DUPLICA REAL TIME Thrombophilias

DUPLICA REAL TIME FACTOR II G20210A. Coagulation disorders

Recently a new polymorphism are identified in the 3’- untranslated region of the prothrombin gene or Factor II, the G20210 transition (FII G20210A) which was found to be associated with an increased prothrombin levels in plasma and an increased risk of venous thrombosis.

DUPLICαRealTime FACTOR II Genotyping Kit was designed to identify a G20210A point mutation in factors II gene that is one of the most common inherited risk factor for Deep Vein Thrombosis.

Samples: EDTA collected peripheral whole blood

DUPLICA REAL TIME FACTOR V G1691A. Coagulation disorders

Resistance to activated protein C (APC) is a genetic factor that increase thrombotic risk. A number of clinical studies show a prevalence of activated protein C resistance of 20-60% among patients with venous thromboembolism

At least 90% of the cases with resistance to activated protein C are explained by a point mutation in the gene for coagulation factor V (Leiden mutation) causing substitution of Arg to Gln at position 506

RealTime FACTOR V Genotyping Kit was designed to identify a G1691A point mutation in factors  V gene that is one of the most common inherited risk factor for Deep Vein Thrombosis.

Sample: EDTA collected peripheral whole blood

DUPLICA REAL TIME MTHFR C677T. Coagulation disorders

One of the most common genetic defects of homocystein metabolism is a mutation in the enzyme MTHFR.  The most common MTHFR mutation is C677T causing substitution of Ala to Val at position 222 (Ala222Val). This mutation is associated with reduced enzyme activity and elevated total homocystein levels in serum or plasma.

DUPLICαRealTime MTHFR C677T Genotyping Kit was designed to identify C667T point mutation in a gene coding MTHFR enzyme.

Area:

Hematology, Hemochromatosis, Thrombophilias

Brand:

Documents:

Consult our experts

Google reCaptcha: Invalid site key.

Related products

Genvinset® HFE S65C

Kit for detecting the S65C mutation of HFE gene by Real Time PCR using TaqMan® probes technology Information about the product Hereditary hemochromatosis (HH) is an autosomal recessive inherited disorder of iron metabolism. Due to excessive intestinal absorption, iron accumulates in the parenchymal cells of the liver, pancreas, heart and other organs resulting in damage to its…
Blackhills Diagnostic Resources
Real Time PCR (qPCR)

Genvinset® HFE H63D

Kit for detecting the H63D mutation of HFE gene by Real Time PCR using TaqMan® probes technology Information about the product Hereditary hemochromatosis (HH) is an autosomal recessive inherited disorder of iron metabolism. Due to excessive intestinal absorption, iron accumulates in the parenchymal cells of the liver, pancreas, heart and other organs resulting in damage to its…
Blackhills Diagnostic Resources
Real Time PCR (qPCR)

Genvinset® HFE C282Y

Kit para la detección de la mutación C282Y del gen HFE mediante PCR en tiempo real, utilizando la tecnología de sondas TaqMan® Información sobre el producto La hemocromatosis hereditaria (HH) es un trastorno hereditario autosómico recesivo del metabolismo del hierro. Debido a una absorción intestinal excesiva, el hierro se acumula en las células parenquimatosas del hígado, el…
Blackhills Diagnostic Resources
Real Time PCR (qPCR)

Genvinset® MTHFR C677T

Kit para la detección del polimorfismo C677T del gen MTHFR por PCR en tiempo real, utilizando la tecnología de sondas TaqMan® Información sobre el producto La metiltetrahidrofolato reductasa (MTHFR) es una enzima clave en el metabolismo del folato. Aunque esta enzima no participa en la cascada de coagulación como otras proteínas (Factor II o el Factor V),…
Blackhills Diagnostic Resources
Real Time PCR (qPCR)