Devyser HBOC NGS is a fast and robust NGS solution aimed at the detection of germline variants in 12 genes associated with an increased risk of hereditary breast and ovarian cancer: ATM, BARD1, BRIP1, CDH1, CHEK2, NBN, PALB2, PTEN, RAD51C, RAD51D, STK11, TP53. It offers comprehensive and uniform coverage of all coding exons and exon/intron junctions of both genes. In addition, it includes the detection of single nucleotide variants (SNVs), insertions/deletions (Indels), and copy number variations (CNVs).

Key Features

Comprehensive detection of genetic variants in 12 relevant genes in hereditary breast and ovarian cancer.
Fast workflow: optimized for rapid results with same-day library preparation and less than 45 minutes of hands-on time.
Identification of germline and somatic variants, including CNV detection and 12 internal identity markers.
Dedicated software: Provides automated, user-friendly analysis, with options for batch export and efficient variant analysis without the need for bioinformatics expertise.

Clinical Applications

The panel is intended to identify variants in 12 genes implicated in the risk of developing breast and/or ovarian cancer: ATM, BARD1, BRIP1, CDH1, CHEK2, NBN, PALB2, PTEN, RAD51C, RAD51D, STK11, and TP53.

Intended Audience / User

Ideal for laboratories focused on the targeted analysis of genes related to breast and/or ovarian cancer predisposition.

Benefits

Streamlined workflow: easy to implement and suitable for laboratories with varying sample volume needs. Ready-to-use reagents, ensuring a reproducible process, and 12 sample identity markers are included to help minimize the risk of mix-ups associated with the use of two amplification mixes per sample. Intuitive software: facilitates the interpretation of obtained data, reducing the need for bioinformatics intervention.

Ordering Information

CE-IVD Marked
8-A111-24 24 tests.
8-A111-48 48 tests.
RUO Marked
8-A111-24-RUO 24 tests.
8-A111-48-RUO 48 tests.
Additional Reagents
8-A204 Devyser Library Clean

Area:

Hereditary cancer, Molecular Genetics, Targeted study of specific pathologies

Brand:

Consult our experts

Google reCaptcha: Invalid site key.

Related products

Hedera Profiling RNA Test Panel

In‑house targeted enrichment NGS panel for RNA profiling from tissue samples (FFPE). It analyzes 43 genes using a splice‑aware probe design anchored to exon boundaries. Detects fusions in a partner-agnostic manner, complex splicing variants, and gene expression profiles in a single workflow. Detailed Description Principle of operation End‑to‑end solution based on hybrid capture enrichment chemistry…
HederaDx
Next Generation Sequencing (NGS)

Hedera Profiling ctDNA 3

In‑house targeted enrichment NGS panel exclusively for liquid biopsy (cfDNA). It analyzes 43 genes with ESCAT I and II clinical evidence. Includes library preparation through an optimized workflow (DNA‑only) for plasma samples. Detects SNVs, Indels, CNVs, fusions and 36 microsatellite instability (MSI) markers. Detailed Description Principle of operation End‑to‑end solution based on hybridisation and capture…
HederaDx
Next Generation Sequencing (NGS)

Hedera Profiling 1 FFPE Test Panel (HP1)

In‑house targeted enrichment NGS panel for pan‑cancer solid tumor profiling. It analyzes 115 genes (79 with complete CDS) with ESCAT I, II and III clinical evidence. Includes library preparation through a flexible workflow that allows processing FFPE and cfDNA samples together or separately. Detects SNVs, Indels, CNVs, fusions, structural variants and MSI. Detailed Description PRINCIPLE…
HederaDx
Next Generation Sequencing (NGS)

Sepsis Pathogenic Microorganism Detection Kit (Digital PCR)

In vitro diagnostic kit based on droplet digital PCR (dPCR) for the detection of pathogenic microorganisms associated with sepsis from DNA extracted from clinical samples. The kit allows identification and quantification of pathogens without requiring blood culture, covering 21 frequent agents in bloodstream infections. Detailed Description Principle of operation The Sepsis Pathogenic Microorganism Detection Kit…
RainSure
Digital PCR