DermaGenius® 2.0 Complete (PN-401), DermaGenius® 3.0 Nail (PN-302), DermaGenius® 3.0 Complete (PN-402), DermaGenius® Resistance (PN-303)

Multiplex real‑time PCR kits for the detection and differentiation of the most prevalent dermatophyte species in nail, skin, and hair samples.

Detailed Description

DermaGenius® kits are designed for the rapid and accurate detection of dermatophytic infections, providing high‑quality molecular diagnosis. These kits include versions for both dermatophyte species identification (DermaGenius® 2.0 and 3.0) and for the identification of resistance markers in Trichophyton (DermaGenius® Resistance). They are validated for use on nail, skin, and hair samples. • DermaGenius® 2.0/3.0 Complete: allow detection and differentiation of the most common dermatophyte species, such as Trichophyton rubrum, T. mentagrophytes, Microsporum canis, among others. The 3.0 kits include new targets (such as T. benhamiae and E. floccosum) and greater identification accuracy, especially with the use of the new kit versions. • DermaGenius® Resistance (PN-303): identifies the most important resistance markers in the SQLE gene, detecting specific mutations in genes that confer resistance to azole treatments, which is crucial for personalizing antifungal therapy. The DNA extraction process is carried out using the PathoNostics Extraction Kit (PN-502), which facilitates rapid sample preparation, followed by real‑time PCR amplification to provide results within two hours. These assays are ideal for laboratories seeking to improve accuracy and speed in the diagnosis of dermatophytic infections. The kits are validated on various real‑time PCR thermal cyclers, ensuring their versatility in different laboratory settings.

Key Features

Detection and differentiation of the main dermatophyte species: T. rubrum, T. mentagrophytes, M. canis, among others
Identification of resistance markers in the SQLE gene
Results in less than 2 hours
Compatible with nail, skin, and hair samples
Validated on several real‑time PCR systems
Use of PathoNostics Extraction Kit (PN-502) for DNA extraction

Presentation Details

DermaGenius® 2.0 Complete (PN-401)
Content: 50 reactions Targets: C. albicans, C. parapsilosis, S. brevicaulis, T. interdigitale, T. mentagrophytes, T. schoenleinii, T. tonsurans, T. rubrum, T. violaceum, and internal control Compatible instruments: LightCycler® 480 II, Rotor-Gene Q, QuantStudio™ 5, CFX96, Mic qPCR CE-IVDD
DermaGenius® 3.0 Complete (PN-402)
Content: 50 reactions Targets: T. benhamiae, T. verrucosum, M. canis, M. audouinii, E. floccosum, N. gypsae, and internal control Compatible instruments: LightCycler® 480 II, Rotor-Gene Q, QuantStudio™ 5, CFX96, Mic qPCR CE-IVDD
DermaGenius® Resistance (PN-303)
Content: 25 reactions Targets: SQLE resistance markers (mutations 393 and 397), T. interdigitale, T. mentagrophytes, T. rubrum, T. violaceum, and internal control Compatible instruments: LightCycler® 480 II, Rotor-Gene Q, QuantStudio™ 5, CFX96, Mic qPCR CE-IVDD
DermaGenius® 3.0 Nail (PN-302)
Content: 50 reactions Targets: Trichophyton rubrum, Trichophyton interdigitale, Candida albicans, Candida parapsilosis, Scopulariopsis brevicaulis, Internal Control Compatible instruments: LightCycler® 480 II, Rotor-Gene Q, QuantStudio™ 5, CFX96, Mic qPCR RUO
Extraction Kit (PN-502)
Content: 50 reactions Use for DNA extraction in dermatophyte samples
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