The Myeloid Solution by SOPHiA GENETICS is designed for the identification of mutations in 30 genes associated with Myelodysplastic Syndromes, Myeloproliferative Neoplasms and Leukemia, by Next-Generation Sequencing (NGS).
This diagnostic solution facilitates the selection of a personalized treatment, based on the genetic profile of each patient.
Genes and their association with diseases:
In addition to an accurate analysis of the key markers CEBPA, FLT3 (ITDs duplications) and CALR (large deletions), the kit allows the detection of SNVs, Indels and CNVs.
MYSplus panel is also available, which includes, in addition to the standard panel, RNA analysis for over 100 gene fusions.
Both, MYS and MYSplus kits, are based on NGS capture technology. The results are interpreted on the SOPHiA DDM platform, designed for the analysis and protection of NGS clinical data in the routine diagnosis.
In addition to the Myeloid Solutions, other panels for clinical diagnosis in areas such as metabolism, oncology, genetics and cardiology are available.
