Antiretroviral therapy is subject to continuous changes and improvements whereby people currently treated for HIV live longer and have a better quality of life.
HIV virus is able to replicate very quickly in the individual, introducing during the replication process, several mutations which increase the ability to replicate even during antiretroviral drug treatments, treatments against which the virus can acquire resistance.
In the clinical setting, the availabity of a standardized test for genotyping and evaluating HIV drug resistance, is fundamental for the success of pharmacological treatments.
Target regions
Arrow Diagnostics HIV-1 solution kit is an in vitro method based on the amplification by RT-PCR of the viral RNA regions considered having a key role for the development of drug resistance (RT, Protease, Integrase and V3 Loop), followed by NGS sequencing and automatic result interpretation.
