Complete single-cell sequencing solutions, from sample to analysis of the resulting data.
Singleron’s SCOPE™ kits are designed to provide a comprehensive solution for single-cell sequencing, from sample to sequencing-ready library. They use Singleron’s proprietary patented microfluidic technology to enable the large-scale capture, separation and analysis of single cells while minimizing cellular stress.
Available kits
| Product | Applications |
|---|---|
| GEXSCOPE® Single Cell RNA Library Kit | Whole transcriptome |
| GEXSCOPE® Microbial Single Cell RNA Library Kit HD (Yeast) | Whole transcriptome (Designed for yeast analysis) |
| GEXSCOPE® Single Nucleus RNA Library Kit | Whole transcriptome Nuclei extraction required for frozen or paraffin-embedded (FFPE) tissues, or special samples (brain, muscle, adipose tissue…) |
| FocuSCOPE® Single Cell Targeted Sequencing Library Kit | Transcriptome + specific sequences (mutations, gene fusions, viral sequences) |
| sCircle® Single Cell Full-Length Immuno-receptor Library Kit | Transcriptome + full determination (Circularization) of V(D)J sequences TCR and BCR separately (Somatic hypermutation) |
| MobiuSCOPE Single Cell Full Length RNA Library Kit | Whole transcriptome with short-read sequencing (3’+5’) for alternative splicing, mutation/SNP detection, gene fusion identification, allele-specific gene expression patterns… |
| DynaSCOPE® Single Cell Dynamics RNA Library Kit | Transcriptome + Nascent RNA synthesis (in vivo/in vitro) |
| RetroSCOPE® FFPE Single Nucleus Transcriptome Library Kit | mRNA and non-coding RNA at single-cell level in FFPE tissues |
| scATAc-seq | Sequencing of open chromatin regions to uncover links to gene expression |
| ProMoSCOPE® Single Cell Glycosylation Detection Kit | Transcriptome + Cell-surface glycosylation |
| Clindex® Sample Multiplexing Kit | Multiplexing kit based on “click” chemistry. For pooling up to 16 samples in the same single-cell sequencing library |
| AccuraSCOPE® Single Cell Transcriptome and Genome Library Kit | Single-cell genome and transcriptome analysis (96-well plate) |
| AcuraCode® HTP One Step RNAseq Kit 96/384 well | Plate-based bulk RNA-Seq (96/384-well plate) |
Key features
SCOPE™ microchips: these Singleron chips can capture between 500 and 30,000 individual cells per sample, enabling detailed analysis of cellular heterogeneity and its microenvironment.
Broad applicability: compatible with a variety of applications, including the study of V(D)J sequences, detection of cell-surface glycosylation patterns, receptor analysis, single-cell transcriptome analysis and more.
High reproducibility: the different stages can be automated through to the final result, enabling multiple chips to be processed simultaneously and minimizing inter-assay variability
Analysis tools: not included by default, but they can be arranged as an additional service (specialized software) or used directly by the researcher, depending on the study requirements.
Easy to use: the manual protocol can be performed using a conventional P200 micropipette, without the need for specialized instruments.
