{"id":8926,"date":"2019-12-02T13:52:02","date_gmt":"2019-12-02T13:52:02","guid":{"rendered":"https:\/\/www.dlongwood.com\/liquidplex-ctdna-28-3\/"},"modified":"2025-05-15T10:09:50","modified_gmt":"2025-05-15T10:09:50","slug":"liquidplex-ctdna-28","status":"publish","type":"productos","link":"https:\/\/www.dlongwood.com\/en\/product-catalog\/liquidplex-ctdna-28\/","title":{"rendered":"LIQUIDPlex Universal solid tumor"},"content":{"rendered":"\n<p>The LIQUIDPlex<sup>TM<\/sup> ctDNA 28 Kit is an advanced and user-friendly solution for targeted next generation sequencing (NGS) of circulating cell-free tumor DNA (ccfDNA\/cfDNA\/ctDNA) from 28 genes commonly associated with solid tumor type cancers.<\/p>\n\n\n\n<p><strong>Relevant Fragment Capture<\/strong><\/p>\n\n\n\n<p><strong>Anchored Multiplex PCR<\/strong> (AMP\u2122)-based target enrichment preferentially enriches for highly fragmented ctDNA over high molecular weight genomic DNA to <strong>reduce background and increase detection sensitivity of low-allele fraction (AF) mutations.<\/strong><\/p>\n\n\n\n<p><strong>Single-day library prep<\/strong><\/p>\n\n\n\n<p>NGS-ready libraries can be prepared in under 8 hours with 2.5 hours of hands-on time, providing <strong>sequencing results in as little as 3 days.<\/strong><\/p>\n\n\n\n<p><strong>Error correction &#038; Quantitative Analysis<\/strong><\/p>\n\n\n\n<p>Molecular barcode sequences ligated prior to amplification enable duplicate read binning and advanced error correction for confident variant calls.<\/p>\n\n\n\n<p><strong>Sensitive &#038; Specific Variant Detection<\/strong><\/p>\n\n\n\n<p>Reliably detect high AF (5%) variants using as little as 5ng total cfDNA input and low AF (1%) variants from as little as 10ng.<\/p>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>Solution for Illumina platforms. Access to Archer Analysis software for data analysis and interpretation.<\/p>\n\n\n\n<p>Genes: <\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/dlongwood.com\/wp-content\/uploads\/2019\/11\/archer-reveal-ctDNA28-genes-1024x215.png\" alt=\"\" class=\"wp-image-2144\" title=\"\"><figcaption><\/figcaption><\/figure>\n\n\n\n<p>The LIQUIDPlex<sup>TM<\/sup> ctDNA 28 assay can be combined with the VariantPlex (DNA-based) and FusionPlex (RNA-based) products for a more comprehensive view of these genetic studies.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>NGS assay to study 28 genes commonly associated with solid tumor type cancers from circulating cell-free tumor DNA (ccfDNA\/cfDNA\/ctDNA).<\/p>\n","protected":false},"featured_media":7591,"template":"","tecnologias":[36],"marcas":[217],"familias":[465,466,459,468,469,347,464],"class_list":["post-8926","productos","type-productos","status-publish","has-post-thumbnail","hentry","tecnologias-next-generation-sequencing-ngs","marcas-archer-dx-en","familias-digestive-system","familias-endocrine-system","familias-liquid-biopsy","familias-reproductive-system","familias-respiratory-system","familias-solid-tumor","familias-tumor-types"],"_links":{"self":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/8926","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos"}],"about":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/types\/productos"}],"version-history":[{"count":0,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/8926\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media\/7591"}],"wp:attachment":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media?parent=8926"}],"wp:term":[{"taxonomy":"tecnologias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/tecnologias?post=8926"},{"taxonomy":"marcas","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/marcas?post=8926"},{"taxonomy":"familias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/familias?post=8926"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}