumor types<\/h2>\n    <\/div>\n\n    <p>Breast cancer, lung cancer (NSCLC), colorectal cancer, melanoma and other solid tumors.<\/p>\n\n    <div class=\"dlw-prod-img-wrap\">\n      <img decoding=\"async\"\n        class=\"dlw-prod-img\"\n        src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/08\/Imagen2-4.webp\"\n        alt=\"Solid tumor types recommended for the LIQUIDPlex panel\"\n        loading=\"lazy\"\n        onclick=\"dlwOpenImage(this)\"\n      >\n    <\/div>\n  <\/section>\n\n  <section class=\"dlw-prod-section\">\n    <div class=\"dlw-prod-heading\">\n      <h2>Protocol<\/h2>\n    <\/div>\n\n    <p>The panel is designed for use with Illumina\u00ae sequencing platforms. The workflow uses Anchored Multiplex PCR (AMP&#x2122;) technology and consists of multiple steps, including two PCR rounds with gene-specific primers and adapters containing molecular barcodes (MBCs). Library preparation is completed in approximately one and a half days.<\/p>\n\n    <p>The protocol is optimized for circulating cell-free DNA (cfDNA) and supports sample inputs ranging from 5 to 300 ng, obtained from plasma or other compatible sources.<\/p>\n\n    <div class=\"dlw-prod-img-wrap\">\n      <img decoding=\"async\"\n        class=\"dlw-prod-img\"\n        src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/08\/Imagen3-3.webp\"\n        alt=\"LIQUIDPlex Universal Solid Tumor protocol workflow\"\n        loading=\"lazy\"\n        onclick=\"dlwOpenImage(this)\"\n      >\n    <\/div>\n  <\/section>\n\n  <section class=\"dlw-prod-section dlw-prod-section-alt\">\n    <div class=\"dlw-prod-heading\">\n      <h2>Software<\/h2>\n    <\/div>\n\n    <div class=\"dlw-list\">\n      <span class=\"dlw-list-item\">Archer&#x2122; Analysis is a comprehensive bioinformatics platform developed by IDT for the automated analysis of NGS data generated with panels from the Archer\u00ae family, including FUSIONPlex&#x2122;, VARIANTPlex&#x2122; and LIQUIDPlex&#x2122;. It enables comprehensive molecular analyses from DNA or RNA, tailored to each sample type and clinical or research application.<\/span>\n\n      <span class=\"dlw-list-item\">It is compatible with sequencing data from Illumina\u00ae platforms\u2014FUSIONPlex&#x2122;, VARIANTPlex&#x2122; and LIQUIDPlex&#x2122;\u2014and Ion Torrent&#x2122; platforms\u2014FUSIONPlex&#x2122; only.<\/span>\n\n      <span class=\"dlw-list-item\">The platform runs pipelines optimized for each technology. For LIQUIDPlex&#x2122;, it supports highly sensitive circulating DNA (cfDNA) analysis, including SNVs, indels and molecular barcode-based (MBC) quantification for samples with a low variant allele fraction.<\/span>\n\n      <span class=\"dlw-list-item\">Archer&#x2122; Analysis provides an intuitive and secure web interface for viewing detected variants, applying customized filters, generating automated reports and performing clinical annotations with tools such as ClinVar, COSMIC and Ensembl, among other reference databases.<\/span>\n\n      <span class=\"dlw-list-item\">Designed for regulated environments, it provides complete traceability, reproducible analyses and scalability for laboratories working with advanced genomic profiling in cancer, from research to clinical applications under RUO or CE-IVD labeling, depending on the panel configuration.<\/span>\n    <\/div>\n  <\/section>\n\n  <section class=\"dlw-prod-section\">\n    <div class=\"dlw-prod-heading\">\n      <h2>Specifications<\/h2>\n    <\/div>\n\n    <div class=\"dlw-detection-box\">\n      <span class=\"dlw-detection-icon\">+<\/span>\n      <div>\n        <strong>Broad detection capability<\/strong>\n        SNVs, indels and CNVs.\n      <\/div>\n    <\/div>\n\n    <div class=\"dlw-prod-img-wrap\">\n      <img decoding=\"async\"\n        class=\"dlw-prod-img\"\n        src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/08\/Imagen4-3.webp\"\n        alt=\"LIQUIDPlex panel specifications and detection capabilities\"\n        loading=\"lazy\"\n        onclick=\"dlwOpenImage(this)\"\n      >\n    <\/div>\n\n    <div class=\"dlw-feature-grid\">\n      <article class=\"dlw-feature-card\">\n        <h3>AMP&#x2122; technology<\/h3>\n        <p>Improves sensitivity and accuracy in the detection of genetic alterations.<\/p>\n      <\/article>\n\n      <article class=\"dlw-feature-card\">\n        <h3>Optimized for cfDNA<\/h3>\n        <p>Suitable for low-quality samples.