Immunology

Optimized solution for high-resolution single-sample HLA typing using nanopore sequencing, ideal for environments requiring immediacy and flexibility. Detailed Description Nanotype® Mono is a compact solution from Werfen for high-resolution HLA typing based on nanopore sequencing technology (Oxford Nanopore Technologies), specially designed for the analysis of a single sample per run. It is ideal for laboratories…

Fast and accurate solution for high-resolution HLA typing using Oxford Nanopore sequencing technology, from sample to result in under 5 hours. Detailed Description Nanotype® is a comprehensive solution from Werfen for high-resolution HLA typing based on nanopore sequencing technology (Oxford Nanopore Technologies). Designed to deliver fast, accurate, and complete results, it provides detailed genomic information…

Digital PCR assay for the precise quantification of donor-derived cell-free DNA (dd-cfDNA) in transplant patients. Detailed Description HoloGRAFT ONE is a digital PCR (dPCR) assay developed by Werfen for the detection and quantification of donor-derived cell-free DNA (dd-cfDNA) in the plasma of transplant recipient patients. This molecular marker has established itself as a useful tool…

High-resolution NGS-based HLA typing system that supports multiple sequencing platforms and offers maximum workflow flexibility. Detailed Description HLA-SuBiTo NGStype® is a comprehensive solution for high-resolution HLA typing based on next-generation sequencing (NGS), developed by inno-train Diagnostik. The system allows the simultaneous analysis of up to 11 HLA loci using a long-range PCR approach, compatible with…

Comprehensive solution for chimerism study by qPCR, combining pre-transplant genetic typing kits and post-transplant quantitative monitoring. Detailed Description KMRtype® and KMRtrack® are complementary systems developed by GenDx for the characterization and monitoring of chimerism in transplant patients, using qPCR-based assays. The system allows everything from the identification of unique informative markers between recipient and donor,…

Ultra-fast solution for high-resolution HLA typing, featuring single-tube library preparation and sequencing using Oxford Nanopore technology. Detailed Description NGS-Turbo® is an innovative platform developed by GenDx for high-resolution HLA typing, specially designed for environments where speed and workflow simplicity are critical. This system combines full genomic amplification of 11 HLA loci with a single-tube library…

Matrices de separación para secuenciación.

Kit for detecting the HLA-C*06 alleles by Real Time PCR using TaqMan® probes technology Information about the product Psoriasis vulgaris is a chronic inflammatory disease of skin, which affects 2% of world population. The cutaneous manifestations of psoriasis are obvious and have a negative impact on quality of life of patients. Family studies have demonstrated…

Kit para la detección de los alelos HLA-DQB1*02, DQB1*03:02, DQA1*05 y DQA1*03 mediante PCR en tiempo real, Kit for detecting the HLA-DQB1*02, DQB1*03:02, DQA1*05 and DQA1*03 alleles by Real Time PCR using TaqMan® probes technology Information about the product Susceptibility to gluten sensitivity is, in part, genetically determined. The strong predisposition is associated with HLA-DQ…

Kit para la detección del alelo HLA-DQA1*05 mediante PCR en tiempo real utilizando la tecnología de sondas TaqMan®. Información del producto Varios estudios sugieren un papel del factor de necrosis tumoral alfa (TNF) en enfermedades crónicas inmunomediadas, como la enfermedad de Crohn, la enfermedad inflamatoria intestinal (EII), la psoriasis y la artritis reumatoide. Por ello,…

Neonatal screening tests for severe combined immunodeficiency, X-linked agammaglobulinaemia or Bruton's disease and spinal muscular atrophy.

Chimerism monitoring by NGS

Comprehensive expression study of genes from pathways, processes and cell types involved in neuroinflammation.

Study of gene expression aimed at the development of Stem Cell therapies.

Comprehensive gene expression study of myeloid-derived cells.

Gene expression study of genes related to T cell, B cell, and NK cell exhaustion in diverse contexts, including cancer and infectious disease.

Expression study of genes related to immunology.

Comprehensive study of genes involved in processes and mechanisms related to cancer progression, including essential genes for tumor biology, the tumoral microenvironment and the immune response.

Comprehensive study of dysfunctional cell signaling in cancer, including essential genes for the tumor biology, the tumoral microenvironment and the immune response.

Study of the early inflammatory response.

Comprehensive study of genes involved in major cancer pathways, including essential genes for the tumor biology, the tumoral microenvironment and the immune response.

Comprehensive study of genes involved in the tumoral immune evasion and the response to immunotherapy, including essential genes for the tumoral microenvironment and the immune response.

Study of the individual’s immune response to transplanted tissue.

Study of relevant genes in autoimmune disease, chronic inflammatory disease and immunotherapy-related adverse events (human panel and mouse panel).

Global study of the individual’s immune response (human or mouse) to infection.

High quality results with the eleven-loci multiplex

NGS kit for chimerism assessment

Kit for NGS sequencing of 17 genes that may impact the outcomes in transplantation

Kit for the relative quantitation, using plasma, of the donor derived cell free DNA, a great biomarker in the transplant follow-up.

Qualitative in vitro for diagnosis HLA class I and class II alleles typing kit with low resolution.