SCOPE™ Kits
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CatalogHematology and blood bankBlood Group Genotyping (RBC)
Natural Killer cells (NK cells) are important effector cells of the innate immunity system. In early phases of immune responses these lymphocytes participate in killing virus-infected and malignant cells.
There are activating as well as inhibitory KIRs, the latter recognizing MHC Class I particularly HLA-C molecules. The target cells get lysed, if the sum of the inhibitory KIR signals is weaker than that of the activating. This situation can lead to a Graft versus Leukemia effect (GVL) in bone marrow or stem cell recipients with absent HLA class I determinants, reducing the risk of relapse KIR Ready Gene kit enables molecular biological KIR typing based on the SSP method.
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