<\/p>\n      <\/article>\n\n      <article class=\"dlw-feature-card\">\n        <h3>Starting amount of genetic material<\/h3>\n        <p>Requires only 5 ng of cfDNA.<\/p>\n      <\/article>\n\n      <article class=\"dlw-feature-card\">\n        <h3>Universal compatibility<\/h3>\n        <p>Compatible with Illumina\u00ae sequencers.<\/p>\n      <\/article>\n\n      <article class=\"dlw-feature-card\">\n        <h3>Bioinformatics support<\/h3>\n        <p>Includes the Archer\u00ae Analysis platform for data analysis and visualization.<\/p>\n      <\/article>\n    <\/div>\n  <\/section>\n\n  <section class=\"dlw-prod-section dlw-prod-section-alt\">\n    <div class=\"dlw-prod-heading\">\n      <h2>Complete gene list<\/h2>\n    <\/div>\n\n    <div class=\"dlw-prod-img-wrap\">\n      <img decoding=\"async\"\n        class=\"dlw-prod-img\"\n        src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2026\/08\/Imagen5-2.webp\"\n        alt=\"Complete list of genes included in LIQUIDPlex Universal Solid Tumor\"\n        loading=\"lazy\"\n        onclick=\"dlwOpenImage(this)\"\n      >\n    <\/div>\n\n    <div class=\"dlw-prod-note\">Click the image to enlarge it and view the complete gene list.<\/div>\n  <\/section>\n<\/div>\n\n<div\n  id=\"dlw-image-modal\"\n  class=\"dlw-image-modal\"\n  role=\"dialog\"\n  aria-modal=\"true\"\n  aria-label=\"Enlarged image view\"\n  onclick=\"dlwBackdropClose(event)\"\n>\n  <button\n    type=\"button\"\n    class=\"dlw-modal-close\"\n    aria-label=\"Close image\"\n    onclick=\"dlwCloseImage()\"\n  >&times;<\/button>\n\n  <div class=\"dlw-modal-content\">\n    <img decoding=\"async\" id=\"dlw-modal-image\" class=\"dlw-modal-image\" src=\"\" alt=\"\" title=\"\">\n  <\/div>\n<\/div>\n\n<script>\nfunction dlwOpenImage(imageElement) {\n  var modal = document.getElementById(\"dlw-image-modal\");\n  var modalImage = document.getElementById(\"dlw-modal-image\");\n\n  modalImage.src = imageElement.src;\n  modalImage.alt = imageElement.alt || \"Enlarged image\";\n  modal.classList.add(\"dlw-modal-open\");\n  document.body.style.overflow = \"hidden\";\n}\n\nfunction dlwCloseImage() {\n  var modal = document.getElementById(\"dlw-image-modal\");\n  var modalImage = document.getElementById(\"dlw-modal-image\");\n\n  modal.classList.remove(\"dlw-modal-open\");\n  modalImage.src = \"\";\n  document.body.style.overflow = \"\";\n}\n\nfunction dlwBackdropClose(event) {\n  if (event.target.id === \"dlw-image-modal\") {\n    dlwCloseImage();\n  }\n}\n\ndocument.addEventListener(\"keydown\", function(event) {\n  if (event.key === \"Escape\") {\n    dlwCloseImage();\n  }\n});\n<\/script>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>NGS assay to study 28 genes commonly associated with solid tumor type cancers from circulating cell-free tumor DNA (ccfDNA\/cfDNA\/ctDNA).<\/p>\n","protected":false},"featured_media":7591,"template":"","tecnologias":[36],"marcas":[217],"familias":[347,465,466,459,468,469,464],"class_list":["post-8926","productos","type-productos","status-publish","has-post-thumbnail","hentry","tecnologias-next-generation-sequencing-ngs","marcas-archer-dx-en","familias-solid-tumor","familias-digestive-system","familias-endocrine-system","familias-liquid-biopsy","familias-reproductive-system","familias-respiratory-system","familias-tumor-types"],"_links":{"self":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/8926","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos"}],"about":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/types\/productos"}],"version-history":[{"count":1,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/8926\/revisions"}],"predecessor-version":[{"id":28286,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/8926\/revisions\/28286"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media\/7591"}],"wp:attachment":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media?parent=8926"}],"wp:term":[{"taxonomy":"tecnologias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/tecnologias?post=8926"},{"taxonomy":"marcas","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/marcas?post=8926"},{"taxonomy":"familias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/familias?post=8926"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}