Genvinset HLA-BEHÇET’S DISEASE (HLA-B*51/52)

Behçet’s disease (BD) is a form of vasculitis that manifests with orogenital ulcers, uveitis, skin inflammation, arthritis, enterocolitis and inflammation in other organs. BD is associated with the major histocompatibility complex HLA–B5 allele and, more specifically, with HLA–B51, the predominant split of the HLA–B5 broad antigen. HLA-B*51 is, therefore, the most strongly associated risk factor for Behçet’s disease, which has been confirmed in multiple populations.

The detection method used by Genvinset HLA BEHÇET’S DISEASE is based in a primer specific PCR, which anneal to specific HLA-B*51/52 group of alleles monitored with Taqman probes. At the same time the method amplifies and detects a control gene (β-globin) to verify the assay's result.