{"id":8965,"date":"2019-11-20T13:18:37","date_gmt":"2019-11-20T13:18:37","guid":{"rendered":"https:\/\/www.dlongwood.com\/mentype-amlplex-acute-myeloid-leukemia-2\/"},"modified":"2025-02-12T07:53:20","modified_gmt":"2025-02-12T07:53:20","slug":"mentype-amlplex-acute-myeloid-leukemia","status":"publish","type":"productos","link":"https:\/\/www.dlongwood.com\/en\/product-catalog\/mentype-amlplex-acute-myeloid-leukemia\/","title":{"rendered":"Mentype\u00ae AMLplex &#8211; acute myeloid leukemia"},"content":{"rendered":"\n<p>Mentype\u00ae AMLplex<sup>QS<\/sup> allows the identification of <strong>11 gene fusions and 34 transcript variants<\/strong> associated with acute myeloid leukaemia (AML).<\/p>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.dlongwood.com\/wp-content\/uploads\/2022\/09\/image-1.png\" alt=\"\" class=\"wp-image-13175\" width=\"548\" height=\"695\" title=\"\"><\/figure><\/div>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>The assay is based on a multiplex PCR reaction with subsequent fragment analysis by capillary electrophoresis. RNA isolated from blood or bone marrow must first be transcribed into cDNA. Primers are fluorescence-labeled with 6-FAM\u2122, BTG or BTY, allowing <strong>rapid and sensitive analysis<\/strong> by the aforementioned capillary electrophoresis.<\/p>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/dlongwood.com\/wp-content\/uploads\/2019\/11\/biotype-amlplex-grafico-1024x529.png\" alt=\"\" class=\"wp-image-1868\" title=\"\"><figcaption><\/figcaption><\/figure>\n\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>The amount of isolated RNA and the quality of the reverse transcription reaction will be shown by the included ABL control. Successful multiplex amplification is monitored by a control-amplification of the internal quality sensor \u201cQS\u201d. Furthermore,\u00a0a cDNA carrying the AML1-ETO translocation is enclosed as a positive control.<\/p>\n\n\n\n<p>Mentype\u00ae AMLplex<sup>QS<\/sup> represents your reliable diagnostics for <strong>precise, highly sensitive and routine-fit analysis<\/strong> of fusion gene transcripts in acute myeloid leukaemia.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<figure class=\"wp-block-gallery columns-4 is-cropped wp-block-gallery-1 is-layout-flex wp-block-gallery-is-layout-flex\"><ul class=\"blocks-gallery-grid\"><li class=\"blocks-gallery-item\"><figure><a href=\"https:\/\/dlongwood.com\/wp-content\/uploads\/2019\/11\/biotype_carrusel_4.jpg\" target=\"_blank\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/dlongwood.com\/wp-content\/uploads\/2019\/11\/biotype_carrusel_4.jpg\" alt=\"\" data-id=\"1300\" data-link=\"https:\/\/dlongwood.com\/?attachment_id=1300\" class=\"wp-image-1300\" title=\"\"><\/a><\/figure><\/li><li class=\"blocks-gallery-item\"><figure><a href=\"https:\/\/dlongwood.com\/wp-content\/uploads\/2019\/11\/biotype_carrusel_1.jpg\" target=\"_blank\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/dlongwood.com\/wp-content\/uploads\/2019\/11\/biotype_carrusel_1.jpg\" alt=\"\" data-id=\"1302\" data-link=\"https:\/\/dlongwood.com\/?attachment_id=1302\" class=\"wp-image-1302\" title=\"\"><\/a><\/figure><\/li><li class=\"blocks-gallery-item\"><figure><a href=\"https:\/\/dlongwood.com\/wp-content\/uploads\/2019\/11\/biotype_carrusel_2.jpg\" target=\"_blank\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/dlongwood.com\/wp-content\/uploads\/2019\/11\/biotype_carrusel_2.jpg\" alt=\"\" data-id=\"1304\" data-link=\"https:\/\/dlongwood.com\/?attachment_id=1304\" class=\"wp-image-1304\" title=\"\"><\/a><\/figure><\/li><li class=\"blocks-gallery-item\"><figure><a href=\"https:\/\/dlongwood.com\/wp-content\/uploads\/2019\/11\/biotype_carrusel_3.jpg\" target=\"_blank\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/dlongwood.com\/wp-content\/uploads\/2019\/11\/biotype_carrusel_3.jpg\" alt=\"\" data-id=\"1306\" data-link=\"https:\/\/dlongwood.com\/?attachment_id=1306\" class=\"wp-image-1306\" title=\"\"><\/a><\/figure><\/li><\/ul><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Detection of chromosomal aberrations in acute myeloid leukemia (AML).<\/p>\n","protected":false},"featured_media":8961,"template":"","tecnologias":[37],"marcas":[220],"familias":[336,340],"class_list":["post-8965","productos","type-productos","status-publish","has-post-thumbnail","hentry","tecnologias-fragment-analysis","marcas-biotype-en","familias-oncohematology","familias-myeloid-line"],"_links":{"self":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/8965","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos"}],"about":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/types\/productos"}],"version-history":[{"count":0,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/productos\/8965\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media\/8961"}],"wp:attachment":[{"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/media?parent=8965"}],"wp:term":[{"taxonomy":"tecnologias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/tecnologias?post=8965"},{"taxonomy":"marcas","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/marcas?post=8965"},{"taxonomy":"familias","embeddable":true,"href":"https:\/\/www.dlongwood.com\/en\/wp-json\/wp\/v2\/familias?post=8965"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}