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GeoMx Cancer Transcriptome Atlas (CTA)

CatalogOncologySolid Tumor

Spatial study of the expression of over 1,800 genes involved in tumour biology, tumour microenvironment and immune response.

The GeoMx ® Cancer Transcriptome Atlas (CTA) is designed for a comprehensive profiling of tumor biology, the tumor microenvironment, and the immune response, with spatial resolution from distinct regions of interest with a single tissue section.

This panel allows you to profile the expression of over 1,800 genes covering around 100 pathways. You will be able to:

  • Profile the global immune response
  • Assess microenvironment immune activity
  • Quantify tumor reactivity to the immune response and therapeutic treatments
  • Profile heterogeneous tumors, covering clinically derived gene sets (Tumor Inflammation Signature (TIS), PAM50…)

Furthermore, it can be customized with up to 60 additional targets of interest.

The GeoMx® CTA is compatible with RNAscope® technology and antibody morphology markers for tissue imaging and ROIs selection.

The read out is performed by Next-Generation Sequencing (NGS), and the software GeoMx DSP data center provides an end-to-end software solution from image acquisition and region of interest selection to a fully integrated data analysis experience.

For more information about the pathways and processes included in the panel, please, consult the product file you can download below or visit the NanoString web:

Web de NanoString

Presentations

ProductProduct DescriptionQuantityCatalog Number
GeoMx Cancer Transcriptome Atlas Human RNA for Illumina SystemsRNA panel including over 1,800 targets plus controls for human immune response, tumor biology, and microenvironment. Includes RNA probes for Illumina NGS read out4 slidesGMX-RNA-NGS-CTA-4
GeoMx Solid Tumor TME Morphology Kit Human RNA CompatibleMorphology kit for visualization of human solid tumors and the tumor microenvironment. For use with RNA assays. Includes fluorescent antibodies against Pan-CK, CD45, and a nuclear stain12 slidesGMX-RNA-MORPH-HST-12
GeoMx Melanoma TME Morphology Kit Human RNA CompatibleMorphology kit for visualization of human melanoma and the tumor microenvironment. For use with RNA assays. Includes fluorescent antibodies against S100B/Pmel17, CD45, and a nuclear stain12 slidesGMX-RNA-MORPH-HMEL-12
GeoMx Seq Code Pack Compatible with Illumina SystemsNGS readout reagents for GeoMx DSP RNA and protein analysis. Includes two Seq Code primer plates (choice of A&B, C&D, E&F, o G&H) and two universal enzyme master mixes192 areas of interest (AOI)GMX-NGS-SEQ-[XX]
GeoMx RNA Slide Prep Kit for FFPESample prep reagents for GeoMx DSP RNA analysis. Includes Buffer W, Buffer S, and Buffer R 12 slidesGMX-PREP-RNA-FFPE-12
GeoMx DSP Collection PlateBarcoded collection plates for use in the GeoMx DSP. Required for AOI tracking. Kit includes 12 plates covering 1,152 AOI1 packGMX-DSP-COLL-PLT
GeoMx DSP Instrument Buffer KitBuffer kit for the GeoMx DSP. Includes Buffer S and Buffer H. Sufficient for -48 samples with -18 AOI each. Volume requirements may vary based on experimental design1 kitGMX-DSP-BUFF-KIT

Public Documentation

  • Product_Bulletin_MK2229_GeoMx_CTA_R6
  • TN_MK2495_ACD_Probes_R8
  • WhitePaper_MK2833_Introduction_to_GeoMx_Normalization_CTA_R5-1
  • BR_MK0981_GeoMx_Brochure_r19_FINAL_Single_WEB

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    Product families

    • Molecular Genetics
      • Prenatal Diagnosis
      • Triplet Expansion
      • Pharmacogenomics
      • Cystic Fibrosis
      • Other – Genetics
      • Genetic Panels
      • Reproduction
    • Hematology and blood bank
      • Platelet Antibody Testing
      • Cryopreservation
      • Blood Group Genotyping (RBC)
      • Other – Hematology
      • Thrombophilias and Hemochromatosis
    • Immunology and transplantation
      • Alloantibodies Detection
      • HLA-associated diseases
      • Immunosequencing
      • Other – Immunology
      • Chimerism
      • Immune response and biomarkers
      • HLA Typing
    • Microbiology
      • Virus
      • Fungus
      • DNA/RNA extraction
      • CMI Quick-Sepsis
      • Metatranscriptomics
    • Oncology
      • Oncohematology
      • Solid Tumor
    • Preanalytics
      • Sampling and Extraction
      • Blood collection
      • Sample transportation

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