iFIND® is an automated system for the detection and analysis of nucleic acids, based on microfluidic technology in a closed cartridge with preloaded lyophilized reagents. It is designed to offer an automated workflow from sample introduction to result acquisition, simplifying molecular diagnostics compared to conventional methods.
Detailed Description
Operating Principle
iFIND® integrates into a single automated system a closed microfluidic cartridge with preloaded lyophilized reagents. The process combines 7 functions in 1: enrichment, nucleic acid extraction, nucleic acid purification, liquid handling, mixing, amplification, and analysis.
Clinical Applications
Applications in pathogen detection for infectious diseases, drug resistance genes, and fungal genes:
Identification of Tuberculosis and resistance to rifampicin, isoniazid, and fluoroquinolones.
Identification of nontuberculous mycobacteria (NTM).
Fungal infections such as Candida and invasive fungi.
HAI and other infectious diseases: ESKAPE panel, carbapenem resistance genes, and Staphylococcus aureus / MRSA.
Gastrointestinal infections, with panels for viruses, bacteria, foodborne pathogens, and Clostridioides difficile.
Respiratory, including SARS-CoV-2 and other respiratory viruses.
Tropical diseases: Dengue, Zika, Chikungunya, and Hantavirus.
Benefits
iFIND® simplifies the process and reduces the operational complexity of traditional molecular diagnostics, allowing automated results to be obtained from the simple introduction of the sample into the preloaded cartridge and starting the equipment. The independent modular design allows the simultaneous performance of different assays, reducing turnaround times.
Technology Used
Nucleic acid extraction and purification by automated ultrasonication, chemical treatment, and automated purification by microfiltration membrane adsorption. After the nested PCR reaction, the system detects 6-channel fluorescence and performs melting curve analysis.
Target Audience/User
Clinical laboratories or departments, emergency services, outpatient care, and hospitals
Key Aspects
Closed cartridge with preloaded lyophilized reagents.
Independent modular design with S2, S4, and S8 configurations.
Multiplex detection of more than 10 targets in a single assay.
Time-to-report reduction to 30-100 minutes and up to 64 samples in 8 hours.
Automatic report generation and LIS connectivity via HL7.
Presentation Details
Equipment and Reagents
Available models for the equipment:
iFIND® S2 – 2 samples
iFIND® S4 – 4 samples
iFIND® S8 – 8 samples
Cartridge and reagents: for each assay, the cartridge, transfer pipette, and pretreatment buffer (if applicable) are included, with the option to include positive controls, negative control, and diluent.
CE-IVD assays in 10 or 50 test formats for multiple human tests.
| Test item | Product Name | Detection Target | Certification | Pack size | Cat. No. |
|---|---|---|---|---|---|
| ▶ Human | |||||
| TB | Mycobacterium Tuberculosis and Rifampicin Resistance Assay |
Identification of Mycobacterium tuberculosis complex: IS6110+IS1081 Rifampicin resistance: rpoB Gene 81bp Resistance determining region |
CE-IVD | 10T/box | 10210001A |
| 50T/box | 10210001B | ||||
| Mycobacterium Tuberculosis Isoniazid and Fluoroquinolone Resistance Assay |
Isoniazid katG, inhA and Fluoroquinolone gyrA resistance gene | CE-IVD | 10T/box | 10210102A | |
| 50T/box | 10210102B | ||||
| Mycobacteriaceae Identification Assay | Mycobacteriaceae, Mycobacterium tuberculosis complex, Mycobacterium avium, Mycolicibacterium fortuitum, Mycobacteroides abscessus, Mycobacterium kansasii, Mycobacteroides chelonae, Mycobacterium intracellulare and Mycobacterium gordonae. |
CE-IVD | 10T/box | 10210103A | |
| 50T/box | 10210103B | ||||
| Fungal infection | Five Candida Assay | Candida albicans, Candida tropicalis, Candida glabrata, Candida parapsilosis, and Candida krusei |
CE-IVD | 10T/box | 10210004A |
| 50T/box | 10210004B | ||||
| Five Invasive Fungal Assay | Aspergillus species, Cryptococcus neoformans, Pneumocystis jirovecii, Mucorales, and Talaromyces marneffei |
CE-IVD | 10T/box | 10210111A | |
| 50T/box | 10210111B | ||||
| HAI&Other infectious disease |
ESKAPE Multipathogenic Assay | Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumannii and Enterococcus |
CE-IVD | 10T/box | 10210106A |
| 50T/box | 10210106B | ||||
| Six Carbapenem-resistant Gene Assay | Carbapenem antibiotic resistance genes (including KPC, NDM, VIM, IMP, OXA-48, and OXA-23 genes) |
CE-IVD | 10T/box | 10210108A | |
| 50T/box | 10210108B | ||||
| Staphylococcus Aureus and Methicillin-resistant Staphylococcus Aureus Assay |
Staphylococcus aureus and Methicillin-resistant Staphylococcus aureus | CE-IVD | 10T/box | 10200163A | |
| 50T/box | 10200163B | ||||
| Gastrointestinal Infections |
Five Infectious Diarrhea Virus Assay | Norovirus (Type GI and GII), Sapovirus (Type I, II and V), Rotavirus (Group A, B and C), Astrovirus, and Enteric adenovirus |
CE-IVD | 10T/box | 10200145A |
| 50T/box | 10200145B | ||||
| Diarrhea Related Pathogen Nucleic Acid Detection Assay |
Clostridioides difficile, Yersinia enterocolitica, Campylobacter coli, Campylobacter jejuni, and Vibrio parahaemolyticus |
CE-IVD | 10T/box | 10210113A | |
| 50T/box | 10210113B | ||||
| Five Infectious Diarrhea Bacteria Assay | Vibrio parahaemolyticus, Salmonella, Shigella, Campylobacter jejuni and Campylobacter coli |
CE-IVD | 10T/box | 10200159A | |
| 50T/box | 10200159B | ||||
| Five Foodborne Bacteria Assay | Salmonella, Shigella, Enterohemorrhagic E. coli O157, Staphylococcus aureus, and Listeria monocytogenes |
CE-IVD | 10T/box | 10200160A | |
| 50T/box | 10200160B | ||||
| Clostridioides Difficile Assay | C. difficile tcdB (toxin B gene), cdtA (binary toxin gene), and deletion at position 117 of the tcdC gene |
CE-IVD | 10T/box | 10210110A | |
| 50T/box | 10210110B | ||||
| Respiratory | SARS-CoV-2 Assay | SARS-CoV-2 | CE-IVD | 10T/box | 10210121A |
| 50T/box | 10210121B | ||||
| Five Respiratory Pathogens Assay | Influenza A virus, Influenza B virus, Respiratory syncytial virus, Adenovirus, and SARS-CoV-2 |
CE-IVD | 10T/box | 10210120A | |
| 50T/box | 10210120B | ||||
| Tropical disease | Dengue virus & Zika virus & Chikungunya virus & Hantavirus Assay |
Dengue virus, Zika virus, Chikungunya virus, and Hantavirus | CE-IVD | 10T/box | 10200162A |
| 50T/box | 10200162B | ||||
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