Devyser BRCA PALB2 NGS is a fast and robust NGS solution designed for the detection of genetic variants in the BRCA1, BRCA2, and PALB2 genes. It offers comprehensive and uniform coverage of all coding exons and exon/intron junctions of both genes. In addition, it includes the detection of single nucleotide variants (SNVs), insertions/deletions (Indels), and copy number variations (CNVs), in both germline and somatic contexts.

Key Features

Comprehensive variant detection: Identifies relevant genetic variants in the BRCA1, BRCA2, and PALB2 genes, including CNVs.
Fast workflow: optimized for rapid results with same-day library preparation and less than 45 minutes of hands-on time.
A single workflow is easily and effectively applied to two applications: germline and somatic analysis.
Dedicated software: Provides automated, user-friendly analysis, with options for batch export and efficient variant analysis without the need for bioinformatics expertise.
Devyser BRCA PALB2 NGS Workflow

Intended Audience / User

Ideal for laboratories that need to comprehensively analyze the BRCA1, BRCA2, and PALB2 genes in a streamlined workflow. The targeted sequencing approach and uniform coverage of target regions maximize the retrieval of relevant data in every sequencing run.

Benefits

Streamlined workflow: easy to implement and suitable for laboratories with varying sample volume needs. Ready-to-use reagents, ensuring a reproducible process and reducing the risk of sample mix-ups or contamination. Compatible with germline and somatic analysis under the same workflow. Intuitive software: facilitates the interpretation of obtained data, reducing the need for bioinformatics intervention.

Additional Considerations

Starting material: Human genomic DNA extracted from whole blood or FFPE tissue. In FFPE samples, it is necessary to previously evaluate concentration and integrity, as initial sample quality can compromise the assay results.

Ordering Information

Devyser BRCA PALB2 Kits
8-A408-8 8 tests
8-A408-24 24 tests
8-A408-96 96 tests
Purification, Sequencing, and Analysis
Purification Devyser Library Clean (8-A204) for library purification.
Sequencing Sequencing on Illumina MiSeq.
Analysis Analysis in Amplicon Suite with Devyser BRCA PALB2 pipeline.

Area:

Hereditary cancer, Molecular Genetics, Solid tumor, Targeted study of specific pathologies

Brand:

Consult our experts

Google reCaptcha: Invalid site key.

Related products

Sepsis Pathogenic Microorganism Detection Kit (Digital PCR)

In vitro diagnostic kit based on droplet digital PCR (dPCR) for the detection of pathogenic microorganisms associated with sepsis from DNA extracted from clinical samples. The kit allows identification and quantification of pathogens without requiring blood culture, covering 21 frequent agents in bloodstream infections. Detailed Description Principle of operation The Sepsis Pathogenic Microorganism Detection Kit…
RainSure
Digital PCR

VIASURE 16S V1-V4 NGS Solution

NGS solution for library preparation aimed at the simultaneous identification and profiling of microbial species present in DNA extracted from original samples, through the analysis of the variable regions V1-V4 of the 16S rRNA gene. Product for research use only (RUO) and not intended for diagnostic procedures. Detailed Description Principle of operation VIASURE 16S V1-V4…
Certest
Next Generation Sequencing (NGS)

PN-900 CandidaGenius® C. auris screening assay

Real‑time PCR assay for the rapid and direct detection of Candida auris from non‑invasive swabs, without the need for prior culture. Detailed Description The PN-900 CandidaGenius® C. auris screening assay is a molecular tool designed for the qualitative detection of Candida auris DNA by real‑time PCR. This emerging fungus represents a growing challenge in the…
Pathonostics
Real Time PCR (qPCR)

Illumina Viral Surveillance Panel v2

Next‑generation sequencing (NGS) assay with hybrid capture enrichment for the detection and whole‑genome sequencing of approximately 200 RNA and DNA viruses relevant to public health. It integrates library preparation, enrichment, sequencing, and data analysis into an optimized workflow of about two days. Detailed Description Principle of operation The panel can start from RNA, DNA, or…
Illumina
Next Generation Sequencing (NGS)