Complete single-cell sequencing solutions, from sample preparation to data analysis.
Singleron’s SCOPE™ kits are designed to provide a comprehensive solution for single-cell sequencing, from sample preparation to a sequencing-ready library. They utilize proprietary microfluidic technology to enable the capture, separation, and analysis of single cells on a large scale while minimizing cellular stress.
Available kits:
| Product | Applications |
|---|---|
| GEXSCOPE® Single Cell RNA Library Kit | Full transcriptome study |
| GEXSCOPE® Microbial Single Cell RNA Library Kit HD (Yeast) | Full transcriptome study (Designed for yeast analysis) |
| GEXSCOPE® Single Nucleus RNA Library Kit | Full transcriptome study. Necessary extraction of nuclei, frozen tissues or special samples (brain, muscle, fat, etc.) |
| FocuSCOPE® Single Cell Targeted Sequencing Library Kit | Full transcriptome + specific sequences (mutations, gene fusions, viral sequences) |
| GEXSCOPE® Single Cell Human V(D)J Kit Cell V2 | Full transcriptome + partial determination (3’) of V(D)J sequences (CD3 only). Simultaneous TCR and BCR |
| sCircle® Single Cell Full-Length Immuno-receptor Library Kit | Full transcriptome + complete determination (Circularisation) of V(D)J sequences. TCR and BCR separately (Somatic Hypermutation) |
| MobiuSCOPE Single Cell Full Length RNA Library Kit | Full transcriptome with short read sequencing (3’+5’) for alternative splicing, mutation detection/SNPs, identification of fusion genes, allele-specific gene expression patterns… |
| DynaSCOPE® Single Cell Dynamics RNA Library Kit | Full transcriptome + nascent RNA synthesis (in vivo / in vitro) |
| scATAC-seq | Uncovers gene expression links by sequencing open chromatin areas |
| ProMoSCOPE® Single Cell Glycosylation Detection Kit | Full transcriptome + Cell surface glycosylation |
| Clindex® Sample Multiplexing Kit | Click chemistry based multiplexing kit. For pooling up to 16 samples in the same single-cell sequencing library |
| AccuraSCOPE® Single Cell Transcriptome and Genome Library Kit | Single cell genome and transcriptome analysis (96-well plate) |
| AcuraCode® HTP One Step RNAseq Kit 96/384 well | Bulk RNA-Seq plate (96/384-well plate) |
Key features:
- SCOPE™ Microchips: These Singleron chips can capture between 500 and 30,000 individual cells per sample, allowing detailed analysis of cellular heterogeneity and their microenvironment.
- Broad applicability: Compatible with a variety of applications, including V(D)J sequencing studies, detection of cell surface glycosylation patterns, receptor studies, single-cell transcriptome analysis, and more.
- High reproducibility: Automation of various stages is possible until the result is obtained, allowing simultaneous processing of multiple chips and minimizing variability between assays.
- Analysis tools: not included by default, but can be managed as an additional service (specialised software) or carried out directly by the researcher, depending on the needs of the study.
- Easy to use: The manual protocol can be carried out using a conventional P200 micropipette, without the need for specialized instruments.
