Prolaris®
Prognostic test to determine tumour aggressiveness and 10-year disease-specific mortality in patients with primary localised prostate cancer.
GeoMx Cancer Transcriptome Atlas (CTA)
CatalogOncologySolid Tumor
Spatial study of the expression of over 1,800 genes involved in tumour biology, tumour microenvironment and immune response.
The GeoMx ® Cancer Transcriptome Atlas (CTA) is designed for a comprehensive profiling of tumor biology, the tumor microenvironment, and the immune response, with spatial resolution from distinct regions of interest with a single tissue section.
This panel allows you to profile the expression of over 1,800 genes covering around 100 pathways. You will be able to:
- Profile the global immune response
- Assess microenvironment immune activity
- Quantify tumor reactivity to the immune response and therapeutic treatments
- Profile heterogeneous tumors, covering clinically derived gene sets (Tumor Inflammation Signature (TIS), PAM50…)
Furthermore, it can be customized with up to 60 additional targets of interest.
The GeoMx® CTA is compatible with RNAscope® technology and antibody morphology markers for tissue imaging and ROIs selection.
The read out is performed by Next-Generation Sequencing (NGS), and the software GeoMx DSP data center provides an end-to-end software solution from image acquisition and region of interest selection to a fully integrated data analysis experience.
For more information about the pathways and processes included in the panel, please, consult the product file you can download below or visit the NanoString web:
Presentations
| Product | Product Description | Quantity | Catalog Number |
|---|---|---|---|
| GeoMx Cancer Transcriptome Atlas Human RNA for Illumina Systems | RNA panel including over 1,800 targets plus controls for human immune response, tumor biology, and microenvironment. Includes RNA probes for Illumina NGS read out | 4 slides | GMX-RNA-NGS-CTA-4 |
| GeoMx Solid Tumor TME Morphology Kit Human RNA Compatible | Morphology kit for visualization of human solid tumors and the tumor microenvironment. For use with RNA assays. Includes fluorescent antibodies against Pan-CK, CD45, and a nuclear stain | 12 slides | GMX-RNA-MORPH-HST-12 |
| GeoMx Melanoma TME Morphology Kit Human RNA Compatible | Morphology kit for visualization of human melanoma and the tumor microenvironment. For use with RNA assays. Includes fluorescent antibodies against S100B/Pmel17, CD45, and a nuclear stain | 12 slides | GMX-RNA-MORPH-HMEL-12 |
| GeoMx Seq Code Pack Compatible with Illumina Systems | NGS readout reagents for GeoMx DSP RNA and protein analysis. Includes two Seq Code primer plates (choice of A&B, C&D, E&F, o G&H) and two universal enzyme master mixes | 192 areas of interest (AOI) | GMX-NGS-SEQ-[XX] |
| GeoMx RNA Slide Prep Kit for FFPE | Sample prep reagents for GeoMx DSP RNA analysis. Includes Buffer W, Buffer S, and Buffer R | 12 slides | GMX-PREP-RNA-FFPE-12 |
| GeoMx DSP Collection Plate | Barcoded collection plates for use in the GeoMx DSP. Required for AOI tracking. Kit includes 12 plates covering 1,152 AOI | 1 pack | GMX-DSP-COLL-PLT |
| GeoMx DSP Instrument Buffer Kit | Buffer kit for the GeoMx DSP. Includes Buffer S and Buffer H. Sufficient for -48 samples with -18 AOI each. Volume requirements may vary based on experimental design | 1 kit | GMX-DSP-BUFF-KIT |
